7TAL
| LOV2-DARPIN fusion : D4_deltaDARP | 分子名称: | D4_deltaDARP LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION | 著者 | Mittl, P. | 登録日 | 2021-12-21 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | LOV2-DARPIN fusion : D4_deltaDARP To Be Published
|
|
1GER
| |
4V3Q
| Designed armadillo repeat protein with 4 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | 分子名称: | CALCIUM ION, GLYCEROL, YIII_M4_AII | 著者 | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | 登録日 | 2014-10-20 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects. Acta Crystallogr D Struct Biol, 72, 2016
|
|
2AXI
| HDM2 in complex with a beta-hairpin | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION, Ubiquitin-protein ligase E3 Mdm2, ... | 著者 | Mittl, P.R.E, Fasan, R, Robinson, J, Gruetter, M.G. | 登録日 | 2005-09-05 | 公開日 | 2006-03-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure-Activity Studies in a Family of beta-Hairpin Protein Epitope Mimetic Inhibitors of the p53-HDM2 Protein-Protein Interaction. Chembiochem, 7, 2006
|
|
1BX7
| HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.2 ANGSTROMS | 分子名称: | HIRUSTASIN, SULFATE ION | 著者 | Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E. | 登録日 | 1998-10-14 | 公開日 | 1999-04-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors. Structure Fold.Des., 7, 1999
|
|
1BX8
| HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.4 ANGSTROMS | 分子名称: | HIRUSTASIN, SULFATE ION | 著者 | Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E. | 登録日 | 1998-10-14 | 公開日 | 1999-04-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors. Structure Fold.Des., 7, 1999
|
|
5AAO
| Crystal structure of fluorogen-activating designed ankyrin repeat protein (DARPin) dimer in complex with malachite green | 分子名称: | 4-[[4-(dimethylamino)cyclohexa-2,5-dien-1-ylidene]-(4-methoxyphenyl)methyl]-N,N-dimethyl-aniline, FAD3210 | 著者 | Batyuk, A, Schuetz, M, Kummer, L, Wu, Y, Mittl, P, Plueckthun, A. | 登録日 | 2015-07-27 | 公開日 | 2016-02-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools. J. Mol. Biol., 428, 2016
|
|
5AN7
| Structure of the engineered retro-aldolase RA95.5-8F with a bound 1,3-diketone inhibitor | 分子名称: | (2E)-1-(6-methoxynaphthalen-2-yl)but-2-en-1-one, PHOSPHATE ION, RA95.5-8F | 著者 | Obexer, R, Mittl, P.R.E, Hilvert, D. | 登録日 | 2015-09-04 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase. Nat Chem, 9, 2017
|
|
5AOU
| Structure of the engineered retro-aldolase RA95.5-8F apo | 分子名称: | 1,2-ETHANEDIOL, INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE, PHOSPHATE ION | 著者 | Obexer, R, Mittl, P, Hilvert, D. | 登録日 | 2015-09-11 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase. Nat Chem, 9, 2017
|
|
4PLR
| Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure. | 分子名称: | Arm00008, CALCIUM ION | 著者 | Reichen, C, Madhurantakam, C, Plueckthun, A, Mittl, P. | 登録日 | 2014-05-19 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of designed armadillo repeat proteins: Implications of construct design and crystallization conditions on overall structure. Protein Sci., 23, 2014
|
|
1KLX
| |
1KKC
| Crystal structure of Aspergillus fumigatus MnSOD | 分子名称: | MANGANESE (II) ION, Manganese Superoxide Dismutase | 著者 | Fluckiger, S, Mittl, P.R.E, Scapozza, L, Fijten, H, Folkers, G, Grutter, M.G, Blaser, K, Crameri, R. | 登録日 | 2001-12-07 | 公開日 | 2001-12-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. J.Immunol., 168, 2002
|
|
4ATZ
| |
1FG2
| CRYSTAL STRUCTURE OF THE LCMV PEPTIDIC EPITOPE GP33 IN COMPLEX WITH THE MURINE CLASS I MHC MOLECULE H-2DB | 分子名称: | BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... | 著者 | Tissot, A.C, Ciatto, C, Mittl, P.R.E, Gruetter, M.G, Plueckthun, A. | 登録日 | 2000-07-27 | 公開日 | 2000-10-04 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.754 Å) | 主引用文献 | Viral escape at the molecular level explained by quantitative T-cell receptor/peptide/MHC interactions and the crystal structure of a peptide/MHC complex. J.Mol.Biol., 302, 2000
|
|
3N2W
| Crystal structure of the N-terminal beta-aminopeptidase BapA from Sphingosinicella xenopeptidilytica | 分子名称: | Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION | 著者 | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | 登録日 | 2010-05-19 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family. Structure, 20, 2012
|
|
3N33
| Crystal structure of the N-terminal beta-aminopeptidase BapA in complex with pefabloc SC (AEBSF) | 分子名称: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-peptidyl aminopeptidase, ... | 著者 | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | 登録日 | 2010-05-19 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family. Structure, 20, 2012
|
|
3N5I
| Crystal structure of the precursor (S250A mutant) of the N-terminal beta-aminopeptidase BapA | 分子名称: | Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION | 著者 | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | 登録日 | 2010-05-25 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family. Structure, 20, 2012
|
|
1QDU
| |
4DB6
| Designed Armadillo repeat protein (YIIIM3AII) | 分子名称: | Armadillo repeat protein | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | 登録日 | 2012-01-13 | 公開日 | 2012-05-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
|
|
4DB8
| Designed Armadillo-repeat Protein | 分子名称: | Armadillo-repeat Protein, MAGNESIUM ION | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | 登録日 | 2012-01-13 | 公開日 | 2012-05-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
|
|
4DBA
| Designed Armadillo repeat protein (YIIM3AII) | 分子名称: | Designed Armadillo repeat protein, YIIM3AII, GLYCEROL | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | 登録日 | 2012-01-13 | 公開日 | 2012-05-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
|
|
4DB9
| Designed Armadillo repeat protein (YIIIM3AIII) | 分子名称: | Armadillo repeat protein, YIIIM3AIII | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | 登録日 | 2012-01-13 | 公開日 | 2012-05-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
|
|
5L86
| engineered ascorbate peroxidise | 分子名称: | Ascorbate peroxidase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Hayashi, T, Mittl, P, Hilvert, D. | 登録日 | 2016-06-07 | 公開日 | 2017-03-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Chemically Programmed Proximal Ligand Enhances the Catalytic Properties of a Heme Enzyme. J. Am. Chem. Soc., 138, 2016
|
|
5LE2
| Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_15_D12_15_D12 | 分子名称: | ACETATE ION, DDD_D12_15_D12_15_D12, THIOCYANATE ION | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | 登録日 | 2016-06-29 | 公開日 | 2017-08-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7, 2017
|
|
5LEC
| Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_12_D12_12_D12 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DDD_D12_12_D12_12_D12 | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | 登録日 | 2016-06-29 | 公開日 | 2017-08-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7, 2017
|
|