7V5M

20S+monoUb-CyclinB1-NT (S2)

Summary for 7V5M

• Entry DOI: 10.2210/pdb7v5m/pdb
• EMDB information: 31727
• Descriptor: Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (14 entities in total)
• Functional Keywords: 20s proteasome, human, substrate, ubiquitin, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 28
• Total formula weight: 717751.33

Authors

Xu, C.,Cong, Y. (deposition date: 2021-08-17, release date: 2021-09-22, Last modification date: 2022-03-30)

• Primary citation: Sahu, I.,Mali, S.M.,Sulkshane, P.,Xu, C.,Rozenberg, A.,Morag, R.,Sahoo, M.P.,Singh, S.K.,Ding, Z.,Wang, Y.,Day, S.,Cong, Y.,Kleifeld, O.,Brik, A.,Glickman, M.H.; The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.; Nat Commun, 12:6173-6173, 2021; PubMed: 34702852; DOI: 10.1038/s41467-021-26427-0

Experimental method

ELECTRON MICROSCOPY (3.88 Å)