1TNS
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1Y5O
| NMR structure of the amino-terminal domain from the Tfb1 subunit of yeast TFIIH | Descriptor: | RNA polymerase II transcription factor B 73 kDa subunit | Authors: | Di Lello, P, Nguyen, B.D, Jones, T.N, Potempa, K, Kobor, M.S, Legault, P, Omichinski, J.G. | Deposit date: | 2004-12-02 | Release date: | 2005-05-17 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | NMR Structure of the Amino-Terminal Domain from the Tfb1 Subunit of TFIIH and
Characterization of Its Phosphoinositide and VP16 Binding Sites Biochemistry, 44, 2005
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5C17
| Crystal structure of the mercury-bound form of MerB2 | Descriptor: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, MERCURY (II) ION, ... | Authors: | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2015-06-13 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry, 55, 2016
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5C0U
| Crystal structure of the copper-bound form of MerB mutant D99S | Descriptor: | Alkylmercury lyase, BROMIDE ION, COPPER (II) ION | Authors: | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2015-06-12 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry, 55, 2016
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5C0T
| Crystal structure of the mercury-bound form of MerB mutant D99S | Descriptor: | Alkylmercury lyase, BROMIDE ION, MERCURY (II) ION | Authors: | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2015-06-12 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry, 55, 2016
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5DSF
| Crystal structure of the mercury-bound form of MerB mutant D99S | Descriptor: | Alkylmercury lyase, BROMIDE ION, MERCURY (II) ION | Authors: | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2015-09-17 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.954 Å) | Cite: | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry, 55, 2016
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3F0P
| Crystal structure of the mercury-bound form of MerB, the Organomercurial Lyase involved in a bacterial mercury resistance system | Descriptor: | Alkylmercury lyase, BROMIDE ION, MERCURY (II) ION | Authors: | Lafrance-Vanasse, J, Lefebvre, M, Di Lello, P, Sygusch, J, Omichinski, J.G. | Deposit date: | 2008-10-25 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION J.Biol.Chem., 284, 2009
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3F0O
| Crystal structure of MerB, the Organomercurial Lyase involved in a bacterial mercury resistance system | Descriptor: | Alkylmercury lyase, BROMIDE ION | Authors: | Lafrance-Vanasse, J, Lefebvre, M, Di Lello, P, Sygusch, J, Omichinski, J.G. | Deposit date: | 2008-10-25 | Release date: | 2008-11-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION J.Biol.Chem., 284, 2009
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3F2H
| Crystal structure of the mercury-bound form of MerB mutant C160S, the Organomercurial Lyase involved in a bacterial mercury resistance system | Descriptor: | Alkylmercury lyase, MERCURY (II) ION | Authors: | Lafrance-Vanasse, J, Lefebvre, M, Di Lello, P, Sygusch, J, Omichinski, J.G. | Deposit date: | 2008-10-29 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION J.Biol.Chem., 284, 2009
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3F2G
| Crystal structure of MerB mutant C160S, the Organomercurial Lyase involved in a bacterial mercury resistance system | Descriptor: | Alkylmercury lyase | Authors: | Lafrance-Vanasse, J, Lefebvre, M, Di Lello, P, Sygusch, J, Omichinski, J.G. | Deposit date: | 2008-10-29 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.781 Å) | Cite: | Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION J.Biol.Chem., 284, 2009
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1S6L
| Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system | Descriptor: | Alkylmercury lyase | Authors: | Di Lello, P, Benison, G.C, Valafar, H, Pitts, K.E, Summers, A.O, Legault, P, Omichinski, J.G. | Deposit date: | 2004-01-25 | Release date: | 2005-04-19 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system. Biochemistry, 43, 2004
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3F2F
| Crystal structure of the mercury-bound form of MerB, the Organomercurial Lyase involved in a bacterial mercury resistance system | Descriptor: | Alkylmercury lyase, BROMIDE ION, MERCURY (II) ION | Authors: | Lafrance-Vanasse, J, Lefebvre, M, Di Lello, P, Sygusch, J, Omichinski, J.G. | Deposit date: | 2008-10-29 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION J.Biol.Chem., 284, 2009
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2MBH
| NMR structure of EKLF(22-40)/Ubiquitin Complex | Descriptor: | Krueppel-like factor 1, Ubiquitin | Authors: | Raiola, L, Omichinski, J.G. | Deposit date: | 2013-07-31 | Release date: | 2013-10-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Characterization of a Noncovalent Complex between Ubiquitin and the Transactivation Domain of the Erythroid-Specific Factor EKLF. Structure, 21, 2013
