7YWY
 
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6GBH
 | | Helicobacter pylori adhesin HopQ type II bound to the N-terminal domain of human CEACAM1 | | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, HopQ, SULFATE ION | | 著者 | Moonens, K, Kruse, T, Gerhard, M, Remaut, H. | | 登録日 | 2018-04-13 | | 公開日 | 2018-06-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Helicobacter pyloriadhesin HopQ disruptstransdimerization in human CEACAMs.
EMBO J., 37, 2018
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8OPR
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8PDZ
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7OJF
 | | CRYO-EM STRUCTURE OF SLYB13-BAMA FROM ESCHERICHIA COLI | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(~{E},3~{R})-3-dodecanoyloxytetradec-5-enoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(~{E},3~{R})-3-oxidanyltetradec-11-enoyl]amino]-4-[(~{E},3~{R})-3-oxidanyltetradec-5-enoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(~{E},3~{R})-3-tetradecanoyloxytetradec-7-enoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, GLYCEROL, ... | | 著者 | Nguyen, V.S, Remaut, H. | | 登録日 | 2021-05-14 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains
Nature, 2023
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4UV3
 | | Structure of the curli transport lipoprotein CsgG in its membrane- bound conformation | | 分子名称: | CURLI PRODUCTION ASSEMBLY/TRANSPORT COMPONENT CSGG | | 著者 | Goyal, P, Krasteva, P.V, Gerven, N.V, Gubellini, F, Broeck, I.V.D, Troupiotis-Tsailaki, A, Jonckheere, W, Pehau-Arnaudet, G, Pinkner, J.S, Chapman, M.R, Hultgren, S.J, Howorka, S, Fronzes, R, Remaut, H. | | 登録日 | 2014-08-04 | | 公開日 | 2014-09-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | | 主引用文献 | Structural and Mechanistic Insights Into the Bacterial Amyloid Secretion Channel Csgg.
Nature, 516, 2014
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4UV2
 | | Structure of the curli transport lipoprotein CsgG in a non-lipidated, pre-pore conformation | | 分子名称: | CURLI PRODUCTION TRANSPORT COMPONENT CSGG | | 著者 | Goyal, P, Krasteva, P.V, Gerven, N.V, Gubellini, F, Broeck, I.V.D, Troupiotis-Tsailaki, A, Jonckheere, W, Pehau-Arnaudet, G, Pinkner, J.S, Chapman, M.R, Hultgren, S.J, Howorka, S, Fronzes, R, Remaut, H. | | 登録日 | 2014-08-04 | | 公開日 | 2014-09-24 | | 最終更新日 | 2014-12-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and Mechanistic Insights Into the Bacterial Amyloid Secretion Channel Csgg.
Nature, 516, 2014
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8CN1
 | | hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1 | | 分子名称: | Disks large homolog 1, GLU-THR-GLU-VAL, SULFATE ION | | 著者 | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | | 登録日 | 2023-02-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Antiviral Res., 217, 2023
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8CN3
 | | hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1 | | 分子名称: | Disks large homolog 1, GLU-THR-GLU-VAL | | 著者 | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | | 登録日 | 2023-02-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Antiviral Res., 217, 2023
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4G0H
 | | Crystal structure of the N-terminal domain of Helicobacter pylori CagA protein | | 分子名称: | Cytotoxicity-associated immunodominant antigen | | 著者 | Kaplan-Turkoz, B, Remaut, H, Dian, C, Louche, A, Terradot, L. | | 登録日 | 2012-07-09 | | 公開日 | 2012-08-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural insights into Helicobacter pylori oncoprotein CagA interaction with beta 1 integrin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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1PG5
 | | CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS | | 分子名称: | Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION | | 著者 | De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J. | | 登録日 | 2003-05-27 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius.
J.Mol.Biol., 339, 2004
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4WEN
 | | Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V2 | | 分子名称: | Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC | | 著者 | Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H. | | 登録日 | 2014-09-10 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
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4WEM
 | | Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V1 | | 分子名称: | Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC, PHOSPHATE ION | | 著者 | Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H. | | 登録日 | 2014-09-10 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
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4WEU
 | | Co-complex structure of the F4 fimbrial adhesin FaeG variant ad with llama single domain antibody V3 | | 分子名称: | Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD | | 著者 | Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H. | | 登録日 | 2014-09-11 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
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3RFZ
 | | Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate | | 分子名称: | Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ... | | 著者 | Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G. | | 登録日 | 2011-04-07 | | 公開日 | 2011-06-01 | | 最終更新日 | 2012-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
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5AFO
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4W6W
 | | Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF6 | | 分子名称: | F18 fimbrial adhesin AC, NbFedF6 | | 著者 | Moonens, K, De Kerpel, M, Annelies, C, Cox, E, Pardon, E, Remaut, H, De Greve, H. | | 登録日 | 2014-08-21 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
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4W6X
 | | Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF7 | | 分子名称: | F18 fimbrial adhesin AC, Nanobody NbFedF7 | | 著者 | Moonens, K, De Kerpel, M, Coddens, A, Cox, E, Pardon, E, Remaut, H, De Greve, H. | | 登録日 | 2014-08-21 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
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5NWP
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6QD6
 | | Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207 | | 分子名称: | CHLORIDE ION, Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207 | | 著者 | Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkonig, A, Zogg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J. | | 登録日 | 2018-12-31 | | 公開日 | 2019-12-18 | | 最終更新日 | 2021-01-13 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
Nat.Methods, 18, 2021
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6QFA
 | | CryoEM structure of a beta3K279T GABA(A)R homomer in complex with histamine and megabody Mb25 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit beta-3, HISTAMINE, ... | | 著者 | Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkoening, A, Zoegg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J. | | 登録日 | 2019-01-09 | | 公開日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | | 主引用文献 | Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021
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6S0Y
 | | Nanobody targeting influenza A matrix protein 2 ectodomain (M2e) | | 分子名称: | M2e-VHH-23m, Matrix protein 2 | | 著者 | Van Molle, I, De Vlieger, D, Schepens, B, Remaut, H, Saelens, X. | | 登録日 | 2019-06-18 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Selective Engagement of Fc gamma RIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection.
Front Immunol, 10, 2019
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2W07
 | | Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF | | 分子名称: | CHAPERONE PROTEIN PAPD, MINOR PILIN SUBUNIT PAPF, SULFATE ION | | 著者 | Verger, D, Rose, R.J, Paci, E, Costakes, G, Daviter, T, Hultgren, S, Remaut, H, Ashcroft, A.E, Radford, S.E, Waksman, G. | | 登録日 | 2008-08-12 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Determinants of Polymerization Reactivity of the P Pilus Adaptor Subunit Papf.
Structure, 16, 2008
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5LP2
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6SI7
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