6E0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e0g by Molmil](/molmil-images/mine/6e0g) | Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein | Descriptor: | mitochondrial 2-cys-peroxiredoxin | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | Deposit date: | 2018-07-06 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun, 10, 2019
|
|
6E0F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e0f by Molmil](/molmil-images/mine/6e0f) | Mitochondrial peroxiredoxin from Leishmania infantum in complex with unfolding client protein after heat stress | Descriptor: | mitochondrial 2-cys-peroxiredoxin | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | Deposit date: | 2018-07-06 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun, 10, 2019
|
|
1HYU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hyu by Molmil](/molmil-images/mine/1hyu) | CRYSTAL STRUCTURE OF INTACT AHPF | Descriptor: | ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Wood, Z.A, Poole, L.B, Karplus, P.A. | Deposit date: | 2001-01-22 | Release date: | 2001-02-14 | Last modified: | 2012-05-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of intact AhpF reveals a mirrored thioredoxin-like active site and implies large domain rotations during catalysis. Biochemistry, 40, 2001
|
|
4GQF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gqf by Molmil](/molmil-images/mine/4gqf) | Aeropyrum pernix Peroxiredoxin Q Enzyme in the Locally Unfolded Conformation | Descriptor: | GLYCEROL, SULFATE ION, Thiol peroxidase | Authors: | Perkins, A, Karplus, P.A, Gretes, M.C, Nelson, K.J, Poole, L.B. | Deposit date: | 2012-08-22 | Release date: | 2012-10-24 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mapping the Active Site Helix-to-Strand Conversion of CxxxxC Peroxiredoxin Q Enzymes. Biochemistry, 51, 2012
|
|
4GQC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gqc by Molmil](/molmil-images/mine/4gqc) | Crystal Structure of Aeropyrum pernix Peroxiredoxin Q Enzyme in Fully-Folded and Locally-Unfolded Conformations | Descriptor: | DITHIANE DIOL, GLYCEROL, SULFATE ION, ... | Authors: | Perkins, A, Karplus, P.A, Gretes, M.C, Nelson, K.J, Poole, L.B. | Deposit date: | 2012-08-22 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping the Active Site Helix-to-Strand Conversion of CxxxxC Peroxiredoxin Q Enzymes. Biochemistry, 51, 2012
|
|
1N8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1n8j by Molmil](/molmil-images/mine/1n8j) | |
5IPG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ipg by Molmil](/molmil-images/mine/5ipg) | Xanthomonas campestris Peroxiredoxin Q - Structure FFT-butyl (Hyperoxodized by t-butyl hydroperoxide) | Descriptor: | Bacterioferritin comigratory protein, SODIUM ION | Authors: | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | Deposit date: | 2016-03-09 | Release date: | 2016-09-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
|
|
5IMD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5imd by Molmil](/molmil-images/mine/5imd) | Xanthomonas campestris Peroxiredoxin Q - Structure F4 | Descriptor: | Bacterioferritin comigratory protein, FORMIC ACID, OXYGEN ATOM, ... | Authors: | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | Deposit date: | 2016-03-06 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
|
|
5INY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iny by Molmil](/molmil-images/mine/5iny) | Xanthomonas campestris Peroxiredoxin Q - Structure F8 | Descriptor: | Bacterioferritin comigratory protein, FORMIC ACID, SODIUM ION | Authors: | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | Deposit date: | 2016-03-08 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
|
|
5IOX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iox by Molmil](/molmil-images/mine/5iox) | Xanthomonas campestris Peroxiredoxin Q - Structure LUss | Descriptor: | Bacterioferritin comigratory protein | Authors: | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | Deposit date: | 2016-03-09 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
|
|
5IMV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5imv by Molmil](/molmil-images/mine/5imv) | Xanthomonas campestris Peroxiredoxin Q - Structure F6 | Descriptor: | Bacterioferritin comigratory protein, FORMIC ACID, SODIUM ION | Authors: | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | Deposit date: | 2016-03-07 | Release date: | 2016-09-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
|
|
4MAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mab by Molmil](/molmil-images/mine/4mab) | Resolving Cys to Ala variant of Salmonella Alkyl Hydroperoxide Reductase C in its substrate-ready conformation | Descriptor: | Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, GLYCEROL, ... | Authors: | Perkins, A, Nelson, K.J, Williams, J.R, Poole, L.B, Karplus, P.A. | Deposit date: | 2013-08-15 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin. Biochemistry, 52, 2013
|
|
4CW9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cw9 by Molmil](/molmil-images/mine/4cw9) | Entamoeba histolytica thiredoxin C34S mutant | Descriptor: | THIOREDOXIN | Authors: | Parsonage, D, Kells, P.M, Vieira, D.F, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M. | Deposit date: | 2014-04-01 | Release date: | 2015-05-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action. J.Struct.Biol., 194, 2016
