2WLS
 
 | | Crystal structure of Mus musculus Acetylcholinesterase in complex with AMTS13 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Pang, Y.P, Ekstrom, F, Polsinelli, G.A, Gao, Y, Rana, S, Hua, D.H, Andersson, B, Andersson, P.O, Peng, L, Singh, S.K, Mishra, R.K, Zhu, K.Y, Fallon, A.M, Ragsdale, D.W, Brimijoin, S. | | Deposit date: | 2009-06-25 | | Release date: | 2009-09-08 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases.
Plos One, 4, 2009
|
|
7RRO
 | | Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia | | Descriptor: | Armadillo repeat containing 4, Chromosome 3 C1orf194 homolog, Cilia and flagella associated protein 161, ... | | Authors: | Gui, M, Anderson, J.R, Botsch, J.J, Meleppattu, S, Singh, S.K, Zhang, Q, Brown, A. | | Deposit date: | 2021-08-10 | | Release date: | 2021-10-27 | | Last modified: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | De novo identification of mammalian ciliary motility proteins using cryo-EM.
Cell, 184, 2021
|
|
1MBU
 | | Crystal Structure Analysis of ClpSN heterodimer | | Descriptor: | ATP-Dependent clp Protease ATP-Binding Subunit clp A, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, CHLORIDE ION, ... | | Authors: | Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D. | | Deposit date: | 2002-08-03 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA
J.Biol.Chem., 277, 2002
|
|
1MBV
 | | CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM | | Descriptor: | ATP-Dependent clp Protease ATP-Binding Subunit clp A, Protein yljA | | Authors: | Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D. | | Deposit date: | 2002-08-03 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of AAA+ Chaperone ClpA
J.Biol.Chem., 277, 2002
|
|
1MBX
 | | CRYSTAL STRUCTURE ANALYSIS OF ClpSN WITH TRANSITION METAL ION BOUND | | Descriptor: | ATP-Dependent clp Protease ATP-Binding Subunit clp A, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, CHLORIDE ION, ... | | Authors: | Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D. | | Deposit date: | 2002-08-03 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA
J.Biol.Chem., 277, 2002
|
|
2A65
 | | Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters | | Descriptor: | CHLORIDE ION, LEUCINE, Na(+):neurotransmitter symporter (Snf family), ... | | Authors: | Yamashita, A, Singh, S.K, Kawate, T, Jin, Y, Gouaux, E. | | Deposit date: | 2005-07-01 | | Release date: | 2005-08-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of a bacterial homologue of Na(+)/Cl(-)-dependent neurotransmitter transporters.
Nature, 437, 2005
|
|
2A5S
 | | Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate | | Descriptor: | GLUTAMIC ACID, N-methyl-D-aspartate receptor NMDAR2A subunit | | Authors: | Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E. | | Deposit date: | 2005-06-30 | | Release date: | 2005-11-15 | | Last modified: | 2017-07-26 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
|
|
2A5T
 | | Crystal Structure Of The NR1/NR2A ligand-binding cores complex | | Descriptor: | GLUTAMIC ACID, GLYCINE, N-methyl-D-aspartate receptor NMDAR1-4a subunit, ... | | Authors: | Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E. | | Deposit date: | 2005-06-30 | | Release date: | 2005-11-15 | | Last modified: | 2017-07-26 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
|
|
1R6C
 | | High resolution structure of ClpN | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpA | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-15 | | Release date: | 2005-02-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the
ClpA chaperone
J.Struct.Biol., 146, 2004
|
|
1R6B
 | | High resolution crystal structure of ClpA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ClpA protein, MAGNESIUM ION | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-15 | | Release date: | 2004-08-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
J.Struct.Biol., 146, 2004
|
|
1R6Q
 | | ClpNS with fragments | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein clpS, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, ... | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-16 | | Release date: | 2005-02-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
J.Struct.Biol., 146, 2004
|
|
1R6O
 | | ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein clpS, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, ... | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-15 | | Release date: | 2005-02-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the
ClpA chaperone
J.Struct.Biol., 146, 2004
|
|
3H5W
 | | Crystal structure of the GluR2-ATD in space group P212121 without solvent | | Descriptor: | Glutamate receptor 2 | | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | Deposit date: | 2009-04-22 | | Release date: | 2009-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.686 Å) | | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
|
|
3H5V
 | | Crystal structure of the GluR2-ATD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | Deposit date: | 2009-04-22 | | Release date: | 2009-06-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
|
|
3PAV
 | |
6XRE
 | | Structure of the p53/RNA polymerase II assembly | | Descriptor: | Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | | Authors: | Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W. | | Deposit date: | 2020-07-12 | | Release date: | 2021-03-24 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structure of the p53/RNA polymerase II assembly.
