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Structure of the PksA Product Template domain in complex with a phosphopantetheine mimetic
分子名称:	(14R)-14-hydroxy-15,15-dimethyl-1-[5-({[(5-methyl-1,2-oxazol-3-yl)methyl]sulfanyl}methyl)-1,2-oxazol-3-yl]-4,9,13-trioxo-2-thia-5,8,12-triazahexadecan-16-yl dihydrogen phosphate, Noranthrone synthase
著者	Tsai, S.C, Burkart, M.D, Townsend, C.A, Barajas, J.F, Shakya, G, Topper, C.L, Moreno, G, Jackson, D.R, Rivera, H, La Clair, J.J, Vagstad, A.
登録日	2016-06-03
公開日	2017-05-10
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.803 Å)
主引用文献	Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

Actinorhodin Polyketide Ketoreductase Mutant P94L bound to NADPH
分子名称:	FORMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ketoacyl reductase
著者	Korman, T.P, Javidpour, P, Tsai, S.-C.
登録日	2011-02-18
公開日	2011-05-25
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.792 Å)
主引用文献	Structural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide Ketoreductase. Biochemistry, 50, 2011

Actinorhodin Polyketide Ketoreductase Mutant P94L bound to NADPH and the Inhibitor Emodin
分子名称:	3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ketoacyl reductase
著者	Javidpour, P, Tsai, S.-C.
登録日	2011-04-12
公開日	2011-06-29
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.292 Å)
主引用文献	Structural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide Ketoreductase. Biochemistry, 50, 2011