3C9R
 
 | | AaThiL complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Thiamine monophosphate kinase | | 著者 | McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-02-18 | | 公開日 | 2008-03-18 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
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3GMC
 | | Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase with substrate bound | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxy-6-methylpyridine-3-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-03-13 | | 公開日 | 2009-04-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
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3GMB
 | | Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-03-13 | | 公開日 | 2009-04-14 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
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3KXP
 | | Crystal Structure of E-2-(Acetamidomethylene)succinate Hydrolase | | 分子名称: | Alpha-(N-acetylaminomethylene)succinic acid hydrolase, CHLORIDE ION | | 著者 | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-12-03 | | 公開日 | 2010-02-09 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structure determination and characterization of the vitamin B(6) degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase.
Biochemistry, 49, 2010
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3O15
 | | Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase Complexed with a Carboxylated Thiazole Phosphate | | 分子名称: | 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, PYROPHOSPHATE 2-, ... | | 著者 | McCulloch, K.M, Hanes, J.W, Abdelwahed, S, Mahanta, N, Hazra, A, Ishida, K, Begley, T.P, Ealick, S.E. | | 登録日 | 2010-07-20 | | 公開日 | 2011-07-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure and Kinetic Characterization of Bacillus subtilis
Thiamin Phosphate Synthase with a Carboxylated Thiazole Phosphate
to be published
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3O16
 | | Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase K159A | | 分子名称: | Thiamine-phosphate pyrophosphorylase | | 著者 | McCulloch, K.M, Hanes, J.W, Abdelwahed, S, Mahanta, N, Hazra, A, Ishida, K, Begley, T.P, Ealick, S.E. | | 登録日 | 2010-07-20 | | 公開日 | 2011-07-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure and Kinetic Characterization of Bacillus subtilis Thiamin
Phosphate Synthase with a Carboxylated Thiazole Phosphate
to be published
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3O63
 | | Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis | | 分子名称: | PHOSPHATE ION, Probable thiamine-phosphate pyrophosphorylase | | 著者 | McCulloch, K.M, Ramamoorthy, D, Ishida, K, Guida, W.C, Begley, T.P, Ealick, S.E. | | 登録日 | 2010-07-28 | | 公開日 | 2011-07-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure and Identification of Potential Inhibitor Compounds for Mycobacterium tuberculosis Thiamin Phosphate Synthase
to be published
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3C9S
 | | AaThiL complexed with AMPPCP | | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Thiamine monophosphate kinase | | 著者 | McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-02-18 | | 公開日 | 2008-03-18 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
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3C9T
 | | AaThiL complexed with AMPPCP and TMP | | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, THIAMIN PHOSPHATE, ... | | 著者 | McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-02-18 | | 公開日 | 2008-03-18 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
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3C9U
 | | AaThiL complexed with ADP and TPP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | | 著者 | McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-02-18 | | 公開日 | 2008-03-18 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
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4XAC
 | | Crystal Structure of EvdO2 from Micromonospora carbonacea var. aurantiaca complexed with 2-oxoglutarate | | 分子名称: | 2-OXOGLUTARIC ACID, EvdO2, IMIDAZOLE, ... | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2014-12-13 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XCA
 | | Crystal Structure of HygX from Streptomyces hygroscopicus with nickel and 2-oxoglutarate bound | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-OXOGLUTARIC ACID, CESIUM ION, ... | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2014-12-17 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XAB
 | | Crystal Structure of EvdO2 from Micromonospora carbonacea var. aurantiaca | | 分子名称: | EvdO2, IMIDAZOLE, NICKEL (II) ION | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2014-12-13 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XAA
 | | Crystal Structure of AviO1 from Streptomyces viridochromogenes Tue57 | | 分子名称: | NICKEL (II) ION, Putative oxygenase | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2014-12-13 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XCB
 | | Crystal Structure of HygX from Streptomyces hygroscopicus with nickel, 2-oxoglutarate, and hygromycin B bound | | 分子名称: | 2-OXOGLUTARIC ACID, HYGROMYCIN B VARIANT, NICKEL (II) ION, ... | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2014-12-17 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XBZ
 | | Crystal Structure of EvdO1 from Micromonospora carbonacea var. aurantiaca | | 分子名称: | EvdO1, GLYCEROL, NICKEL (II) ION | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2014-12-17 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XC9
 | | Crystal Structure of apo HygX from Streptomyces hygroscopicus | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, oxidase/hydroxylase | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2014-12-17 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZPI
 | | Crystal Structure of HygX from Streptomyces hygroscopicus with iron bound | | 分子名称: | FE (II) ION, Putative oxidase/hydroxylase, SUCCINIC ACID | | 著者 | McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2015-05-07 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | | 主引用文献 | Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6B3I
 | | Annexin A13a | | 分子名称: | 1,2-ETHANEDIOL, Annexin | | 著者 | McCulloch, K.M, Iverson, T.M. | | 登録日 | 2017-09-21 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An alternative N-terminal fold of the intestine-specific annexin A13a induces dimerization and regulates membrane-binding.
