Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3UN7
DownloadVisualize
BU of 3un7 by Molmil
Crystal structure of PBPA from MYCOBACTERIUM TUBERCULOSIS
分子名称: Penicillin-binding protein A
著者Fedarovich, A, Davies, C.
登録日2011-11-15
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis
J.Mol.Biol., 418, 2012
3UPP
DownloadVisualize
BU of 3upp by Molmil
Structure of penicillin-binding protein A from M. tuberculosis: ceftrixaone acyl-enzyme complex
分子名称: CEFOTAXIME, C3' cleaved, open, ...
著者Davies, C, Fedorovich, A.
登録日2011-11-18
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis
J.Mol.Biol., 418, 2012
3P3E
DownloadVisualize
BU of 3p3e by Molmil
Crystal Structure of the PSEUDOMONAS AERUGINOSA LpxC/LPC-009 complex
分子名称: N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, NITRATE ION, SODIUM ION, ...
著者Lee, C.-J, Zhou, P.
登録日2010-10-04
公開日2011-01-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
3P3G
DownloadVisualize
BU of 3p3g by Molmil
Crystal Structure of the Escherichia coli LpxC/LPC-009 complex
分子名称: 4-ethynyl-N-[(1S,2R)-2-hydroxy-1-(oxocarbamoyl)propyl]benzamide, DIMETHYL SULFOXIDE, N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, ...
著者Lee, C.-J, Zhou, P.
登録日2010-10-04
公開日2011-01-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
3UPN
DownloadVisualize
BU of 3upn by Molmil
Structure of penicillin-binding protein A from M. tuberculosis: imipenem acyl-enzyme complex
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Penicillin-binding protein A
著者Davies, C, Fedorovich, A.
登録日2011-11-18
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis
J.Mol.Biol., 418, 2012
3UPO
DownloadVisualize
BU of 3upo by Molmil
Structure of penicillin-binding protein A from M. tuberculosis: penicillin G acyl-enzyme complex
分子名称: OPEN FORM - PENICILLIN G, Penicillin-binding protein A
著者Davies, C, Fedorovich, A.
登録日2011-11-18
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis
J.Mol.Biol., 418, 2012
3LO7
DownloadVisualize
BU of 3lo7 by Molmil
Crystal structure of PBPA from Mycobacterium tuberculosis
分子名称: Penicillin-binding protein A
著者Fedarovich, A, Davies, C.
登録日2010-02-03
公開日2010-03-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis.
J.Mol.Biol., 398, 2010
2G5D
DownloadVisualize
BU of 2g5d by Molmil
Crystal structure of MltA from Neisseria gonorrhoeae Monoclinic form
分子名称: GNA33
著者Davies, C.
登録日2006-02-22
公開日2006-03-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of the Lytic Transglycosylase MltA from N.gonorrhoeae and E.coli: Insights into Interdomain Movements and Substrate Binding.
J.Mol.Biol., 359, 2006
6VBC
DownloadVisualize
BU of 6vbc by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041
分子名称: Probable peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-12-18
公開日2020-04-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics
J.Biol.Chem., 2020
6VBM
DownloadVisualize
BU of 6vbm by Molmil
Crystal structure of a S310A mutant of PBP2 from Neisseria gonorrhoeae
分子名称: PHOSPHATE ION, Probable peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-12-19
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics
J.Biol.Chem., 2020
6VBD
DownloadVisualize
BU of 6vbd by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 acylated by ceftriaxone
分子名称: CEFOTAXIME, C3' cleaved, open, ...
著者Singh, A, Davies, C.
登録日2019-12-18
公開日2020-04-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics
J.Biol.Chem., 2020
6VBL
DownloadVisualize
BU of 6vbl by Molmil
Crystal structure of the transpeptidase domain of PBP2 from the Neisseria gonorrhoeae cephalosporin decreased susceptibility strain 35/02
分子名称: Probable peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-12-19
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics
J.Biol.Chem., 2020
6P56
DownloadVisualize
BU of 6p56 by Molmil
Crystal structure of the transpeptidase domain of a T498A mutant of PBP2 from Neisseria gonorrhoeae
分子名称: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P52
DownloadVisualize
BU of 6p52 by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae with a bound phosphate at the active site
分子名称: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P53
DownloadVisualize
BU of 6p53 by Molmil
Crystal structure of the transpeptidase domain of PBP2 from Neisseria gonorrhoeae in apo form
分子名称: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P54
DownloadVisualize
BU of 6p54 by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae acylated by ceftriaxone
分子名称: CEFOTAXIME, C3' cleaved, open, ...
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P55
DownloadVisualize
BU of 6p55 by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae acylated by cefixime
分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, cefixime, ...
著者Singh, A, Davies, C.
登録日2019-05-29
公開日2019-08-07
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
8E4A
DownloadVisualize
BU of 8e4a by Molmil
Pseudomonas LpxC in complex with LPC-233
分子名称: 4-(4-cyclopropylbuta-1,3-diyn-1-yl)-N-[(2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]benzamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION
著者Najeeb, J, Zhou, P.
登録日2022-08-17
公開日2023-08-23
実験手法X-RAY DIFFRACTION (2.034 Å)
主引用文献Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens.
Sci Transl Med, 15, 2023
<12

 

219869

件を2024-05-15に公開中

PDB statisticsPDBj update infoContact PDBjnumon