5DJ3
 
 | | Structure of the PLP-Dependent L-Arginine Hydroxylase MppP with D-Arginine Bound | | 分子名称: | (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-D-arginine, MAGNESIUM ION, PLP-Dependent L-Arginine Hydroxylase MppP | | 著者 | Silvaggi, N.R, Han, L. | | 登録日 | 2015-09-01 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.227 Å) | | 主引用文献 | Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent l-Arginine alpha-Deaminase, gamma-Hydroxylase in the Enduracididine Biosynthetic Pathway.
Biochemistry, 54, 2015
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4JMD
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4JMC
 | | Enduracididine biosynthesis enzyme MppR complexed with pyruvate | | 分子名称: | PYRUVIC ACID, Putative uncharacterized protein mppR | | 著者 | Silvaggi, N.R. | | 登録日 | 2013-03-13 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Structural and Functional Characterization of MppR, an Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus: Functional Diversity in the Acetoacetate Decarboxylase-like Superfamily.
Biochemistry, 52, 2013
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4JM3
 | | Enduracididine Biosynthesis Enzyme MppR with HEPES Buffer Bound | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Putative uncharacterized protein mppR | | 著者 | Silvaggi, N.R. | | 登録日 | 2013-03-13 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Functional Characterization of MppR, an Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus: Functional Diversity in the Acetoacetate Decarboxylase-like Superfamily.
Biochemistry, 52, 2013
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4JME
 | | Enduracididine biosynthesis enzyme MppR complexed with 2-keto-enduracididine | | 分子名称: | (4R)-4-(2-carboxyethyl)imidazolidin-2-iminium, Putative uncharacterized protein mppR | | 著者 | Silvaggi, N.R. | | 登録日 | 2013-03-13 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Functional Characterization of MppR, an Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus: Functional Diversity in the Acetoacetate Decarboxylase-like Superfamily.
Biochemistry, 52, 2013
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4LZL
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4ZCD
 | | Renalase in complex with NAD+ | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Silvaggi, N.R, Moran, G.R, Roman, J.V. | | 登録日 | 2015-04-15 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6605 Å) | | 主引用文献 | Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-beta-NAD(P) Oxidase Activity from Pseudomonas phaseolicola.
Biochemistry, 54, 2015
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4ZCC
 | | Renalase in complex with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, ... | | 著者 | Silvaggi, N.R, Moran, G.R, Roman, J.V. | | 登録日 | 2015-04-15 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-beta-NAD(P) Oxidase Activity from Pseudomonas phaseolicola.
Biochemistry, 54, 2015
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6PAY
 | | Structure of HsICDH1:Mg(II):ICT:NADPH(50%) complex reveals structural basis for observation of half-sites reactivity | | 分子名称: | FORMIC ACID, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | | 著者 | Silvaggi, N.R, Melkonian, T.R, Roman, J.V, Moran, G.R. | | 登録日 | 2019-06-12 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States.
Biochemistry, 58, 2019
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5U8K
 | | RitR mutant - C128S | | 分子名称: | Response regulator | | 著者 | Silvaggi, N.R, Han, L. | | 登録日 | 2016-12-14 | | 公開日 | 2017-12-20 | | 最終更新日 | 2018-11-28 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
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7JME
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6C8T
 | | The structure of MppP soaked with the substrate L-Arg | | 分子名称: | (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-arginine, CHLORIDE ION, PLP-Dependent L-Arginine Hydroxylase MppP | | 著者 | Han, L, Silvaggi, N.R. | | 登録日 | 2018-01-25 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Streptomyces wadayamensis MppP is a PLP-Dependent Oxidase, Not an Oxygenase.
Biochemistry, 57, 2018
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1YQS
 | | Inhibition of the R61 DD-Peptidase by N-benzoyl-beta-sultam | | 分子名称: | 2-(BENZOYLAMINO)ETHANESULFONIC ACID, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | | 著者 | Ahmed, N, Cordaro, M, Laws, A.P, Delmarcelle, M, Silvaggi, N.R, Kelly, J.A, Page, M.I. | | 登録日 | 2005-02-02 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Inactivation of Bacterial dd-Peptidase by beta-Sultams.
