1L2Z
| CD2BP2-GYF domain in complex with proline-rich CD2 tail segment peptide | Descriptor: | CD2 ANTIGEN (CYTOPLASMIC TAIL)-BINDING PROTEIN 2, T-CELL SURFACE ANTIGEN CD2 | Authors: | Freund, C, Kuhne, R, Yang, H, Park, S, Reinherz, E.L, Wagner, G. | Deposit date: | 2002-02-26 | Release date: | 2002-11-20 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules Embo J., 21, 2002
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1NEZ
| The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Liu, Y, Xiong, Y, Naidenko, O.V, Liu, J.H, Zhang, R, Joachimiak, A, Kronenberg, M, Cheroutre, H, Reinherz, E.L, Wang, J.H. | Deposit date: | 2002-12-12 | Release date: | 2003-04-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of a TL/CD8alphaalpha Complex at 2.1 A resolution: Implications for modulation of T cell activation and memory Immunity, 18, 2003
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2JXB
| Structure of CD3epsilon-Nck2 first SH3 domain complex | Descriptor: | T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 | Authors: | Takeuchi, K, Yang, H, Ng, E, Park, S, Sun, Z.J, Reinherz, E.L, Wagner, G. | Deposit date: | 2007-11-09 | Release date: | 2008-09-23 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity. J.Mol.Biol., 380, 2008
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2ME4
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | Descriptor: | Envelope glycoprotein gp160 | Authors: | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | Deposit date: | 2013-09-20 | Release date: | 2013-10-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME1
| HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle | Descriptor: | Gp41 | Authors: | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | Deposit date: | 2013-09-20 | Release date: | 2013-10-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME2
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | Descriptor: | Envelope glycoprotein gp160 | Authors: | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | Deposit date: | 2013-09-20 | Release date: | 2013-10-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME3
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | Descriptor: | Envelope glycoprotein gp160 | Authors: | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | Deposit date: | 2013-09-20 | Release date: | 2013-10-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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7SC5
| Cytoplasmic tail deleted HIV Env trimer in nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Yang, S, Walz, T. | Deposit date: | 2021-09-27 | Release date: | 2022-11-09 | Last modified: | 2023-02-22 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack. Nat Commun, 13, 2022
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7SD3
| Cytoplasmic tail deleted HIV-1 Env bound with three 4E10 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4E10 Fab heavy chain, ... | Authors: | Yang, S, Walz, T. | Deposit date: | 2021-09-29 | Release date: | 2022-11-09 | Last modified: | 2023-02-22 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack. Nat Commun, 13, 2022
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1CDB
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1GYA
| N-GLYCAN AND POLYPEPTIDE NMR SOLUTION STRUCTURES OF THE ADHESION DOMAIN OF HUMAN CD2 | Descriptor: | HUMAN CD2, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Wyss, D.F, Choi, J.S, Wagner, G. | Deposit date: | 1995-05-26 | Release date: | 1996-11-08 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | Conformation and function of the N-linked glycan in the adhesion domain of human CD2. Science, 269, 1995
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5WDF
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3H3P
| Crystal structure of HIV epitope-scaffold 4E10 Fv complex | Descriptor: | 4E10_S0_1TJLC_004_N, CALCIUM ION, Fv 4E10 heavy chain, ... | Authors: | Holmes, M.A. | Deposit date: | 2009-04-16 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity J.Virol., 84, 2010
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3Q5Y
| V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Chen, Q, Zhang, H, Wang, J.-H. | Deposit date: | 2010-12-30 | Release date: | 2011-03-09 | Last modified: | 2014-10-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A conserved hydrophobic patch on Vbeta domains revealed by TCRbeta chain crystal structures: implications for pre-TCR dimerization Front Immunol, 2, 2011
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3Q5T
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3CD4
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