5M5L
| Pseudo-atomic model of microtubule-bound S. pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-21 | Release date: | 2016-11-30 | Last modified: | 2018-12-05 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5I
| Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus conformation allows formation of a cover neck bundle. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-21 | Release date: | 2016-11-30 | Last modified: | 2018-06-20 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5O
| Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-22 | Release date: | 2016-11-30 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5M
| Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-21 | Release date: | 2016-11-30 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5ND7
| Microtubule-bound MKLP2 motor domain in the presence of AMPPNP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ... | Authors: | Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | Deposit date: | 2017-03-07 | Release date: | 2017-10-04 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
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5N5N
| Cryo-EM structure of tsA201 cell alpha1B and betaI and betaIVb microtubules | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Vemu, A, Atherton, J, Spector, J.O, Moores, C.A, Roll-Mecak, A. | Deposit date: | 2017-02-14 | Release date: | 2017-11-01 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Tubulin isoform composition tunes microtubule dynamics. Mol. Biol. Cell, 28, 2017
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5ND4
| Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | Deposit date: | 2017-03-07 | Release date: | 2017-10-04 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
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5ND2
| Microtubule-bound MKLP2 motor domain in the presence of ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | Deposit date: | 2017-03-07 | Release date: | 2017-10-04 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
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5ND3
| Microtubule-bound MKLP2 motor domain in the with no nucleotide | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ... | Authors: | Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | Deposit date: | 2017-03-07 | Release date: | 2017-10-04 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
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2VE7
| Crystal structure of a bonsai version of the human Ndc80 complex | Descriptor: | GLYCEROL, KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25, ... | Authors: | Ciferri, C, Pasqualato, S, Dos Reis, G, Screpanti, E, Maiolica, A, Polka, J, De Luca, J.G, De Wulf, P, Salek, M, Rappsilber, J, Moores, C.A, Salmon, E.D, Musacchio, A. | Deposit date: | 2007-10-17 | Release date: | 2008-05-13 | Last modified: | 2022-05-04 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex Cell(Cambridge,Mass.), 133, 2008
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2WBE
| Kinesin-5-Tubulin Complex with AMPPNP | Descriptor: | BIPOLAR KINESIN KRP-130, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Bodey, A.J, Kikkawa, M, Moores, C.A. | Deposit date: | 2009-02-26 | Release date: | 2009-03-24 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | 9-Angstrom Structure of a Microtubule-Bound Mitotic Motor. J.Mol.Biol., 388, 2009
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2XRP
| Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the 8-Angstrom Cryo-EM Map of Doublecortin- Stabilised Microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ... | Authors: | Fourniol, F.J, Sindelar, C.V, Amigues, B, Clare, D.K, Thomas, G, Perderiset, M, Francis, F, Houdusse, A, Moores, C.A. | Deposit date: | 2010-09-18 | Release date: | 2010-11-24 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Template-Free 13-Protofilament Microtubule-Map Assembly Visualized at 8 A Resolution. J.Cell Biol., 191, 2010
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3LRE
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7NB8
| Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule. | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-5, MAGNESIUM ION, ... | Authors: | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | Deposit date: | 2021-01-25 | Release date: | 2021-10-13 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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7NBA
| Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule. | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin motor domain-containing protein,Kinesin motor domain-containing protein, MAGNESIUM ION, ... | Authors: | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | Deposit date: | 2021-01-25 | Release date: | 2021-10-13 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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5OAM
| Molecular basis of human kinesin-8 function and inhibition | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF18A, ... | Authors: | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | Deposit date: | 2017-06-23 | Release date: | 2017-10-25 | Last modified: | 2019-08-21 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structural basis of human kinesin-8 function and inhibition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OCU
| Molecular basis of human kinesin-8 function and inhibition | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF18A, ... | Authors: | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | Deposit date: | 2017-07-03 | Release date: | 2017-10-25 | Last modified: | 2019-08-21 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Structural basis of human kinesin-8 function and inhibition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OGC
| Molecular basis of human kinesin-8 function and inhibition | Descriptor: | 4-chloranyl-2-nitro-1-(phenylsulfonyl)benzene, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | Deposit date: | 2017-07-12 | Release date: | 2017-10-25 | Last modified: | 2019-08-21 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural basis of human kinesin-8 function and inhibition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1QAG
| Actin binding region of the dystrophin homologue utrophin | Descriptor: | UTROPHIN ACTIN BINDING REGION | Authors: | Keep, N.H, Winder, S.J, Moores, C.A, Walke, S, Norwood, F.L.M, Kendrick-Jones, J. | Deposit date: | 1999-03-05 | Release date: | 2000-01-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer Structure Fold.Des., 7, 1999
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5MM7
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5MM4
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4UXS
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXR
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UY0
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXO
| Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2018-04-04 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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