4UTV
 
 | | Crystal structure of zebrafish Sirtuin 5 in complex with 3-phenyl- succinylated CPS1-peptide | | 分子名称: | (2R)-2-phenylbutanedioic acid, (2S)-2-phenylbutanedioic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Pannek, M, Gertz, M, Steegborn, C. | | 登録日 | 2014-07-23 | | 公開日 | 2014-08-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4V8W
 | | Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex | | 分子名称: | FLAVIN MONONUCLEOTIDE, TYPE-I FATTY ACID SYNTHASE | | 著者 | Ciccarelli, L, Connell, S.R, Enderle, M, Mills, D.J, Vonck, J, Grininger, M. | | 登録日 | 2013-04-18 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (17.5 Å) | | 主引用文献 | Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21, 2013
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1DO2
 | | TRIGONAL CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (HEAT SHOCK LOCUS U) | | 著者 | Bochtler, M, Hartmann, C, Song, H.K, Bourenkov, G.P, Bartunik, H.D. | | 登録日 | 1999-12-18 | | 公開日 | 2000-02-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | The structures of HsIU and the ATP-dependent protease HsIU-HsIV.
Nature, 403, 2000
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4U2J
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4UBD
 | | Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | | 著者 | Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J. | | 登録日 | 2014-08-12 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Nat Commun, 6, 2015
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1DVE
 | | CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME | | 分子名称: | HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Omata, Y, Kakuta, Y, Sakamoto, H, Noguchi, M, Fukuyama, K. | | 登録日 | 2000-01-20 | | 公開日 | 2000-04-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of rat heme oxygenase-1 in complex with heme.
FEBS Lett., 471, 2000
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1DZC
 | | High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures | | 分子名称: | FIBROBLAST GROWTH FACTOR 1 | | 著者 | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | | 登録日 | 2000-02-24 | | 公開日 | 2000-03-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
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1E4L
 | | Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZM Glu191Asp | | 分子名称: | BETA-GLUCOSIDASE, CHLOROPLASTIC, GLYCEROL | | 著者 | Czjzek, M, Cicek, M, Bevan, D.R, Henrissat, B, Esen, A. | | 登録日 | 2000-07-10 | | 公開日 | 2000-12-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Mechanism of Substrate (Aglycone) Specificity in Beta -Glucosidases is Revealed by Crystal Structures of Mutant Maize Beta -Glucosidase-Dimboa, -Dimboaglc, and -Dhurrin Complexes
Proc.Natl.Acad.Sci.USA, 97, 2000
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1E4N
 | | Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the natural aglycone DIMBOA | | 分子名称: | 2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE, BETA-GLUCOSIDASE | | 著者 | Czjzek, M, Cicek, M, Bevan, D.R, Zamboni, V, Henrissat, B, Esen, A. | | 登録日 | 2000-07-11 | | 公開日 | 2000-12-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Mechanism of Substrate (Aglycone) Specificity in Beta -Glucosidases is Revealed by Crystal Structures of Mutant Maize Beta -Glucosidase-Dimboa, -Dimboaglc, and -Dhurrin Complexes
Proc.Natl.Acad.Sci.USA, 97, 2000
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1DZD
 | | High resolution structure of acidic fibroblast growth factor (27-154), 24 NMR structures | | 分子名称: | ACIDIC FIBROBLAST GROWTH FACTOR | | 著者 | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | | 登録日 | 2000-02-24 | | 公開日 | 2000-03-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
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1E6U
 | | GDP 4-keto-6-deoxy-D-mannose epimerase reductase | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... | | 著者 | Rosano, C, Izzo, G, Bolognesi, M. | | 登録日 | 2000-08-23 | | 公開日 | 2000-10-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
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1EQR
 | | CRYSTAL STRUCTURE OF FREE ASPARTYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI | | 分子名称: | ASPARTYL-TRNA SYNTHETASE, MAGNESIUM ION | | 著者 | Rees, B, Webster, G, Delarue, M, Boeglin, M, Moras, D. | | 登録日 | 2000-04-06 | | 公開日 | 2000-06-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Aspartyl tRNA-synthetase from Escherichia coli: flexibility and adaptability to the substrates.
J.Mol.Biol., 299, 2000
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4WCC
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation P225G | | 分子名称: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-MONOPHOSPHATE, CHLORIDE ION | | 著者 | Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2014-09-04 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
Sci Rep, 5, 2015
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4WDB
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation R307Q, complexed with 2'-AMP | | 分子名称: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-MONOPHOSPHATE, CHLORIDE ION | | 著者 | Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2014-09-08 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
Sci Rep, 5, 2015
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4UT3
 | | X-ray structure of the human PP1 gamma catalytic subunit treated with hydrogen peroxide | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | | 著者 | Zeh Silva, M, Kopec, J, Fotinou, D, Steiner, R.A. | | 登録日 | 2014-07-17 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling.