J. Biol. Chem., 294, 2019
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6EC3
 | | Crystal Structure of EvdMO1 | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Methyltransferase domain-containing protein, NICKEL (II) ION | | 著者 | McCulloch, K.M, Iverson, T.M, Starbird, C.A, Perry, N.A, Chen, Q, Berndt, S, Yamakawa, I, Loukachevitch, L.V. | | 登録日 | 2018-08-07 | | 公開日 | 2018-12-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Biochemistry, 57, 2018
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5T38
 | | Crystal Structure of the N-terminal domain of EvdMO1 with SAH bound | | 分子名称: | EvdMO1, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | McCulloch, K.M, Berndt, S, Yamakawa, I, Chen, Q, Loukachevitch, L.V, Starbird, C, Perry, N.A, Iverson, T.M. | | 登録日 | 2016-08-25 | | 公開日 | 2017-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.1502 Å) | | 主引用文献 | The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Biochemistry, 57, 2018
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5T39
 | | Crystal Structure of the N-terminal domain of EvdMO1 in the presence of SAH and D-fucose | | 分子名称: | EvdMO1, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | McCulloch, K.M, Starbird, C.A, Chen, Q, Perry, N.A, Berndt, S, Yamakawa, I, Loukachevitch, L.V, Iverson, T.M. | | 登録日 | 2016-08-25 | | 公開日 | 2017-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.1004 Å) | | 主引用文献 | The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Biochemistry, 57, 2018
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2Z7B
 | | Crystal Structure of Mesorhizobium loti 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase | | 分子名称: | MANGANESE (II) ION, Mlr6791 protein | | 著者 | McCulloch, K.M, Mukherjee, T, Ealick, S.E, Begley, T.P. | | 登録日 | 2007-08-17 | | 公開日 | 2007-11-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Gene Identification and Structural Characterization of the Pyridoxal 5'-Phosphate Degradative Protein 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate Decarboxylase from Mesorhizobium loti MAFF303099
Biochemistry, 46, 2007
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5EQ4
 | | Crystal structure of the SrpA adhesin R347E mutant from Streptococcus sanguinis | | 分子名称: | ACETATE ION, CALCIUM ION, Platelet-binding glycoprotein | | 著者 | Loukachevitch, L.V, McCulloch, K.M, Vann, K.R, Wawrzak, Z, Anderson, S, Iverson, T.M. | | 登録日 | 2015-11-12 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.
J.Biol.Chem., 291, 2016
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5EQ2
 | | Crystal Structure of the SrpA Adhesin from Streptococcus sanguinis | | 分子名称: | ACETATE ION, CALCIUM ION, Platelet-binding glycoprotein | | 著者 | Loukachevitch, L.V, McCulloch, K.M, Vann, K.R, Wawrzak, Z, Anderson, S, Iverson, T.M. | | 登録日 | 2015-11-12 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.
J.Biol.Chem., 291, 2016
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