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4J4X
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BU of 4j4x by Molmil
Crystal structure of GraVN
Descriptor: NP protein
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-05-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4W
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BU of 4j4w by Molmil
Crystal structure of BueVN
Descriptor: Nucleocapsid
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-05-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.661 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4Y
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BU of 4j4y by Molmil
Triple mutant GraVN
Descriptor: NP protein
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-06-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4U
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BU of 4j4u by Molmil
Pentamer SFTSVN
Descriptor: Nucleocapsid protein
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-05-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4FZ7
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BU of 4fz7 by Molmil
Crystal structure of spleen tyrosine kinase complexed with 6-((1R,2S)-2-Amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide
Descriptor: 6-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide, Tyrosine-protein kinase SYK
Authors:Kuglstatter, A, Slade, M.
Deposit date:2012-07-06
Release date:2013-07-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
J. Med. Chem., 57, 2014
5HXL
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BU of 5hxl by Molmil
Structure based function annotation of a hypothetical protein MGG_01005 related to the development of rice blast fungus
Descriptor: dynein light chain Tctex-1
Authors:Liu, J, Huang, J, Li, G, Peng, Y.
Deposit date:2016-01-31
Release date:2017-02-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3.
Sci Rep, 8, 2018
4TOT
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BU of 4tot by Molmil
Crystal structure of rat cyclophilin D in complex with a potent nonimmunosuppressive inhibitor
Descriptor: HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
Authors:Knapp, M.S, Elling, R.A.
Deposit date:2014-06-06
Release date:2014-11-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
J.Med.Chem., 57, 2014
6KK7
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BU of 6kk7 by Molmil
Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain
Descriptor: Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Authors:Song, G.
Deposit date:2019-07-23
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mutagenesis facilitated crystallization of GLP-1R.
Iucrj, 6, 2019
6KK1
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BU of 6kk1 by Molmil
Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain
Descriptor: Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Authors:Song, G.
Deposit date:2019-07-23
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutagenesis facilitated crystallization of GLP-1R.
Iucrj, 6, 2019
6KJV
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BU of 6kjv by Molmil
Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Authors:Song, G.
Deposit date:2019-07-23
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutagenesis facilitated crystallization of GLP-1R.
Iucrj, 6, 2019
5GRL
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BU of 5grl by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), isocitrate and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ISOCITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
Authors:Ma, T, Ding, J.
Deposit date:2016-08-11
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5GRF
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BU of 5grf by Molmil
Crystal structure of the alpha gamma mutant (gamma-K151A) of human IDH3 in complex with Mg(2+), citrate and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
Authors:Ma, T, Ding, J.
Deposit date:2016-08-11
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
7E9Q
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BU of 7e9q by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-03-04
Release date:2022-03-09
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7E9O
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BU of 7e9o by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(3 up RBDs, state2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-03-04
Release date:2022-03-09
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7E9P
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BU of 7e9p by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(state2, local refinement of the RBD and 35B5 Fab)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-03-04
Release date:2022-03-23
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7E9N
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BU of 7e9n by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-03-04
Release date:2022-04-06
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7ENG
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BU of 7eng by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30 (local refinement of the RBD and Fab30)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab30, Light chain of Fab30, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-04-16
Release date:2022-04-06
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7ENF
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BU of 7enf by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab30, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-04-16
Release date:2022-04-06
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7F46
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BU of 7f46 by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab (state1, local refinement of the RBD, NTD and 35B5 Fab)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-06-17
Release date:2022-03-23
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (4.79 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
5YOC
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BU of 5yoc by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond C102-R125C
Descriptor: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-27
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOG
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BU of 5yog by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond N14C-C93
Descriptor: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL, ...
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-27
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO4
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BU of 5yo4 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond K27C-A79C
Descriptor: Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-26
Release date:2018-03-14
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO5
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BU of 5yo5 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond A20C-Q25C
Descriptor: Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-26
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOE
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BU of 5yoe by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond A43C-L74C
Descriptor: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-27
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO3
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BU of 5yo3 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond V16C-A29C
Descriptor: SULFATE ION, Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-26
Release date:2018-05-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018

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数据于2024-05-15公开中

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