Embo J., 35, 2016
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1EK3
 | | KAPPA-4 IMMUNOGLOBULIN VL, REC | | 分子名称: | CALCIUM ION, CHLORIDE ION, KAPPA-4 IMMUNOGLOBULIN LIGHT CHAIN VL | | 著者 | Pokkuluri, P.R, Huang, D.-B, Raffen, R, Stevens, F.J, Schiffer, M. | | 登録日 | 2000-03-06 | | 公開日 | 2001-03-06 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Structure of Amyloidogenic Kappa-4 Immunoglobulin VL, REC
To be Published
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1E56
 | | Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the natural substrate DIMBOA-beta-D-glucoside | | 分子名称: | 2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE, BETA-GLUCOSIDASE, beta-D-glucopyranose | | 著者 | Czjzek, M, Cicek, M, Bevan, D.R, Zamboni, V, Henrissat, B, Esen, A. | | 登録日 | 2000-07-18 | | 公開日 | 2000-12-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Mechanism of Substrate (Aglycone) Specificity in Beta -Glucosidases is Revealed by Crystal Structures of Mutant Maize Beta -Glucosidase- Dimboa, -Dimboaglc, and -Dhurrin Complexes
Proc.Natl.Acad.Sci.USA, 97, 2000
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1EBC
 | | SPERM WHALE MET-MYOGLOBIN:CYANIDE COMPLEX | | 分子名称: | CYANIDE ION, PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Rosano, C, Ascenzi, P, Rizzi, M, Losso, R, Bolognesi, M. | | 登録日 | 1999-03-04 | | 公開日 | 1999-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: an x-ray crystallographic study.
Biophys.J., 77, 1999
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4WBL
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation F235A | | 分子名称: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase, CHLORIDE ION, GLYCEROL | | 著者 | Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2014-09-03 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
Sci Rep, 5, 2015
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4UQG
 | | A new bio-isosteric base pair based on reversible bonding | | 分子名称: | 5'-D(*AP*GP*GP*GP*A SAYP*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*C T0TP*TP*CP*CP*CP*TP)-3', DNA POLYMERASE, ... | | 著者 | Tomas-Gamasa, M, Serdjukov, S, Su, M, Mueller, M, Carell, T. | | 登録日 | 2014-06-23 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | "Post-it" type connected DNA created with a reversible covalent cross-link.
Angew. Chem. Int. Ed. Engl., 54, 2015
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1E55
 | | Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the competitive inhibitor dhurrin | | 分子名称: | (2S)-HYDROXY(4-HYDROXYPHENYL)ETHANENITRILE, BETA-GLUCOSIDASE, beta-D-glucopyranose | | 著者 | Czjzek, M, Cicek, M, Bevan, D.R, Zamboni, V, Henrissat, B, Esen, A. | | 登録日 | 2000-07-18 | | 公開日 | 2000-12-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The mechanism of substrate (aglycone) specificity in beta-glucosidases is revealed by crystal structures of mutant maize beta-glucosidase-DIMBOA, -DIMBOAGlc, and -dhurrin complexes.
Proc. Natl. Acad. Sci. U.S.A., 97, 2000
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1EJB
 | | LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | 5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID, LUMAZINE SYNTHASE | | 著者 | Meining, W, Mortl, S, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | | 登録日 | 2000-03-02 | | 公開日 | 2001-03-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue.
J.Mol.Biol., 299, 2000
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1EI4
 | | B-DNA DODECAMER CGCGAAT(TLC)CGCG WITH INCORPORATED [3.3.0]BICYCLO-ARABINO-THYMINE-5'-PHOSPHATE | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TLC)P*(TLC)P*CP*GP*CP*G)-3'), MAGNESIUM ION, SPERMINE | | 著者 | Minasov, G, Teplova, M, Nielsen, P, Wengel, J, Egli, M. | | 登録日 | 2000-02-24 | | 公開日 | 2000-03-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA.
Biochemistry, 39, 2000
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4WDF
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, complexed with 2',5'-ADP | | 分子名称: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-5'-DIPHOSPHATE | | 著者 | Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2014-09-08 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
Sci Rep, 5, 2015
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4WDG
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, complexed with 2',5'-ADP | | 分子名称: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-5'-DIPHOSPHATE | | 著者 | Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2014-09-08 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
Sci Rep, 5, 2015
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