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2OCV
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BU of 2ocv by Molmil
Structural basis of Na+ activation mimicry in murine thrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin
著者Marino, F, Chen, Z, Ergenekan, C.E, Bush, L.A, Mathews, F.S, Di Cera, E.
登録日2006-12-21
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of na+ activation mimicry in murine thrombin.
J.Biol.Chem., 282, 2007
3QGN
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BU of 3qgn by Molmil
The allosteric E*-E equilibrium is a key property of the trypsin fold
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, IODIDE ION, ...
著者Niu, W, Gohara, D, Chen, Z, Di Cera, E.
登録日2011-01-24
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic and kinetic evidence of allostery in a trypsin-like protease.
Biochemistry, 50, 2011
3S7K
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BU of 3s7k by Molmil
Structure of thrombin mutant Y225P in the E form
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, POTASSIUM ION, Prothrombin
著者Niu, W, Chen, Z, Gandhi, P, Vogt, A, Pozzi, N, Pele, L.A, Zapata, F, Di Cera, E.
登録日2011-05-26
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease.
Biochemistry, 50, 2011
3S7H
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BU of 3s7h by Molmil
Structure of thrombin mutant Y225P in the E* form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Prothrombin
著者Niu, W, Chen, Z, Gandhi, P, Vogt, A, Pozzi, N, Pele, L.A, Zapata, F, Di Cera, E.
登録日2011-05-26
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease.
Biochemistry, 50, 2011
3SQH
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BU of 3sqh by Molmil
Crystal structure of prethrombin-2 mutant S195A in the the open form
分子名称: Thrombin light chain, heavy chain
著者Pozzi, N, Chen, Z, Di Cera, E.
登録日2011-07-05
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation.
Biochemistry, 50, 2011
3SQE
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BU of 3sqe by Molmil
Crystal structure of prethrombin-2 mutant S195A in the alternative form
分子名称: GLYCEROL, Thrombin light chain, heavy chain
著者Pozzi, N, Chen, Z, Di Cera, E.
登録日2011-07-05
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation.
Biochemistry, 50, 2011
5EDK
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BU of 5edk by Molmil
Crystal structure of prothrombin deletion mutant residues 146-167 ( Form II ).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ...
著者Pozzi, N, Chen, Z, Di Cera, E.
登録日2015-10-21
公開日2016-01-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.214 Å)
主引用文献How the Linker Connecting the Two Kringles Influences Activation and Conformational Plasticity of Prothrombin.
J.Biol.Chem., 291, 2016
4HZH
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BU of 4hzh by Molmil
Structure of recombinant Gla-domainless prothrombin mutant S525A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin
著者Pozzi, N, Niu, W, Gohara, D.W, Chen, Z, Di Cera, E.
登録日2012-11-15
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of prothrombin reveals conformational flexibility and mechanism of activation.
J.Biol.Chem., 288, 2013
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