9HFS
 
 | | Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer with dCTP bound in the active site | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Cytidine and dCMP deaminase domain-containing protein 1, ZINC ION | | Authors: | Slyvka, A, Rathore, I, Yang, R, Kanai, T, Lountos, G, Wang, Z, Skowronek, K, Czarnocki-Cieciura, M, Wlodawer, A, Bochtler, M. | | Deposit date: | 2024-11-18 | | Release date: | 2025-04-30 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Activity and structure of human (d)CTP deaminase CDADC1.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9HFQ
 | | Cryo-EM structure of human CDADC1 inactive mutant (E400A): trimer without a ligand | | Descriptor: | Cytidine and dCMP deaminase domain-containing protein 1, ZINC ION | | Authors: | Slyvka, A, Rathore, I, Yang, R, Kanai, T, Lountos, G, Wang, Z, Skowronek, K, Czarnocki-Cieciura, M, Wlodawer, A, Bochtler, M. | | Deposit date: | 2024-11-18 | | Release date: | 2025-04-30 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Activity and structure of human (d)CTP deaminase CDADC1.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9HFT
 | | Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer with 5mdCTP bound in the active site | | Descriptor: | Cytidine and dCMP deaminase domain-containing protein 1, ZINC ION, [[(2~{R},3~{S},5~{R})-5-(4-azanyl-5-methyl-2-oxidanylidene-pyrimidin-1-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | | Authors: | Slyvka, A, Rathore, I, Yang, R, Kanai, T, Lountos, G, Wang, Z, Skowronek, K, Czarnocki-Cieciura, M, Wlodawer, A, Bochtler, M. | | Deposit date: | 2024-11-18 | | Release date: | 2025-04-30 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Activity and structure of human (d)CTP deaminase CDADC1.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9HFR
 | | Cryo-EM structure of human CDADC1 inactive mutant (E400A): hexamer without a ligand | | Descriptor: | Cytidine and dCMP deaminase domain-containing protein 1, ZINC ION | | Authors: | Slyvka, A, Rathore, I, Yang, R, Kanai, T, Lountos, G, Wang, Z, Skowronek, K, Czarnocki-Cieciura, M, Wlodawer, A, Bochtler, M. | | Deposit date: | 2024-11-18 | | Release date: | 2025-04-30 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Activity and structure of human (d)CTP deaminase CDADC1.
Proc.Natl.Acad.Sci.USA, 122, 2025
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6T22
 | | N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5hmCGA target sequence | | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*(5HC)P*GP*AP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*(5HC)P*GP*AP*TP*TP*C)-3'), EcoKMcrA modification dependent restriction endonuclease | | Authors: | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | | Deposit date: | 2019-10-07 | | Release date: | 2019-10-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
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6T21
 | | N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5mCGA target sequence | | Descriptor: | 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*TP*(5CM)P*GP*AP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*(5CM)P*GP*AP*TP*TP*C)-3') | | Authors: | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | | Deposit date: | 2019-10-07 | | Release date: | 2019-10-23 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
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6R64
 | | N-terminal domain of modification dependent EcoKMcrA restriction endonuclease (NEco) in complex with C5mCGG target sequence | | Descriptor: | 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*(5CM)P*GP*GP*TP*TP*C)-3') | | Authors: | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | | Deposit date: | 2019-03-26 | | Release date: | 2019-10-23 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
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8BV8
 | | Crystal structure of the phage Mu protein Mom inactive mutant S124A | | Descriptor: | Methylcarbamoylase mom | | Authors: | Silva, R.M.B, Slyvka, A, Lee, Y.J, Guan, C, Lund, S.R, Raleigh, E.A, Skowronek, K, Bochtler, M, Weigele, P.R. | | Deposit date: | 2022-12-08 | | Release date: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal structure of the phage Mu protein Mom catalytic mutant S124A
To Be Published
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6GHC
 | | Modification dependent EcoKMcrA restriction endonuclease | | Descriptor: | 5-methylcytosine-specific restriction enzyme A, ZINC ION | | Authors: | Czapinska, H, Kowalska, M, Zagorskaite, E, Manakova, E, Xu, S, Siksnys, V, Sasnauskas, G, Bochtler, M. | | Deposit date: | 2018-05-07 | | Release date: | 2018-08-08 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Activity and structure of EcoKMcrA.
Nucleic Acids Res., 46, 2018
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