3M3N
 
 | | Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Rebowski, G, Namgoong, S, Dominguez, R. | | Deposit date: | 2010-03-09 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (7 Å) | | Cite: | Structure of a longitudinal actin dimer assembled by tandem w domains: implications for actin filament nucleation.
J.Mol.Biol., 403, 2010
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7T5Q
 | | Cryo-EM Structure of a Transition State of Arp2/3 Complex Activation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Rebowski, G, van Eeuwen, T, Boczkowska, M, Dominguez, R. | | Deposit date: | 2021-12-13 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)
To Be Published
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4EDQ
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6NBE
 | | Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2018-12-07 | | Release date: | 2020-04-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
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6NBW
 | | Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2018-12-10 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
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6NAS
 | | Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2018-12-06 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
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4Z94
 | | Actin Complex With a Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2015-04-09 | | Release date: | 2015-10-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
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4Z79
 | | Leiomodin-1 Actin-Binding Site 2 (ABS2) | | Descriptor: | CHLORIDE ION, GLYCEROL, Leiomodin-1 Actin-Binding Site 2 (ABS2), ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2015-04-06 | | Release date: | 2015-10-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.
Nat Commun, 6, 2015
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7JPN
 | | Cryo-EM structure of Arpin-bound Arp2/3 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | Authors: | van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G. | | Deposit date: | 2020-08-09 | | Release date: | 2022-02-09 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Molecular mechanism of Arp2/3 complex inhibition by Arpin.
Nat Commun, 13, 2022
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4Z8G
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3OK8
 | | I-BAR OF PinkBAR | | Descriptor: | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2, GLYCEROL | | Authors: | Boczkowska, M, Rebowski, G, Saarikangas, J, Lappalainen, P, Dominguez, R. | | Deposit date: | 2010-08-24 | | Release date: | 2011-07-13 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures.
Nat.Struct.Mol.Biol., 18, 2011
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2PBD
 | | Ternary complex of profilin-actin with the poly-PRO-GAB domain of VASP* | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Ferron, F, Rebowski, G, Dominguez, R. | | Deposit date: | 2007-03-28 | | Release date: | 2007-11-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.501 Å) | | Cite: | Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP
Embo J., 26, 2007
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2PAV
 | | Ternary complex of Profilin-Actin with the Last Poly-Pro of Human VASP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Ferron, F, Rebowski, G, Dominguez, R. | | Deposit date: | 2007-03-27 | | Release date: | 2007-10-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.
Embo J., 26, 2007
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3M1F
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1N2D
 | | Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin | | Descriptor: | IQ2 AND IQ3 MOTIFS FROM MYO2P, A CLASS V MYOSIN, Myosin Light Chain | | Authors: | Terrak, M, Wu, G, Stafford, W.F, Lu, R.C, Dominguez, R. | | Deposit date: | 2002-10-22 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the light chain-binding domain of myosin V.
Proc.Natl.Acad.Sci.USA, 102, 2005
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5WFN
 | | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT) | | Descriptor: | Actin-5C, Leiomodin-2, MAGNESIUM ION, ... | | Authors: | Yurtsever, Z, Eck, M.J, Dominguez, R. | | Deposit date: | 2017-07-12 | | Release date: | 2017-08-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
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8TAH
 | | Cryo-EM structure of Cortactin-bound to Arp2/3 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | | Authors: | Fregoso, F.E, van Eeuwen, T, Dominguez, R. | | Deposit date: | 2023-06-27 | | Release date: | 2023-09-27 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins.
Nat Commun, 14, 2023
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6UHC
 | | CryoEM structure of human Arp2/3 complex with bound NPFs | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | Authors: | Zimmet, A, van Eeuwen, T, Dominguez, R. | | Deposit date: | 2019-09-27 | | Release date: | 2020-07-01 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
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3RYL
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3P53
 | | Structure of fascin | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, DODECAETHYLENE GLYCOL, Fascin, ... | | Authors: | Jansen, S, Dominguez, R. | | Deposit date: | 2010-10-07 | | Release date: | 2011-06-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanism of actin filament bundling by fascin.
J.Biol.Chem., 286, 2011
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2Q97
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8F8Q
 | | Cryo-EM structure of the CapZ-capped barbed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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8F8P
 | | Cryo-EM structure of F-actin in the ADP state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.26 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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8F8R
 | | Cryo-EM structure of the free barbed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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8F8T
 | | Cryo-EM structure of the Tropomodulin-capped pointed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | | Deposit date: | 2022-11-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structures of the free and capped ends of the actin filament.
Science, 380, 2023
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