2WR6
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![BU of 2wr6 by Molmil](/molmil-images/mine/2wr6) | Structure of the complex of RBP4 with linoleic acid | Descriptor: | (11E,13E,15Z)-OCTADECA-11,13,15-TRIENOIC ACID, CHLORIDE ION, RETINOL-BINDING PROTEIN 4 | Authors: | Huang, H.-J, Nanao, M, Stout, T, Rosen, J. | Deposit date: | 2009-08-29 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of a Non-Retinoid Compound and Fatty Acids as Ligands for Retinol Binding Protein 4 and Their Implications in Diabetes To be Published
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1L2T
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![BU of 1l2t by Molmil](/molmil-images/mine/1l2t) | Dimeric Structure of MJ0796, a Bacterial ABC Transporter Cassette | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Hypothetical ABC transporter ATP-binding protein MJ0796, ISOPROPYL ALCOHOL, ... | Authors: | Smith, P.C, Karpowich, N, Rosen, J, Hunt, J.F. | Deposit date: | 2002-02-24 | Release date: | 2002-07-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol.Cell, 10, 2002
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4RV7
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![BU of 4rv7 by Molmil](/molmil-images/mine/4rv7) | Characterization of an essential diadenylate cyclase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Diadenylate cyclase, HEXANE-1,6-DIOL, ... | Authors: | Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2014-11-25 | Release date: | 2015-01-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and Biochemical Analysis of the Essential Diadenylate Cyclase CdaA from Listeria monocytogenes. J.Biol.Chem., 290, 2015
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2A4L
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![BU of 2a4l by Molmil](/molmil-images/mine/2a4l) | |
1DM2
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![BU of 1dm2 by Molmil](/molmil-images/mine/1dm2) | HUMAN CYCLIN-DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR HYMENIALDISINE | Descriptor: | 1,2-ETHANEDIOL, 4-(5-AMINO-4-OXO-4H-PYRAZOL-3-YL)-2-BROMO-4,5,6,7-TETRAHYDRO-3AH-PYRROLO[2,3-C]AZEPIN-8-ONE, CYCLIN-DEPENDENT KINASE 2 | Authors: | Thunnissen, A.M, Kim, S.-H. | Deposit date: | 1999-12-13 | Release date: | 2000-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent. Chem.Biol., 7, 2000
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1HCK
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![BU of 1hck by Molmil](/molmil-images/mine/1hck) | HUMAN CYCLIN-DEPENDENT KINASE 2 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, HUMAN CYCLIN-DEPENDENT KINASE 2, MAGNESIUM ION | Authors: | Schulze-Gahmen, U, De Bondt, H.L, Kim, S.-H. | Deposit date: | 1996-06-03 | Release date: | 1996-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J.Med.Chem., 39, 1996
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1AQ1
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![BU of 1aq1 by Molmil](/molmil-images/mine/1aq1) | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR STAUROSPORINE | Descriptor: | CYCLIN-DEPENDENT PROTEIN KINASE 2, STAUROSPORINE | Authors: | Endicott, J.A, Noble, M.E.M, Johnson, L.N, Lawrie, A, Tunnah, P, Brown, N.R. | Deposit date: | 1997-08-05 | Release date: | 1997-11-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2. Nat.Struct.Biol., 4, 1997
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1G5S
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![BU of 1g5s by Molmil](/molmil-images/mine/1g5s) | CRYSTAL STRUCTURE OF HUMAN CYCLIN DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH THE INHIBITOR H717 | Descriptor: | 2-[TRANS-(4-AMINOCYCLOHEXYL)AMINO]-6-(BENZYL-AMINO)-9-CYCLOPENTYLPURINE, CELL DIVISION PROTEIN KINASE 2 | Authors: | Dreyer, M.K, Borcherding, D.R, Dumont, J.A, Peet, N.P, Tsay, J.T, Wright, P.S, Bitonti, A.J, Shen, J, Kim, S.-H. | Deposit date: | 2000-11-02 | Release date: | 2001-11-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Crystal structure of human cyclin-dependent kinase 2 in complex with the adenine-derived inhibitor H717. J.Med.Chem., 44, 2001
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1HCL
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![BU of 1hcl by Molmil](/molmil-images/mine/1hcl) | HUMAN CYCLIN-DEPENDENT KINASE 2 | Descriptor: | HUMAN CYCLIN-DEPENDENT KINASE 2 | Authors: | Schulze-Gahmen, U, De Bondt, H.L, Kim, S.-H. | Deposit date: | 1996-06-03 | Release date: | 1996-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J.Med.Chem., 39, 1996
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1CKP
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![BU of 1ckp by Molmil](/molmil-images/mine/1ckp) | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B | Descriptor: | 1,2-ETHANEDIOL, PROTEIN (CYCLIN-DEPENDENT PROTEIN KINASE 2), PURVALANOL B | Authors: | Gray, N.S, Thunnissen, A.M.W.H, Schultz, P.G, Kim, S.H. | Deposit date: | 1998-07-14 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science, 281, 1998
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1OSM
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![BU of 1osm by Molmil](/molmil-images/mine/1osm) | OSMOPORIN (OMPK36) FROM KLEBSIELLA PNEUMONIAE | Descriptor: | DODECANE, OMPK36 | Authors: | Dutzler, R, Schirmer, T. | Deposit date: | 1999-01-08 | Release date: | 1999-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure and functional characterization of OmpK36, the osmoporin of Klebsiella pneumoniae. Structure Fold.Des., 7, 1999
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