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4FVM
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BU of 4fvm by Molmil
Crystal structure of yeast DNA polymerase alpha
Descriptor: DNA polymerase alpha catalytic subunit A
Authors:Perera, R.L, Pellegrini, L.
Deposit date:2012-06-29
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4FXD
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BU of 4fxd by Molmil
Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA
Descriptor: DNA (5'-D(*TP*TP*TP*TP*CP*GP*CP*TP*GP*CP*CP*CP*GP*CP*CP*T)-3'), DNA polymerase alpha catalytic subunit A, RNA (5'-R(*AP*GP*GP*CP*GP*GP*GP*CP*AP*G)-3')
Authors:Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L.
Deposit date:2012-07-03
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4FYD
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BU of 4fyd by Molmil
Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA and dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*GP*AP*GP*CP*GP*TP*G*TP*GP*TP*AP*CP*CP*CP*CP*TP*GP*CP*CP*CP*GP*CP*CP*G)-3'), DNA polymerase alpha catalytic subunit A, ...
Authors:Perera, R.L, Pellegrini, L.
Deposit date:2012-07-04
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4B08
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BU of 4b08 by Molmil
Yeast DNA polymerase alpha, Selenomethionine protein
Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A
Authors:Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L.
Deposit date:2012-06-29
Release date:2013-02-27
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha
Elife, 2, 2013
2XKJ
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BU of 2xkj by Molmil
CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE)
Descriptor: GLYCEROL, SULFATE ION, TOPOISOMERASE IV
Authors:Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D.
Deposit date:2010-07-08
Release date:2010-09-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
2XKK
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BU of 2xkk by Molmil
CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, and A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE)
Descriptor: 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA, MAGNESIUM ION, ...
Authors:Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D.
Deposit date:2010-07-08
Release date:2010-09-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
4BPU
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BU of 4bpu by Molmil
Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain.
Descriptor: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, GLYCEROL, ...
Authors:Kilkenny, M.L, Perera, R.L, Pellegrini, L.
Deposit date:2013-05-28
Release date:2013-09-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
4BPX
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BU of 4bpx by Molmil
Crystal structure of human primase in complex with the primase- binding motif of DNA polymerase alpha
Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT, DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, ...
Authors:Kilkenny, M.L, Perera, R.L, Pellegrini, L.
Deposit date:2013-05-28
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
4BPW
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BU of 4bpw by Molmil
Crystal structure of human primase bound to UTP
Descriptor: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, MAGNESIUM ION, ...
Authors:Kilkenny, M.L, Perera, R.L, Pellegrini, L.
Deposit date:2013-05-28
Release date:2013-09-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
3LGB
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BU of 3lgb by Molmil
Crystal Structure of the Fe-S Domain of the yeast DNA primase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA primase large subunit, GLYCEROL, ...
Authors:Sauguet, L, Pellegrini, L.
Deposit date:2010-01-20
Release date:2010-04-21
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase
PLOS ONE, 5, 2010
6I52
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BU of 6i52 by Molmil
Yeast RPA bound to ssDNA
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Replication factor A protein 1, Replication factor A protein 2, ...
Authors:Yates, L.A, Aramayo, R.J, Zhang, X.
Deposit date:2018-11-12
Release date:2018-12-19
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.
Nat Commun, 9, 2018
5NXQ
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BU of 5nxq by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP
Descriptor: DNA polymerase alpha-binding protein, GLYCEROL, MET-ASP-ILE-UA1-ILE-ASP-ASP-ILE-LEU-UA2-GLU-LEU-ASP-LYS-GLU
Authors:Wu, Y, Pellegrini, L.
Deposit date:2017-05-10
Release date:2017-08-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.
Angew. Chem. Int. Ed. Engl., 56, 2017
4C8H
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BU of 4c8h by Molmil
Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein.
Descriptor: CTF4
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase Alpha in the Eukaryotic Replisome
Nature, 510, 2014
4C93
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BU of 4c93 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha.
Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A, DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C95
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BU of 4c95 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA REPLICATION COMPLEX GINS PROTEIN SLD5
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C8S
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BU of 4c8s by Molmil
Crystal structure of the C-terminal region of yeast Ctf4
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
5HOG
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BU of 5hog by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
Descriptor: DNA polymerase alpha-binding protein, Dna2p
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.092 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5HOI
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BU of 5hoi by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2.
Descriptor: DNA polymerase alpha-binding protein, Topoisomerase 1-associated factor 2
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016

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PDB entries from 2024-10-30

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