Commun Biol, 4, 2021
|
|
1HG9
 | | Solution structure of DNA:RNA hybrid | | Descriptor: | 5- D(*CP*TP*GP*AP*TP*AP*TP*GP*C) -3, 5- R(*GP*CP*AP*UP*AP*UP*CP*AP*G) -3 | | Authors: | Petersen, M, Bondensgaard, K, Wengel, J, Jacobsen, J.P. | | Deposit date: | 2000-12-13 | | Release date: | 2002-01-02 | | Last modified: | 2019-10-09 | | Method: | SOLUTION NMR | | Cite: | Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity.
Chemistry, 6, 2000
|
|
7PG9
 | | human 20S proteasome | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Xu, C, Cong, Y. | | Deposit date: | 2021-08-13 | | Release date: | 2021-10-20 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.
Nat Commun, 12, 2021
|
|
7V5M
 | | 20S+monoUb-CyclinB1-NT (S2) | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Xu, C, Cong, Y. | | Deposit date: | 2021-08-17 | | Release date: | 2021-09-22 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.88 Å) | | Cite: | The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.
Nat Commun, 12, 2021
|
|
7V5G
 | | 20S+monoUb-CyclinB1-NT (S1) | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Xu, C, Cong, Y. | | Deposit date: | 2021-08-17 | | Release date: | 2021-09-22 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (4.47 Å) | | Cite: | The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.
Nat Commun, 12, 2021
|
|
6O3Z
 | | Crystal structure of RORgt with 3-cyano-N-(3-{[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]methyl}-5-fluoro-2-methylphenyl)benzamide (compound 1) | | Descriptor: | 1,2-ETHANEDIOL, 3-cyano-N-(3-{[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]methyl}-5-fluoro-2-methylphenyl)benzamide, RAR-related orphan receptor C isoform a variant | | Authors: | Min, X, Wang, Z. | | Deposit date: | 2019-02-27 | | Release date: | 2020-03-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable ROR gamma t Inverse Agonists.
Acs Med.Chem.Lett., 11, 2020
|
|
5EYB
 | | X-ray Structure of Reb1-Ter Complex | | Descriptor: | DNA (26-MER), DNA-binding protein reb1 | | Authors: | Jaiswal, R, Choudhury, M, Zaman, S, Singh, S, Santosh, V, Bastia, D, Escalante, C.R. | | Deposit date: | 2015-11-24 | | Release date: | 2016-04-13 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Functional architecture of the Reb1-Ter complex of Schizosaccharomyces pombe.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5IVT
 | | Crystal Structure of HIV Protease complexed with [(1S)-1-[(S)-(4-chlorophenyl)-(3,5-difluorophenyl)methyl]-2-[[5-fluoro-4-[2-[(2R,5S)-5-(2,2,2-trifluoroethylcarbamoyloxymethyl)morpholin-4-ium-2-yl]ethyl]pyridin-1-ium-3-yl]amino]-2-oxo-ethyl]ammonium | | Descriptor: | (betaS)-4-chloro-beta-(3,5-difluorophenyl)-N-(5-fluoro-4-{2-[(2R,5S)-5-({[(2,2,2-trifluoroethyl)carbamoyl]oxy}methyl)morpholin-2-yl]ethyl}pyridin-3-yl)-L-phenylalaninamide, ACETATE ION, CHLORIDE ION, ... | | Authors: | Su, H.P. | | Deposit date: | 2016-03-21 | | Release date: | 2016-05-18 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Acs Med.Chem.Lett., 7, 2016
|
|
5IVR
 | |
5IVQ
 | |
