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2B8A
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BU of 2b8a by Molmil
High Resolution Structure of the HDGF PWWP Domain
Descriptor: Hepatoma-derived growth factor
Authors:Lukasik, S.M, Cierpicki, T, Borloz, M, Grembecka, J, Everett, A, Bushweller, J.H.
Deposit date:2005-10-06
Release date:2005-12-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:High resolution structure of the HDGF PWWP domain: a potential DNA binding domain.
Protein Sci., 15, 2006
1WQ6
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BU of 1wq6 by Molmil
The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
Descriptor: AML1-ETO
Authors:Liu, Y, Cheney, M.D, Chruszcz, M, Lukasik, S.M, Hartman, K.L, Laue, T.M, Dauter, Z, Minor, W, Speck, N.A, Bushweller, J.H.
Deposit date:2004-09-23
Release date:2005-10-04
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity
Cancer Cell, 9, 2006
2J6W
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BU of 2j6w by Molmil
R164N mutant of the RUNX1 Runt domain
Descriptor: CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Grembecka, J, Zhe, L, Lukasik, S.M, Liu, Y, Bielnicka, I, Bushweller, J.H, Speck, N.A.
Deposit date:2006-10-04
Release date:2007-10-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation.
J.Mol.Biol., 364, 2006
2KKF
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Solution structure of MLL CXXC domain in complex with palindromic CPG DNA
Descriptor: 5'-D(*CP*CP*CP*TP*GP*CP*GP*CP*AP*GP*GP*G)-3', Histone-lysine N-methyltransferase HRX, ZINC ION
Authors:Cierpicki, T, Riesbeck, J.E, Grembecka, J.E, Lukasik, S.M, Popovic, R, Omonkowska, M, Shultis, D.S, Zeleznik-Le, N.J, Bushweller, J.H.
Deposit date:2009-06-18
Release date:2009-12-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.
Nat.Struct.Mol.Biol., 17, 2010
2K74
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Solution NMR structure of DsbB-ubiquinone complex
Descriptor: Disulfide bond formation protein B, UBIQUINONE-2
Authors:Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H.
Deposit date:2008-08-01
Release date:2008-10-07
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.
Mol.Cell, 31, 2008
2K73
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Solution NMR structure of integral membrane protein DsbB
Descriptor: Disulfide bond formation protein B
Authors:Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H.
Deposit date:2008-08-01
Release date:2008-10-07
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.
Mol.Cell, 31, 2008
2JYI
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Solution structure of MLL CXXC domain
Descriptor: ZINC ION, Zinc finger protein HRX
Authors:Cierpicki, T, Bushweller, J.H.
Deposit date:2007-12-13
Release date:2008-12-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for maintenance of unmethylated CpG elements by the CXXC domain of MLL and its critical contributions to MLL-AF9 immortalization activity
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