4CW9

Entamoeba histolytica thiredoxin C34S mutant

Summary for 4CW9

• Entry DOI: 10.2210/pdb4cw9/pdb
• Descriptor: THIOREDOXIN (2 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: ENTAMOEBA HISTOLYTICA HM-3\:IMSS
• Total number of polymer chains: 2
• Total formula weight: 24914.50

Authors

Parsonage, D.,Kells, P.M.,Vieira, D.F.,Hirata, K.,Debnath, A.,Poole, L.B.,McKerrow, J.H.,Reed, S.L.,Podust, L.M. (deposition date: 2014-04-01, release date: 2015-05-13, Last modification date: 2023-12-20)

• Primary citation: Parsonage, D.,Sheng, F.,Hirata, K.,Debnath, A.,Mckerrow, J.H.,Reed, S.L.,Abagyan, R.,Poole, L.B.,Podust, L.M.; X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action.; J.Struct.Biol., 194:180-, 2016; PubMed: 26876147; DOI: 10.1016/J.JSB.2016.02.015

Experimental method

X-RAY DIFFRACTION (1.84 Å)