2EH9
 
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5YVB
 | | Structure of CaMKK2 in complex with CKI-011 | | 分子名称: | (3Z)-5-chloro-3-[(1-methyl-1H-pyrazol-4-yl)methylidene]-1,3-dihydro-2H-indol-2-one, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | | 著者 | Niwa, H, Handa, N, Yokoyama, S. | | 登録日 | 2017-11-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
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5YV9
 | | Structure of CaMKK2 in complex with CKI-009 | | 分子名称: | 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | | 著者 | Niwa, H, Handa, N, Yokoyama, S. | | 登録日 | 2017-11-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
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5YVA
 | | Structure of CaMKK2 in complex with CKI-010 | | 分子名称: | 3-(1H-tetrazol-5-yl)-10lambda~6~-thioxanthene-9,10,10-trione, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | | 著者 | Niwa, H, Handa, N, Yokoyama, S. | | 登録日 | 2017-11-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2020-06-10 | | 実験手法 | X-RAY DIFFRACTION (2.574 Å) | | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
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5YV8
 | | Structure of CaMKK2 in complex with CKI-002 | | 分子名称: | 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | | 著者 | Niwa, H, Handa, N, Yokoyama, S. | | 登録日 | 2017-11-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.927 Å) | | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
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5YVC
 | | Structure of CaMKK2 in complex with CKI-012 | | 分子名称: | 3-{2,4-dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | | 著者 | Niwa, H, Handa, N, Yokoyama, S. | | 登録日 | 2017-11-24 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
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4EIW
 | | Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH | | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Yoshida, M, Morikawa, K. | | 登録日 | 2012-04-06 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structure of the whole cytosolic region of ATP-dependent protease FtsH
Mol.Cell, 22, 2006
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5WRM
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide | | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1 | | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | 登録日 | 2016-12-02 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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2DHR
 | | Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FtsH | | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | | 登録日 | 2006-03-24 | | 公開日 | 2006-06-27 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH
Mol.Cell, 22, 2006
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2DI4
 | | Crystal structure of the FtsH protease domain | | 分子名称: | Cell division protein ftsH homolog, MERCURY (II) ION | | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | | 登録日 | 2006-03-28 | | 公開日 | 2006-06-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH
Mol.Cell, 22, 2006
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5YLT
 | | Crystal structure of SET7/9 in complex with a cyproheptadine derivative | | 分子名称: | 2-(1-methylpiperidin-4-ylidene)tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-6-ol, GLYCEROL, Histone-lysine N-methyltransferase SETD7, ... | | 著者 | Hirano, T, Fujiwara, T, Niwa, H, Hirano, M, Ohira, K, Okazaki, Y, Sato, S, Umehara, T, Maemoto, Y, Ito, A, Yoshida, M, Kagechika, H. | | 登録日 | 2017-10-19 | | 公開日 | 2018-06-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine.
ChemMedChem, 13, 2018
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3CA0
 | | Sambucus nigra agglutinin II (SNA-II), hexagonal crystal form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Agglutinin II, ... | | 著者 | Maveyraud, L, Niwa, H, Guillet, V, Palmer, R.A, Reynolds, C.D, Mourey, L. | | 登録日 | 2008-02-19 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra
Proteins, 75, 2009
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2BJW
 | | PspF AAA domain | | 分子名称: | PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | 著者 | Rappas, M, Schumacher, J, Beuron, F, Niwa, H, Bordes, P, Wigneshweraraj, S, Keetch, C.A, Robinson, C.V, Buck, M, Zhang, X. | | 登録日 | 2005-02-08 | | 公開日 | 2005-03-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Insights Into the Activity of Enhancer-Binding Proteins
Science, 307, 2005
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2BJV
 | | Crystal Structure of PspF(1-275) R168A mutant | | 分子名称: | PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | 著者 | Rappas, M, Schumacher, J, Beuron, F, Niwa, H, Bordes, P, Wigneshweraraj, S, Keetch, C.A, Robinson, C.V, Buck, M, Zhang, X. | | 登録日 | 2005-02-08 | | 公開日 | 2005-03-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Insights Into the Activity of Enhancer-Binding Proteins
Science, 307, 2005
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2C96
 | | Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | | 登録日 | 2005-12-09 | | 公開日 | 2006-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf.
J.Mol.Biol., 357, 2006
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2CXY
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2C98
 | | Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | | 登録日 | 2005-12-09 | | 公開日 | 2006-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf.
J.Mol.Biol., 357, 2006
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2C99
 | | Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | | 登録日 | 2005-12-09 | | 公開日 | 2006-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf.
J.Mol.Biol., 357, 2006
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2C9C
 | | Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | | 登録日 | 2005-12-09 | | 公開日 | 2006-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf.
J.Mol.Biol., 357, 2006
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2EFL
 | | Crystal structure of the EFC domain of formin-binding protein 17 | | 分子名称: | Formin-binding protein 1 | | 著者 | Shimada, A, Niwa, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-02-23 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
Cell(Cambridge,Mass.), 129, 2007
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2EGR
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2EFK
 | | Crystal structure of the EFC domain of Cdc42-interacting protein 4 | | 分子名称: | Cdc42-interacting protein 4 | | 著者 | Shimada, A, Niwa, H, Chen, L, Liu, Z.-J, Wang, B.-C, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-02-23 | | 公開日 | 2007-05-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
Cell(Cambridge,Mass.), 129, 2007
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2EGJ
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5WRL
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide | | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1 | | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | 登録日 | 2016-12-02 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.095 Å) | | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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5WRK
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide | | 分子名称: | AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION | | 著者 | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | 登録日 | 2016-12-02 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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