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2M14
| NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and Rad4 | Descriptor: | DNA repair protein RAD4, RNA polymerase II transcription factor B subunit 1 | Authors: | Lafrance-Vanasse, J, Arseneault, G, Cappadocia, L, Legault, P, Omichinski, J.G. | Deposit date: | 2012-11-16 | Release date: | 2013-01-23 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER. Nucleic Acids Res., 41, 2013
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2N0Y
| NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH | Descriptor: | Non-structural protein NS-S, RNA polymerase II transcription factor B subunit 1 | Authors: | Cyr, N, de la Fuente, C, Lecoq, L, Guendel, I, Chabot, P.R, Kehn-Hall, K, Omichinski, J.G. | Deposit date: | 2015-03-18 | Release date: | 2015-04-22 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Omega XaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence. Proc.Natl.Acad.Sci.USA, 112, 2015
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2GS0
| NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53 | Descriptor: | Cellular tumor antigen p53, RNA polymerase II transcription factor B subunit 1 | Authors: | Di Lello, P, Jones, T.N, Nguyen, B.D, Legault, P, Omichinski, J.G. | Deposit date: | 2006-04-25 | Release date: | 2006-10-31 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol.Cell, 22, 2006
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2K2U
| NMR Structure of the complex between Tfb1 subunit of TFIIH and the activation domain of VP16 | Descriptor: | Alpha trans-inducing protein, RNA polymerase II transcription factor B subunit 1 | Authors: | Langlois, C, Mas, C, Di Lello, P, Miller Jenkins, P.M, Legault, J, Omichinski, J.G. | Deposit date: | 2008-04-11 | Release date: | 2008-08-12 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53. J.Am.Chem.Soc., 130, 2008
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2JTX
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2KDT
| PC1/3 DCSG sorting domain structure in DPC | Descriptor: | Neuroendocrine convertase 1 | Authors: | Dikeakos, J.D, Di Lello, P, Lacombe, M.J, Ghirlando, R, Legault, P, Reudelhuber, T.L, Omichinski, J.G. | Deposit date: | 2009-01-19 | Release date: | 2009-04-07 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease. Proc.Natl.Acad.Sci.USA, 106, 2009
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2K7L
| NMR structure of a complex formed by the C-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 | Descriptor: | General transcription factor IIF subunit 1, centFCP1-T584PO4 peptide | Authors: | Yang, A, Abbott, K.L, Desjardins, A, Di Lello, P, Omichinski, J.G, Legault, P. | Deposit date: | 2008-08-13 | Release date: | 2009-06-02 | Last modified: | 2020-02-19 | Method: | SOLUTION NMR | Cite: | NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase Biochemistry, 48, 2009
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2KE3
| PC1/3 DCSG sorting domain in CHAPS | Descriptor: | Neuroendocrine convertase 1 | Authors: | Dikeakos, J.D, Di Lello, P, Lacombe, M.J, Ghirlando, R, Legault, P, Reudelhuber, T.L, Omichinski, J.G. | Deposit date: | 2009-01-22 | Release date: | 2009-04-14 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease Proc.Natl.Acad.Sci.USA, 106, 2009
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2L2I
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5SXP
| STRUCTURAL BASIS FOR THE INTERACTION BETWEEN ITCH PRR AND BETA-PIX | Descriptor: | E3 ubiquitin-protein ligase Itchy homolog, Rho guanine nucleotide exchange factor 7 | Authors: | Cappadocia, L, Desrochers, G, Lussier-Price, M, Angers, A, Omichinski, J.G. | Deposit date: | 2016-08-09 | Release date: | 2017-03-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular basis of interactions between SH3 domain-containing proteins and the proline-rich region of the ubiquitin ligase Itch. J. Biol. Chem., 292, 2017
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5U7A
| Crystal structure of a complex formed between MerB and Dimethyltin | Descriptor: | Alkylmercury lyase, BROMIDE ION, Dimethyltin dibromide, ... | Authors: | Wahba, H.M, Stevenson, M, Mansour, A, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2016-12-12 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.532 Å) | Cite: | Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage. J. Am. Chem. Soc., 139, 2017
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5U88
| Crystal structure of a MerB-triimethyllead complex. | Descriptor: | ACETATE ION, Alkylmercury lyase, Trimethyllead bromide | Authors: | Wahba, H.M, Stevenson, M, Mansour, A, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2016-12-14 | Release date: | 2017-01-11 | Last modified: | 2022-04-27 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage. J. Am. Chem. Soc., 139, 2017
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