Biochemistry, 44, 2005
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1IKI
 | | COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH THE PRODUCTS OF A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT | | 分子名称: | D-ALANINE, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANINE | | 著者 | Mcdonough, M.A, Anderson, J.W, Silvaggi, N.R, Pratt, R.F, Knox, J.R, Kelly, J.A. | | 登録日 | 2001-05-03 | | 公開日 | 2002-09-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.
J.Mol.Biol., 322, 2002
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1IKG
 | | MICHAELIS COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT | | 分子名称: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANYL-D-ALANINE | | 著者 | Mcdonough, M.A, Anderson, J.W, Silvaggi, N.R, Pratt, R.F, Knox, J.R, Kelly, J.A. | | 登録日 | 2001-05-03 | | 公開日 | 2002-09-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.
J.Mol.Biol., 322, 2002
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3U3H
 | | X-Ray Crystallographic Analysis of D-Xylose Isomerase-Catalyzed Isomerization of (R)-Glyceraldehyde | | 分子名称: | (2R)-propane-1,1,2,3-tetrol, (4R)-2-METHYLPENTANE-2,4-DIOL, FORMIC ACID, ... | | 著者 | Allen, K.N, Silvaggi, N.R, Toteva, M.M, Richard, J.P. | | 登録日 | 2011-10-05 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | Binding Energy and Catalysis by d-Xylose Isomerase: Kinetic, Product, and X-ray Crystallographic Analysis of Enzyme-Catalyzed Isomerization of (R)-Glyceraldehyde.
Biochemistry, 50, 2011
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1HVB
 | | CRYSTAL STRUCTURE OF STREPTOMYCES R61 DD-PEPTIDASE COMPLEXED WITH A NOVEL CEPHALOSPORIN ANALOG OF CELL WALL PEPTIDOGLYCAN | | 分子名称: | 5-{3-(S)-(4-(R)-ACETYLAMINO-4-CARBOXY-BUTYRYLAMINO)-3-[1-(R)-(1-(R)-CARBOXY-ETHYLCARBAMOYL)-ETHYLCARBAMOYL]-PROPYL}-2-( CARBOXY-PHENYLACETYLAMINO-METHYL)-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE | | 著者 | McDonough, M.A, Lee, W, Silvaggi, N.R, Mobashery, S, Kelly, J.A. | | 登録日 | 2001-01-08 | | 公開日 | 2001-02-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis.
Proc.Natl.Acad.Sci.USA, 98, 2001
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6C92
 | | The structure of MppP soaked with the product 2-ketoarginine | | 分子名称: | (4S)-5-carbamimidamido-4-hydroxy-2-oxopentanoic acid, (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-arginine, PLP-Dependent L-Arginine Hydroxylase MppP | | 著者 | Han, L, Silvaggi, N.R. | | 登録日 | 2018-01-25 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.834 Å) | | 主引用文献 | Streptomyces wadayamensis MppP is a PLP-Dependent Oxidase, Not an Oxygenase.
Biochemistry, 57, 2018
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6C9B
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7JQH
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7JQI
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7JQJ
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5BK7
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5BKA
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6EEJ
 | | Streptomyces bingchenggensis Aldolase-Dehydratase in covalent complex with dienone product. | | 分子名称: | (3E,5E)-6-(4-nitrophenyl)-2-oxohexa-3,5-dienoic acid, Acetoacetate decarboxylase, FORMIC ACID, ... | | 著者 | Mydy, L.S, Silvaggi, N.R. | | 登録日 | 2018-08-14 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | | 主引用文献 | Mechanistic Studies of theStreptomyces bingchenggensisAldolase-Dehydratase: Implications for Substrate and Reaction Specificity in the Acetoacetate Decarboxylase-like Superfamily.
Biochemistry, 58, 2019
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