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2KDT

PC1/3 DCSG sorting domain structure in DPC

Summary for 2KDT
Entry DOI10.2210/pdb2kdt/pdb
DescriptorNeuroendocrine convertase 1 (1 entity in total)
Functional Keywordssecretory granules, prohorme convertase, calcium, cleavage on pair of basic residues, cytoplasmic vesicle, glycoprotein, hydrolase, protease, serine protease, zymogen, protein transport
Biological sourceMus musculus (mouse)
Cellular locationCytoplasmic vesicle, secretory vesicle: P63239
Total number of polymer chains1
Total formula weight5275.73
Authors
Dikeakos, J.D.,Di Lello, P.,Lacombe, M.J.,Ghirlando, R.,Legault, P.,Reudelhuber, T.L.,Omichinski, J.G. (deposition date: 2009-01-19, release date: 2009-04-07, Last modification date: 2022-03-16)
Primary citationDikeakos, J.D.,Di Lello, P.,Lacombe, M.J.,Ghirlando, R.,Legault, P.,Reudelhuber, T.L.,Omichinski, J.G.
Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease.
Proc.Natl.Acad.Sci.USA, 106:7408-7413, 2009
Cited by
PubMed: 19376969
DOI: 10.1073/pnas.0809576106
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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