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4E41
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BU of 4e41 by Molmil
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A.
Deposit date:2012-03-11
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
5TEZ
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BU of 5tez by Molmil
TCR F50 recgonizing M1-HLA-A2
Descriptor: Beta-2-microglobulin, GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU, HLA class I histocompatibility antigen, ...
Authors:Yang, X, Mariuzza, R.A.
Deposit date:2016-09-23
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope.
J. Biol. Chem., 292, 2017
7N1F
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BU of 7n1f by Molmil
SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 binds to YLQ-HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1A
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BU of 7n1a by Molmil
SARS-CoV-2 YLQ peptide binds to HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.065 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1B
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BU of 7n1b by Molmil
SARS-CoV-2 RLQ peptide binds to HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1E
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BU of 7n1e by Molmil
SARS-CoV-2 RLQ peptide-specific TCR pRLQ3 binds to RLQ-HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1D
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BU of 7n1d by Molmil
SARS-CoV-2 YLQ peptide-specific TCR pYLQ7
Descriptor: pYLQ7 T cell receptor alpha chain, pYLQ7 T cell receptor beta chain
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1C
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BU of 7n1c by Molmil
SARS-CoV-2 RLQ peptide-specific TCR pRLQ3
Descriptor: pRLQ3 T cell receptor alpha chain, pRLQ3 T cell receptor beta chain
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
4K79
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BU of 4k79 by Molmil
Recognition of the Thomsen-Friedenreich Antigen by a Lamprey Variable Lymphocyte Receptor
Descriptor: Variable lymphocyte receptor, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
Authors:Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A.
Deposit date:2013-04-16
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
4K5U
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BU of 4k5u by Molmil
Recognition of the BG-H Antigen by a Lamprey Variable Lymphocyte Receptor
Descriptor: Variable lymphocyte receptor, beta-D-galactopyranose
Authors:Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A.
Deposit date:2013-04-15
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
1JCK
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BU of 1jck by Molmil
T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SEC3 SUPERANTIGEN
Descriptor: 14.3.D T CELL ANTIGEN RECEPTOR, STAPHYLOCOCCAL ENTEROTOXIN C3
Authors:Fields, B.A, Mariuzza, R.A.
Deposit date:1996-10-22
Release date:1997-11-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a T-cell receptor beta-chain complexed with a superantigen.
Nature, 384, 1996
1BEC
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BU of 1bec by Molmil
BETA CHAIN OF A T CELL ANTIGEN RECEPTOR
Descriptor: 14.3.D T CELL ANTIGEN RECEPTOR
Authors:Bentley, G.A, Boulot, G, Karjalainen, K, Mariuzza, R.A.
Deposit date:1995-02-28
Release date:1995-10-25
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the beta chain of a T cell antigen receptor.
Science, 267, 1995
3C8J
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BU of 3c8j by Molmil
The crystal structure of natural killer cell receptor Ly49C
Descriptor: Natural killer cell receptor Ly49C
Authors:Deng, L, Mariuzza, R.A.
Deposit date:2008-02-12
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008
3L6F
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BU of 3l6f by Molmil
Structure of MHC class II molecule HLA-DR1 complexed with phosphopeptide MART-1
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2009-12-23
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Presentation of Tumor-Associated MHC Class II-Restricted Phosphopeptides to CD4(+) T Cells.
J.Mol.Biol., 399, 2010
3M19
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BU of 3m19 by Molmil
Crystal structure of variable lymphocyte receptor VLRA.R5.1
Descriptor: Variable lymphocyte receptor A diversity region
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M18
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BU of 3m18 by Molmil
Crystal structure of variable lymphocyte receptor VLRA.R2.1 in complex with hen egg lysozyme
Descriptor: Lysozyme C, PHOSPHATE ION, Variable lymphocyte receptor A diversity region
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MC0
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BU of 3mc0 by Molmil
Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain
Descriptor: ACETATE ION, Enterotoxin SEG, variable beta 8.2 mouse T cell receptor
Authors:Fernandez, M.M, Cho, S, Robinson, H, Mariuzza, R.A, Malchiodi, E.L.
Deposit date:2010-03-26
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
J.Biol.Chem., 286, 2011
3O6F
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BU of 3o6f by Molmil
Crystal structure of a human autoimmune TCR MS2-3C8 bound to MHC class II self-ligand MBP/HLA-DR4
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
Authors:Yin, Y, Li, Y, Martin, R, Mariuzza, R.A.
Deposit date:2010-07-29
Release date:2011-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection.
Embo J., 30, 2011
1KIP
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BU of 1kip by Molmil
FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: LYSOZYME, MONOCLONAL ANTIBODY D1.3
Authors:Fields, B.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIR
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BU of 1kir by Molmil
FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: LYSOZYME, MONOCLONAL ANTIBODY D1.3
Authors:Fields, B.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIQ
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BU of 1kiq by Molmil
FV MUTANT Y(B 101)F (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: LYSOZYME, MONOCLONAL ANTIBODY D1.3
Authors:Fields, B.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1QO3
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BU of 1qo3 by Molmil
Complex between NK cell receptor Ly49A and its MHC class I ligand H-2Dd
Descriptor: 1,2-ETHANEDIOL, BETA-2-MICROGLOBULIN, HIV ENVELOPE GLYCOPROTEIN 120 PEPTIDE, ...
Authors:Tormo, J, Mariuzza, R.A.
Deposit date:1999-11-01
Release date:2000-01-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Lectin-Like Natural Killer Cell Receptor Bound to its Mhc Class I Ligand
Nature, 402, 1999
1DVF
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BU of 1dvf by Molmil
IDIOTOPIC ANTIBODY D1.3 FV FRAGMENT-ANTIIDIOTOPIC ANTIBODY E5.2 FV FRAGMENT COMPLEX
Descriptor: FV D1.3, FV E5.2, ZINC ION
Authors:Braden, B.C, Fields, B.A, Ysern, X, Dall'Acqua, W, Goldbaum, F.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-04-13
Release date:1996-08-17
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution.
J.Mol.Biol., 264, 1996
1TVD
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BU of 1tvd by Molmil
VARIABLE DOMAIN OF T CELL RECEPTOR DELTA CHAIN
Descriptor: T CELL RECEPTOR
Authors:Li, H.M, Lebedeva, M.I, Llera, A.S, Fields, B.A, Brenner, M.B, Mariuzza, R.A.
Deposit date:1997-10-19
Release date:1998-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor.
Nature, 391, 1998
4Z0X
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BU of 4z0x by Molmil
Structure of Hepatitis C Virus Envelope glycoprotein E2 antigenic region 434-446 bound to the broadly neutralizing antibody HC26AM
Descriptor: Antibody HC26AM heavy chain variable domain, Antibody HC26AM light chain variable domain, HCV E2 Antigen (residues 432-446)
Authors:Rangarajan, S, Shahid, S, Mariuzza, R.A.
Deposit date:2015-03-26
Release date:2016-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.
Hepatology, 64, 2016

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