3EYM
 
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.A, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2008-10-21 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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3EYJ
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | 分子名称: | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinahuer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2008-10-21 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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3EYK
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2008-10-21 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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1TI8
 | | H7 Haemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... | | 著者 | Russell, R.J, Gamblin, S.J, Haire, L.F, Stevens, D.J, Xaio, B, Ha, Y, Skehel, J.J. | | 登録日 | 2004-06-02 | | 公開日 | 2005-06-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes.
Virology, 325, 2004
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2HT8
 | | N8 neuraminidase in complex with oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTQ
 | | N8 neuraminidase in complex with zanamivir | | 分子名称: | Neuraminidase, ZANAMIVIR | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTV
 | | N4 neuraminidase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HT5
 | | N8 Neuraminidase | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTR
 | | N8 neuraminidase in complex with DANA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HT7
 | | N8 neuraminidase in open complex with oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTU
 | | N8 neuraminidase in complex with peramivir | | 分子名称: | 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTW
 | | N4 neuraminidase in complex with DANA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HU0
 | | N1 neuraminidase in complex with oseltamivir 1 | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HTY
 | | N1 neuraminidase | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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2HU4
 | | N1 neuraminidase in complex with oseltamivir 2 | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | 著者 | Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-05 | | 最終更新日 | 2018-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
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3O9K
 | | Influenza NA in complex with compound 6 | | 分子名称: | 5-acetamido-2,6-anhydro-3,5-dideoxy-3-[(2E)-3-(4-methylphenyl)prop-2-en-1-yl]-D-glycero-D-galacto-non-2-enonic acid, Neuraminidase | | 著者 | Russell, R.J, Kerry, P.S. | | 登録日 | 2010-08-04 | | 公開日 | 2010-12-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4945 Å) | | 主引用文献 | Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
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3O9J
 | | Influenza NA in complex with compound 5 | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 5-acetamido-2,6-anhydro-3,5-dideoxy-3-prop-2-en-1-yl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | | 著者 | Russell, R.J, Kerry, P.S. | | 登録日 | 2010-08-04 | | 公開日 | 2010-12-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.0002 Å) | | 主引用文献 | Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
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3H96
 | | Msmeg_3358 F420 Reductase | | 分子名称: | 1,2-ETHANEDIOL, F420-H2 Dependent Reductase A | | 著者 | Jackson, C.J, French, N, Newman, J, Taylor, M.C, Russell, R.J, Oakeshott, J.G. | | 登録日 | 2009-04-30 | | 公開日 | 2010-04-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification and characterization of two families of F420 H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation.
Mol.Microbiol., 78, 2010
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3L4Q
 | | Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein | | 分子名称: | GLYCEROL, Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta | | 著者 | Hale, B.G, Kerry, P.S, Jackson, D, Precious, B.L, Gray, A, Killip, M.J, Randall, R.E, Russell, R.J. | | 登録日 | 2009-12-21 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein
Proc.Natl.Acad.Sci.USA, 107, 2010
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3CKZ
 | | N1 Neuraminidase H274Y + Zanamivir | | 分子名称: | CALCIUM ION, Neuraminidase, ZANAMIVIR | | 著者 | Colllins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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3CL2
 | | N1 Neuraminidase N294S + Oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | 著者 | Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2018-08-22 | | 実験手法 | X-RAY DIFFRACTION (2.538 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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3CL0
 | | N1 Neuraminidase H274Y + oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | | 著者 | Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2018-08-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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3D6R
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2WR7
 | | the structure of influenza H2 human singapore hemagglutinin with human receptor | | 分子名称: | HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose | | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2009-08-30 | | 公開日 | 2009-09-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2WRD
 | | structure of H2 japan hemagglutinin | | 分子名称: | HEMAGGLUTININ | | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2009-09-01 | | 公開日 | 2009-09-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
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