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8ACI
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BU of 8aci by Molmil
Structure of ARG-117 Fab in complex with a fragment of complement C2, neutral pH
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ARGX-117 Fab heavy chain, ARGX-117 Fab light chain, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2022-07-05
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
8ACF
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BU of 8acf by Molmil
Structure of the argX-117 in complex with a complement C2 fragment at low pH
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2022-07-05
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
7Q6C
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BU of 7q6c by Molmil
complement C6 FIM1-2 bound to CP010 antibody
Descriptor: ACETATE ION, CP010 heavy chain, CP010 light chain, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2021-11-06
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.29274 Å)
Cite:Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
J Innate Immun, 2022
6XZU
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BU of 6xzu by Molmil
Complex of C-terminal domain of murine complement C3b with the hC3Nb3 nanobody
Descriptor: Complement C3, nanobody hC3Nb1
Authors:Andersen, G.R, Pedersen, H.
Deposit date:2020-02-05
Release date:2020-08-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
J Immunol., 205, 2020
6YSQ
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BU of 6ysq by Molmil
The hC4Nb8 complement inhibitory nanobody in complex with C4b
Descriptor: Complement C4 beta chain, Complement C4 gamma chain, Complement C4-A alpha chain, ...
Authors:Zarantonello, A, Laursen, N.S, Andersen, G.R.
Deposit date:2020-04-23
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase.
J Immunol., 205, 2020

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PDB entries from 2024-06-12

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