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7N1D
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BU of 7n1d by Molmil
SARS-CoV-2 YLQ peptide-specific TCR pYLQ7
Descriptor: pYLQ7 T cell receptor alpha chain, pYLQ7 T cell receptor beta chain
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
3D34
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BU of 3d34 by Molmil
Structure of the F-spondin domain of mindin
Descriptor: CALCIUM ION, NICKEL (II) ION, Spondin-2
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2008-05-09
Release date:2009-02-17
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule.
Embo J., 28, 2009
7REV
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BU of 7rev by Molmil
Co-crystal structure of Chaetomium glucosidase with compound 3
Descriptor: (2R,3R,4R,5S)-1-[(4-{[4-(furan-2-yl)-2-methylanilino]methyl}phenyl)methyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-07-13
Release date:2022-08-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity.
J.Med.Chem., 66, 2023
7RM4
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BU of 7rm4 by Molmil
Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2
Descriptor: 6-11 T cell receptor alpha chain, 6-11 T cell receptor beta chain, Beta-2-microglobulin, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-07-26
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:T cell receptors employ diverse strategies to target a p53 cancer neoantigen.
J.Biol.Chem., 298, 2022
7R6J
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BU of 7r6j by Molmil
Co-crystal structure of Chaetomium glucosidase with compound 1
Descriptor: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[(3-{[3-methyl-5-(pyrimidin-2-yl)anilino]methyl}phenyl)methyl]piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-06-22
Release date:2022-07-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.905 Å)
Cite:Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity.
J.Med.Chem., 66, 2023
3FF7
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BU of 3ff7 by Molmil
Structure of NK cell receptor KLRG1 bound to E-cadherin
Descriptor: ACETIC ACID, Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2008-12-02
Release date:2009-07-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Immunity, 31, 2009
3FF9
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BU of 3ff9 by Molmil
Structure of NK cell receptor KLRG1
Descriptor: Killer cell lectin-like receptor subfamily G member 1
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2008-12-02
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Immunity, 31, 2009
3FF8
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BU of 3ff8 by Molmil
Structure of NK cell receptor KLRG1 bound to E-cadherin
Descriptor: CALCIUM ION, Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2008-12-02
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Immunity, 31, 2009
3G39
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BU of 3g39 by Molmil
Structure of a lamprey variable lymphocyte receptor
Descriptor: Variable lymphocyte receptor VLRB.2D
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3A
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BU of 3g3a by Molmil
Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen
Descriptor: Lysozyme C, Variable lymphocyte receptor VLRB.2D
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3B
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BU of 3g3b by Molmil
Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen
Descriptor: Lysozyme C, variable lymphocyte receptor VLRB.2D
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
1FM5
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BU of 1fm5 by Molmil
CRYSTAL STRUCTURE OF HUMAN CD69
Descriptor: EARLY ACTIVATION ANTIGEN CD69
Authors:Natarajan, K, Sawicki, M.W, Margulies, D.H, Mariuzza, R.A.
Deposit date:2000-08-16
Release date:2000-12-18
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.
Biochemistry, 39, 2000
1G7H
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BU of 1g7h by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7J
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BU of 1g7j by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7M
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BU of 1g7m by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7L
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BU of 1g7l by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7I
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BU of 1g7i by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C, PHOSPHATE ION
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1DDH
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BU of 1ddh by Molmil
MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN IMMUNODOMINANT PEPTIDE P18-I10 FROM THE HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
Descriptor: BETA-2 MICROGLOBULIN, HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120, MHC CLASS I H-2DD HEAVY CHAIN
Authors:Li, H, Margulies, D.H, Mariuzza, R.A.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120.
J.Mol.Biol., 283, 1998
1P1Z
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BU of 1p1z by Molmil
X-RAY CRYSTAL STRUCTURE OF THE LECTIN-LIKE NATURAL KILLER CELL RECEPTOR LY-49C BOUND TO ITS MHC CLASS I LIGAND H-2Kb
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
Authors:Dimasi, N, Natarajan, K, Rangjin, G, Dam, J, Margulies, D.H, Mariuzza, R.A.
Deposit date:2003-04-14
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4, 2003
1PYW
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BU of 1pyw by Molmil
Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Descriptor: 9-residue influenza virus hemagglutinin related peptide FVKQNA(MAA)AL, Enterotoxin type C-3, HLA class II histocompatibility antigen, ...
Authors:Zavala-Ruiz, Z, Sundberg, E.J, Stone, J.D, DeOliveira, D.B, Chan, I.C, Svendsen, J, Mariuzza, R.A, Stern, L.J.
Deposit date:2003-07-09
Release date:2003-12-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1
J.Biol.Chem., 278, 2003
1R1Q
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BU of 1r1q by Molmil
Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads
Descriptor: GRB2-related adaptor protein 2, LAT pY191 peptide, SULFATE ION
Authors:Cho, S, Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
1R1S
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BU of 1r1s by Molmil
Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads
Descriptor: GRB2-related adaptor protein 2, LAT pY226 peptide, SULFATE ION
Authors:Cho, S, Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
1R1P
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BU of 1r1p by Molmil
Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads
Descriptor: GRB2-related adaptor protein 2, LAT pY171 peptide, SULFATE ION
Authors:Cho, S, Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
1SK3
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BU of 1sk3 by Molmil
Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
Descriptor: NICKEL (II) ION, Peptidoglycan recognition protein I-alpha, SULFATE ION
Authors:Guan, R, Malchiodi, E.L, Qian, W, Schuck, P, Mariuzza, R.A.
Deposit date:2004-03-04
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
J.Biol.Chem., 279, 2004
1SBB
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BU of 1sbb by Molmil
T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SEB
Descriptor: PROTEIN (14.3.D T CELL ANTIGEN RECEPTOR), PROTEIN (STAPHYLOCOCCAL ENTEROTOXIN B)
Authors:Li, H, Mariuzza, R.A.
Deposit date:1999-02-22
Release date:1999-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B.
Immunity, 9, 1998

219869

數據於2024-05-15公開中

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