3GBR
 
 | | Anthranilate phosphoribosyl-transferase (TRPD) double mutant D83G F149S from S. solfataricus | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Bruning, M, Schlee, S, Deuss, M, Ivens, A, Mayans, O, Sterner, R. | | Deposit date: | 2009-02-20 | | Release date: | 2009-12-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release
Biochemistry, 48, 2009
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2AKP
 | | Hsp90 Delta24-N210 mutant | | Descriptor: | ATP-dependent molecular chaperone HSP82 | | Authors: | Richter, K, Moser, S, Hagn, F, Friedrich, R, Hainzl, O, Heller, M, Schlee, S, Kessler, H, Reinstein, J, Buchner, J. | | Deposit date: | 2005-08-03 | | Release date: | 2006-01-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Intrinsic inhibition of the Hsp90 ATPase activity.
J.Biol.Chem., 281, 2006
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5EY5
 | | LBCATS | | Descriptor: | LBCA-b, LBCATS-a, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Busch, F, Rajendran, C, Schlee, S, Heyn, K, Merkl, R, Sterner, R. | | Deposit date: | 2015-11-24 | | Release date: | 2016-04-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.972 Å) | | Cite: | LBCATS
To Be Published
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4J35
 | | Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template | | Descriptor: | COBALT (II) ION, Phosphotriesterase, putative | | Authors: | Sterner, R, Raushel, F, Meier, M, Rajendran, C, Malisi, C, Fox, N, Schlee, S, Barondeau, D, Cker, B.H. | | Deposit date: | 2013-02-05 | | Release date: | 2013-07-24 | | Last modified: | 2013-09-04 | | Method: | X-RAY DIFFRACTION (1.783 Å) | | Cite: | Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.
J.Am.Chem.Soc., 135, 2013
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8RP6
 | | Aminodeoxychorismate synthase complex from Escherichia coli | | Descriptor: | Aminodeoxychorismate synthase component 1, Aminodeoxychorismate synthase component 2, CHLORIDE ION, ... | | Authors: | Sung, S, Funke, F.J, Schlee, S, Sterner, R, Wilmanns, M. | | Deposit date: | 2024-01-12 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Activity regulation of the aminodeoxychorismate synthase bienzyme complex by glutaminase substrate-mediated subunit interface expansion
To Be Published
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8RP0
 | | Aminodeoxychorismate synthase complex from Escherichia coli, with glutamine and chorismate added | | Descriptor: | (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, Aminodeoxychorismate synthase component 1, Aminodeoxychorismate synthase component 2, ... | | Authors: | Sung, S, Funke, F.J, Schlee, S, Sterner, R, Wilmanns, M. | | Deposit date: | 2024-01-12 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Activity regulation of the aminodeoxychorismate synthase bienzyme complex by glutaminase substrate-mediated subunit interface expansion
To Be Published
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8RP1
 | | Aminodeoxychorismate synthase complex from Escherichia coli, with glutamine added | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aminodeoxychorismate synthase component 1, Aminodeoxychorismate synthase component 2, ... | | Authors: | Sung, S, Franziska, J.F, Schlee, S, Sterner, R, Wilmanns, M. | | Deposit date: | 2024-01-12 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Activity regulation of the aminodeoxychorismate synthase bienzyme complex by glutaminase substrate-mediated subunit interface expansion
To Be Published
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8RP2
 | | Aminodeoxychorismate synthase complex from Escherichia coli, with EDTA added | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aminodeoxychorismate synthase component 1, Aminodeoxychorismate synthase component 2, ... | | Authors: | Sung, S, Funke, F.J, Schlee, S, Sterner, R, Wilmanns, M. | | Deposit date: | 2024-01-12 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Activity regulation of the aminodeoxychorismate synthase bienzyme complex by glutaminase substrate-mediated subunit interface expansion
To Be Published
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8RP7
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4J5N
 | | Crystal Structure of a Deinococcus radiodurans PTE-like lactonase (drPLL) mutant Y28L/D71N/E101G/E179D/V235L/L270M | | Descriptor: | COBALT (II) ION, Phosphotriesterase, putative | | Authors: | Meier, M.M, Rajendran, C, Malisi, C, Fox, N.G, Xu, C, Schlee, S, Barondeau, D.P, Hocker, B, Sterner, R, Raushel, F.M. | | Deposit date: | 2013-02-08 | | Release date: | 2013-07-24 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.
J.Am.Chem.Soc., 135, 2013
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4EVZ
 | | Structure of HisF-LUCA | | Descriptor: | HYDROGENPHOSPHATE ION, HisF-LUCA | | Authors: | Reisinger, B, Sperl, J, Rajendran, C, Merkl, R, Sterner, R. | | Deposit date: | 2012-04-26 | | Release date: | 2013-11-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.462 Å) | | Cite: | Evidence for the existence of elaborate enzyme complexes in the Paleoarchean era.
J.Am.Chem.Soc., 136, 2014
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4J2M
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6R8X
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6FFS
 | | Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors | | Descriptor: | 3C Protease, SULFATE ION, ~{N}-[(2~{S},5~{S},14~{S})-2-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-9-methyl-3,8,15-tris(oxidanylidene)-1,4,9-triazacyclopentadec-14-yl]-5-methyl-1,2-oxazole-3-carboxamide | | Authors: | Wiesmann, C, Farady, C. | | Deposit date: | 2018-01-09 | | Release date: | 2018-02-21 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors.
Bioorg. Med. Chem. Lett., 28, 2018
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6FFN
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