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Crystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS site
Descriptor:	Bifunctional dihydrofolate reductase-thymidylate synthase, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Czyzyk, D.J, Ruiz, V.G, Kumar, V.P, Jorgensen, W.L, Anderson, K.S.
Deposit date:	2020-04-02
Release date:	2020-06-17
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.79 Å)
Cite:	Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitor Bioorg.Med.Chem.Lett., 30, 2020

Crystal structure of Plasmodium falciparum MIF in complex with 3-[(2-methyl-6-phenylpyridin-4-yl)oxy]phenol
Descriptor:	3-[(2-methyl-6-phenylpyridin-4-yl)oxy]phenol, Macrophage migration inhibitory factor-like protein
Authors:	Pantouris, G, Lolis, E.
Deposit date:	2014-03-27
Release date:	2014-10-15
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (3.02 Å)
Cite:	Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors. J.Med.Chem., 57, 2014

Crystal structure of PfMIF in complex with 4-(3-methoxy-5-methylphenoxy)-2-(4-methoxyphenyl)-6-methylpyridine
Descriptor:	4-(3-methoxy-5-methylphenoxy)-2-(4-methoxyphenyl)-6-methylpyridine, Macrophage migration inhibitory factor-like protein
Authors:	Pantouris, G, Lolis, E.
Deposit date:	2014-03-27
Release date:	2014-10-15
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.87 Å)
Cite:	Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors. J.Med.Chem., 57, 2014