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8GNK
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BU of 8gnk by Molmil
CryoEM structure of cytosol-facing, substrate-bound ratGAT1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ...
Authors:Nayak, S.R, Joseph, D, Penmatsa, A.
Deposit date:2022-08-24
Release date:2023-05-31
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism.
Nat.Struct.Mol.Biol., 30, 2023
7WLW
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BU of 7wlw by Molmil
X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with SKF89976a
Descriptor: (3S)-1-(4,4-diphenylbut-3-enyl)piperidine-3-carboxylic acid, Antibody Fragment heavy chain, Antibody fragment light chain, ...
Authors:Penmatsa, A, Joseph, D.
Deposit date:2022-01-13
Release date:2022-06-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter.
Embo J., 41, 2022
7WGD
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BU of 7wgd by Molmil
X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in substrate-free form.
Descriptor: Antibody fragment (9D5) Light Chain, Antibody fragment (9D5) heavy chain, CHLORIDE ION, ...
Authors:Joseph, D, Penmatsa, A.
Deposit date:2021-12-28
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter.
Embo J., 41, 2022
7WGT
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BU of 7wgt by Molmil
X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with NO711.
Descriptor: 1-(2-{[(diphenylmethylidene)amino]oxy}ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid, Antibody fragment (9D5) heavy chain, Antibody fragment (9D5) light chain, ...
Authors:Joseph, D, Penmatsa, A.
Deposit date:2021-12-28
Release date:2022-06-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter.
Embo J., 41, 2022

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PDB entries from 2024-10-30

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