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3O63

Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis

Summary for 3O63
Entry DOI10.2210/pdb3o63/pdb
DescriptorProbable thiamine-phosphate pyrophosphorylase, PHOSPHATE ION (3 entities in total)
Functional Keywordsthiamin biosynthesis, tim barrel, transferase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains2
Total formula weight51615.70
Authors
McCulloch, K.M.,Ramamoorthy, D.,Ishida, K.,Guida, W.C.,Begley, T.P.,Ealick, S.E. (deposition date: 2010-07-28, release date: 2011-07-27, Last modification date: 2024-02-21)
Primary citationMcCulloch, K.M.,Ramamoorthy, D.,Ishida, K.,Guida, W.C.,Begley, T.P.,Ealick, S.E.
Crystal Structure and Identification of Potential Inhibitor Compounds for Mycobacterium tuberculosis Thiamin Phosphate Synthase
to be published,
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

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