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7OXD
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BU of 7oxd by Molmil
Crystal structure of Scytonema hofmanni transposition protein TniQ
Descriptor: ShTniQ, ZINC ION
Authors:Querques, I, Jinek, M.
Deposit date:2021-06-22
Release date:2021-12-01
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Target site selection and remodelling by type V CRISPR-transposon systems.
Nature, 599, 2021
7PLH
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BU of 7plh by Molmil
Scytonema hofmannii TnsC bound to AMPPNP and DNA
Descriptor: DNA (5'-D(P*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3'), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Querques, I, Jinek, M.
Deposit date:2021-08-31
Release date:2021-12-01
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Target site selection and remodelling by type V CRISPR-transposon systems.
Nature, 599, 2021
8BD4
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BU of 8bd4 by Molmil
TniQ-capped Tns-ATP-dsDNA complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*AP*TP*CP*GP*AP*TP*CP*GP*AP*TP*CP*GP*AP*TP*C)-3'), MAGNESIUM ION, ...
Authors:Querques, I, Schmitz, M, Oberli, S, Chanez, C, Jinek, M.
Deposit date:2022-10-18
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structural basis for the assembly of the type V CRISPR-associated transposon complex.
Cell, 185, 2022
8BD5
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BU of 8bd5 by Molmil
Cas12k-sgRNA-dsDNA-S15-TniQ-TnsC transposon recruitment complex
Descriptor: 30S ribosomal protein S15, ADENOSINE-5'-TRIPHOSPHATE, DNA non-target strand, ...
Authors:Schmitz, M, Querques, I, Oberli, S, Chanez, C, Jinek, M.
Deposit date:2022-10-18
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for the assembly of the type V CRISPR-associated transposon complex.
Cell, 185, 2022
8BD6
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BU of 8bd6 by Molmil
Cas12k-sgRNA-dsDNA-TnsC non-productive complex.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cas12k, DNA, ...
Authors:Schmitz, M, Querques, I, Oberli, S, Chanez, C, Jinek, M.
Deposit date:2022-10-18
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for the assembly of the type V CRISPR-associated transposon complex.
Cell, 185, 2022
7PLA
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BU of 7pla by Molmil
Cryo-EM structure of ShCas12k in complex with a sgRNA and a dsDNA target
Descriptor: DNA non-target strand, DNA target strand, ShCas12k, ...
Authors:Schmitz, M, Jinek, M.
Deposit date:2021-08-30
Release date:2021-12-01
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Target site selection and remodelling by type V CRISPR-transposon systems.
Nature, 599, 2021
5CR4
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BU of 5cr4 by Molmil
Crystal structure of the Sleeping Beauty transposase catalytic domain
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CITRIC ACID, GLYCEROL, ...
Authors:Voigt, F, Barabas, O.
Deposit date:2015-07-22
Release date:2016-03-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering.
Nat Commun, 7, 2016
7Z4E
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BU of 7z4e by Molmil
SpCas9 bound to 8-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 8 nucleotide complementary DNA substrate, Target strand of 8 nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4I
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BU of 7z4i by Molmil
SpCas9 bound to 16-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 16-nucleotide complementary DNA substrate, POTASSIUM ION, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4C
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BU of 7z4c by Molmil
SpCas9 bound to 6 nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 6 nucleotide complementary DNA substrate, Target strand of 6 nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4G
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BU of 7z4g by Molmil
SpCas9 bound to 12-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 12-nucleotide complementary DNA substrate, Target strand of 12-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4H
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BU of 7z4h by Molmil
SpCas9 bound to 14-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 14-nucleotide complementary DNA substrate, Target strand of 14-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4K
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BU of 7z4k by Molmil
SpCas9 bound to 10-nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 10-nucleotide complementary DNA substrate, Target strand of 10-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-04
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4J
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BU of 7z4j by Molmil
SpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic state
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4L
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BU of 7z4l by Molmil
SpCas9 bound to 18-nucleotide complementary DNA substrate in the checkpoint state
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-04
Release date:2022-08-31
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7Z4D
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BU of 7z4d by Molmil
Crystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 10 nucleotide complementary DNA substrate, POTASSIUM ION, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-03-03
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022

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PDB entries from 2024-08-07

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