6GK2
 
 | | Helical reconstruction of BCL10 CARD and MALT1 DEATH DOMAIN complex | | Descriptor: | B-cell lymphoma/leukemia 10, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | | Authors: | Schlauderer, F, Desfosses, A, Gutsche, I, Hopfner, K.P, Lammens, K. | | Deposit date: | 2018-05-18 | | Release date: | 2018-10-31 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Molecular architecture and regulation of BCL10-MALT1 filaments.
Nat Commun, 9, 2018
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4I1R
 | | Human MALT1 (caspase-IG3) in complex with thioridazine | | Descriptor: | 10-{2-[(2S)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | | Authors: | Schlauderer, F, Lammens, K, Hopfner, K.P. | | Deposit date: | 2012-11-21 | | Release date: | 2013-08-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Analysis of Phenothiazine Derivatives as Allosteric Inhibitors of the MALT1 Paracaspase.
Angew.Chem.Int.Ed.Engl., 52, 2013
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4I1P
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7NT4
 | | X-ray structure of SCoV2-PLpro in complex with small molecule inhibitor | | Descriptor: | 1,2-ETHANEDIOL, Non-structural protein 3, PROFLAVIN, ... | | Authors: | Napolitano, V, Mourao, A, Bostock, M, Matsuda, A, Czarna, A, Popowicz, G.M. | | Deposit date: | 2021-03-09 | | Release date: | 2022-02-02 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses.
Cell Chem Biol, 29, 2022
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4FBQ
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4FBK
 | | Crystal structure of a covalently fused Nbs1-Mre11 complex with one manganese ion per active site | | Descriptor: | DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION, SULFATE ION | | Authors: | Schiller, C.B, Lammens, K, Hopfner, K.P. | | Deposit date: | 2012-05-23 | | Release date: | 2012-06-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.379 Å) | | Cite: | Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
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4FCX
 | | S.pombe Mre11 apoenzym | | Descriptor: | DNA repair protein rad32, MANGANESE (II) ION | | Authors: | Schiller, C.B, Lammens, K, Hopfner, K.P. | | Deposit date: | 2012-05-25 | | Release date: | 2012-06-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
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4FBW
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