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6C7O
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BU of 6c7o by Molmil
Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form
Descriptor: Apocarotenoid-15,15'-oxygenase, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-23
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
6C7K
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BU of 6c7k by Molmil
Crystal structure of an ACO/RPE65 chimera
Descriptor: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-22
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
6C7P
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BU of 6c7p by Molmil
Crystal structure of D477G ACO/RPE65 chimera, monoclinic crystal form
Descriptor: Apocarotenoid-15,15'-oxygenase, FE (II) ION
Authors:Kiser, P.D, Shi, W.
Deposit date:2018-01-23
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
2GGZ
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BU of 2ggz by Molmil
Crystal Structure of Human Guanylate Cyclase Activating Protein-3
Descriptor: CALCIUM ION, Guanylyl cyclase-activating protein 3
Authors:Stephen, R.
Deposit date:2006-03-24
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP-linked Cone Dystrophies.
J.Mol.Biol., 359, 2006
3C4W
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BU of 3c4w by Molmil
Crystal Structure of G protein coupled receptor kinase 1 bound to ATP and magnesium chloride at 2.7A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Singh, P, Tesmer, J.J.G.
Deposit date:2008-01-30
Release date:2008-03-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation.
J.Biol.Chem., 283, 2008
3C4Z
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BU of 3c4z by Molmil
Crystal structure of G protein coupled receptor kinase 1 bound to ADP and magnesium chloride at 1.84A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Singh, P, Tesmer, J.J.G.
Deposit date:2008-01-30
Release date:2008-03-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation.
J.Biol.Chem., 283, 2008
3C50
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BU of 3c50 by Molmil
Crystal Structure of G protein coupled receptor kinase 1 bound to ADP and magnesium chloride at 2.6A
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Singh, P, Tesmer, J.J.G.
Deposit date:2008-01-30
Release date:2008-03-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation.
J.Biol.Chem., 283, 2008
7K88
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BU of 7k88 by Molmil
Crystal structure of bovine RPE65 in complex with hexaethylene glycol monooctyl ether
Descriptor: 3,6,9,12,15,18-hexaoxahexacosan-1-ol, FE (II) ION, Retinoid isomerohydrolase, ...
Authors:Kiser, P.D.
Deposit date:2020-09-26
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
7K8G
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BU of 7k8g by Molmil
Crystal structure of bovine RPE65 in complex with 4-fluoro-MB-004 and palmitate
Descriptor: (1R)-3-amino-1-{4-fluoro-3-[(2-propylpentyl)oxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D.
Deposit date:2020-09-27
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
7K89
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BU of 7k89 by Molmil
Crystal structure of bovine RPE65 in complex with 4-fluoro-emixustat and palmitate
Descriptor: (1R)-3-amino-1-[3-(cyclohexylmethoxy)-4-fluorophenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D.
Deposit date:2020-09-26
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
7L0E
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BU of 7l0e by Molmil
Crystal structure of bovine RPE65 in complex with gem-difluoro emixustat and palmitate
Descriptor: (1R)-3-amino-1-{3-[(4,4-difluorocyclohexyl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D.
Deposit date:2020-12-11
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
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