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3WMH
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BU of 3wmh by Molmil
Human PPAR gamma ligand binding domain in complex with a gammma selective synthetic partial agonist MEKT75
分子名称: N-(phenylsulfonyl)-4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)benzamide, Peroxisome proliferator-activated receptor gamma
著者Oyama, T, Ohashi, M, Miyachi, H, Kusunoki, M.
登録日2013-11-19
公開日2014-11-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human PPRR gamma ligand binding domain in complex with a gammma selective synthetic partial agonist MEKT75
TO BE PUBLISHED
3VJH
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BU of 3vjh by Molmil
Human PPAR GAMMA ligand binding domain in complex with JKPL35
分子名称: (2S)-2-[4-methoxy-3-({[4-(trifluoromethyl)benzoyl]amino}methyl)benzyl]pentanoic acid, Peroxisome proliferator-activated receptor gamma
著者Tomioka, D, Kuwabara, N, Hashimoto, H, Sato, M, Shimizu, T.
登録日2011-10-20
公開日2012-08-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype.
J.Med.Chem., 55, 2012
3VJI
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BU of 3vji by Molmil
Human PPAR gamma ligand binding domain in complex with JKPL53
分子名称: (2S)-2-{4-butoxy-3-[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]benzoyl}amino)methyl]benzyl}butanoic acid, Peroxisome proliferator-activated receptor gamma
著者Tomioka, D, Kuwabara, N, Hashimoto, H, Sato, M, Shimizu, T.
登録日2011-10-20
公開日2012-08-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype.
J.Med.Chem., 55, 2012
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件を2024-05-22に公開中

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