|
|
4CCR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ccr by Molmil](/molmil-images/mine/4ccr) | Crystal structure of the thioredoxin reductase apoenzyme from Entamoeba histolytica in the absence of the NADP cofactor | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, THIOREDOXIN REDUCTASE | Authors: | Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M. | Deposit date: | 2013-10-25 | Release date: | 2014-11-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action. J.Struct.Biol., 194, 2016
|
|
4CBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cbq by Molmil](/molmil-images/mine/4cbq) | Crystal structure of the thioredoxin reductase from Entamoeba histolytica with auranofin Au(I) bound to Cys286 | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, ... | Authors: | Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M. | Deposit date: | 2013-10-16 | Release date: | 2014-11-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action. J.Struct.Biol., 194, 2016
|
|
4CCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ccq by Molmil](/molmil-images/mine/4ccq) | Crystal structure of the thioredoxin reductase from Entamoeba histolytica with NADP | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M. | Deposit date: | 2013-10-24 | Release date: | 2014-11-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action. J.Struct.Biol., 194, 2016
|
|
1YF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yf0 by Molmil](/molmil-images/mine/1yf0) | Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin. | Descriptor: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | Authors: | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | Deposit date: | 2004-12-29 | Release date: | 2005-08-16 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin. Biochemistry, 44, 2005
|
|
1XW4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xw4 by Molmil](/molmil-images/mine/1xw4) | Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Sulfiredoxin | Authors: | Murray, M.S, Jonsson, T.J, Johnson, L.C, Poole, L.B, Lowther, W.T. | Deposit date: | 2004-10-29 | Release date: | 2005-05-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. Biochemistry, 44, 2005
|
|
1YF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yf1 by Molmil](/molmil-images/mine/1yf1) | Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin. | Descriptor: | Alkyl hydroperoxide reductase subunit C, SODIUM ION | Authors: | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | Deposit date: | 2004-12-29 | Release date: | 2005-08-16 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin. Biochemistry, 44, 2005
|
|
1XW3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xw3 by Molmil](/molmil-images/mine/1xw3) | Crystal Structure of Human Sulfiredoxin (Srx) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, SULFIREDOXIN | Authors: | Murray, M.S, Jonsson, T.J, Johnson, L.C, Poole, L.B, Lowther, W.T. | Deposit date: | 2004-10-29 | Release date: | 2005-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. Biochemistry, 44, 2005
|
|
1YEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yep by Molmil](/molmil-images/mine/1yep) | Structural and biochemical analysis of the link between enzymatic activity and olgomerization in AhpC, a bacterial peroxiredoxin. | Descriptor: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | Authors: | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | Deposit date: | 2004-12-28 | Release date: | 2005-08-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin. Biochemistry, 44, 2005
|
|
1ZYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zyn by Molmil](/molmil-images/mine/1zyn) | Oxidized structure of the N-terminal domain of Salmonella typhimurium AhpF | Descriptor: | Alkyl hydroperoxide reductase subunit F | Authors: | Roberts, B.R, Wood, Z.A, Jonsson, T.J, Poole, L.B, Karplus, P.A. | Deposit date: | 2005-06-10 | Release date: | 2005-06-21 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF Protein Sci., 14, 2005
|
|
1ZYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zyp by Molmil](/molmil-images/mine/1zyp) | Synchrotron reduced form of the N-terminal domain of Salmonella typhimurium AhpF | Descriptor: | Alkyl hydroperoxide reductase subunit F | Authors: | Roberts, B.R, Wood, Z.A, Jonsson, T.J, Poole, L.B, Karplus, P.A. | Deposit date: | 2005-06-10 | Release date: | 2005-06-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF Protein Sci., 14, 2005
|
|
1YEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yex by Molmil](/molmil-images/mine/1yex) | Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin. | Descriptor: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | Authors: | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | Deposit date: | 2004-12-28 | Release date: | 2005-08-16 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin. Biochemistry, 44, 2005
|
|
5IMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ima by Molmil](/molmil-images/mine/5ima) | Xanthomonas campestris Peroxiredoxin Q - Structure F2 | Descriptor: | Bacterioferritin comigratory protein, FORMIC ACID, SODIUM ION | Authors: | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | Deposit date: | 2016-03-06 | Release date: | 2016-09-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
|
|