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7NYC
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BU of 7nyc by Molmil
cryoEM structure of 3C9-sMAC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Menny, A, Couves, E.C, Bubeck, D.
登録日2021-03-22
公開日2021-10-06
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
7NYD
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BU of 7nyd by Molmil
cryoEM structure of 2C9-sMAC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Menny, A, Couves, E.C, Bubeck, D.
登録日2021-03-22
公開日2021-10-06
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
6H03
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BU of 6h03 by Molmil
OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
著者Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
登録日2018-07-06
公開日2018-12-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
6H04
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BU of 6h04 by Molmil
Closed conformation of the Membrane Attack Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
著者Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
登録日2018-07-06
公開日2018-12-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
5IUX
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BU of 5iux by Molmil
GLIC-V135C bimane labelled X-ray structure
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,3,5,6-tetramethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, ACETATE ION, ...
著者Fourati, Z, Menny, A, Delarue, M.
登録日2016-03-18
公開日2017-03-29
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a pre-active conformation of a pentameric channel receptor.
Elife, 6, 2017
4NPP
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BU of 4npp by Molmil
The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms
分子名称: NICKEL (II) ION, Proton-gated ion channel
著者Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M.
登録日2013-11-22
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NPQ
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BU of 4npq by Molmil
The resting-state conformation of the GLIC ligand-gated ion channel
分子名称: Proton-gated ion channel
著者Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M.
登録日2013-11-22
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.35 Å)
主引用文献Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.
Proc.Natl.Acad.Sci.USA, 111, 2014
6HZ3
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BU of 6hz3 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243G
分子名称: CHLORIDE ION, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HZ1
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BU of 6hz1 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYW
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BU of 6hyw by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y119F
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HZ0
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BU of 6hz0 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248A
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HZW
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BU of 6hzw by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL 2.22 resolution
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-24
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HY5
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BU of 6hy5 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-19
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYV
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BU of 6hyv by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y119A
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYR
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BU of 6hyr by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C+MMTS
分子名称: DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYX
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BU of 6hyx by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y197F-P250C
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYA
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BU of 6hya by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-19
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYZ
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BU of 6hyz by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248C
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6I08
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BU of 6i08 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C-I201W
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-25
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HY9
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BU of 6hy9 by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193M
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel
著者Hu, H.D, Delarue, M.
登録日2018-10-19
公開日2018-12-19
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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