1XFP
 
 | | Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme | | Descriptor: | FORMIC ACID, Lysozyme C, heavy chain antibody | | Authors: | De Genst, E, Handelberg, F, Van Meirhaeghe, A, Vynck, S, Loris, R, Wyns, L, Muyldermans, S. | | Deposit date: | 2004-09-15 | | Release date: | 2004-09-28 | | Last modified: | 2013-02-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Chemical Basis for the Affinity Maturation of a Camel Single Domain Antibody
J.Biol.Chem., 279, 2004
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1O9V
 | | F17-aG lectin domain from Escherichia coli in complex with a selenium carbohydrate derivative | | Descriptor: | F17-AG LECTIN DOMAIN, methyl 2-acetamido-2-deoxy-1-seleno-beta-D-glucopyranoside | | Authors: | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | Deposit date: | 2002-12-20 | | Release date: | 2003-05-29 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
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1O9Z
 | | F17-aG lectin domain from Escherichia coli (ligand free) | | Descriptor: | F17-AG LECTIN DOMAIN | | Authors: | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | Deposit date: | 2002-12-23 | | Release date: | 2003-05-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
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3HS2
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1YC8
 | | cAbAn33- Y37V/E44G/R45L triple mutant | | Descriptor: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | Authors: | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | Deposit date: | 2004-12-22 | | Release date: | 2005-06-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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3HOH
 | | RIBONUCLEASE T1 (THR93GLN MUTANT) COMPLEXED WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | Deposit date: | 1998-09-11 | | Release date: | 1998-09-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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1YC7
 | | cAbAn33 VHH fragment against VSG | | Descriptor: | SULFATE ION, anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | Authors: | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | Deposit date: | 2004-12-22 | | Release date: | 2005-06-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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3HRY
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1ZPL
 | | E. coli F17a-G lectin domain complex with GlcNAc(beta1-O)Me | | Descriptor: | F17a-G, methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside | | Authors: | Buts, L, Wellens, A, Van Molle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. | | Deposit date: | 2005-05-17 | | Release date: | 2006-05-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
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1ZK5
 | | Escherichia coli F17fG lectin domain complex with N-acetylglucosamine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17G adhesin subunit | | Authors: | Buts, L, Wellens, A, Van Molle, I, De Genst, E, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. | | Deposit date: | 2005-05-02 | | Release date: | 2006-05-02 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
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2ENR
 | | CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH CADMIUM HAVING A CADMIUM ION BOUND IN BOTH THE S1 SITE AND THE S2 SITE | | Descriptor: | CADMIUM ION, CONCANAVALIN A | | Authors: | Bouckaert, J, Loris, R, Wyns, L. | | Deposit date: | 1998-07-14 | | Release date: | 1999-02-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Zinc/calcium- and cadmium/cadmium-substituted concanavalin A: interplay of metal binding, pH and molecular packing.
Acta Crystallogr.,Sect.D, 56, 2000
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1QDO
 | | MAN(APLHA1-3)MAN(ALPHA1-O)METHYL CONCANAVALIN A COMPLEX | | Descriptor: | CALCIUM ION, MANGANESE (II) ION, PROTEIN (CONCANAVALIN A), ... | | Authors: | Bouckaert, J, Loris, R, Wyns, L. | | Deposit date: | 1999-05-24 | | Release date: | 1999-10-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A.
J.Biol.Chem., 274, 1999
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1QDC
 | | MAN(APLHA1-6)MAN(ALPHA1-O)METHYL CONCANAVALIN A COMPLEX | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANGANESE (II) ION, ... | | Authors: | Bouckaert, J, Loris, R, Wyns, L. | | Deposit date: | 1998-07-14 | | Release date: | 1999-10-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A.
J.Biol.Chem., 274, 1999
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7B22
 | | Vibrio cholerae ParD2 Antitoxin | | Descriptor: | Antitoxin ParD | | Authors: | Garcia-Rodriguez, G, Loris, R. | | Deposit date: | 2020-11-25 | | Release date: | 2021-10-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.08 Å) | | Cite: | Entropic pressure controls the oligomerization of the Vibrio cholerae ParD2 antitoxin.
Acta Crystallogr D Struct Biol, 77, 2021
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1MMC
 | | 1H NMR STUDY OF THE SOLUTION STRUCTURE OF AC-AMP2 | | Descriptor: | ANTIMICROBIAL PEPTIDE 2 | | Authors: | Martins, J.C, Maes, D, Loris, R, Pepermans, H.A.M, Wyns, L, Willem, R, Verheyden, P. | | Deposit date: | 1995-10-25 | | Release date: | 1996-03-08 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | H NMR study of the solution structure of Ac-AMP2, a sugar binding antimicrobial protein isolated from Amaranthus caudatus.
J.Mol.Biol., 258, 1996
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1CES
 | | CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH ZINC HAVE A ZINC ION BOUND IN THE S1 SITE | | Descriptor: | CONCANAVALIN A, ZINC ION | | Authors: | Bouckaert, J, Loris, R, Poortmans, F, Wyns, L. | | Deposit date: | 1996-02-15 | | Release date: | 1997-02-15 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
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1G8W
 | | IMPROVED STRUCTURE OF PHYTOHEMAGGLUTININ-L FROM THE KIDNEY BEAN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCOAGGLUTINATING PHYTOHEMAGGLUTININ, ... | | Authors: | Buts, L, Hamelryck, T.W, Dao-Thi, M, Loris, R, Wyns, L, Etzler, M.E. | | Deposit date: | 2000-11-21 | | Release date: | 2000-12-13 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Weak protein-protein interactions in lectins: the crystal structure of a vegetative lectin from the legume Dolichos biflorus.
J.Mol.Biol., 309, 2001
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1BJQ
 | | THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH ADENINE | | Descriptor: | ADENINE, CALCIUM ION, LECTIN, ... | | Authors: | Hamelryck, T.W, Loris, R, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M. | | Deposit date: | 1998-06-26 | | Release date: | 1998-12-30 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
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1ENR
 | | CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC AND CALCIUM HAVING A ZINC ION BOUND IN THE S1 SITE AND A CALCIUM ION BOUND IN THE S2 SITE | | Descriptor: | CALCIUM ION, CONCANAVALIN A, ZINC ION | | Authors: | Bouckaert, J, Loris, R, Poortmans, F, Wyns, L. | | Deposit date: | 1996-03-20 | | Release date: | 1996-08-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
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1ENS
 | | CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH COBALT HAVING A COBALT ION BOUND IN THE S1 SITE | | Descriptor: | COBALT (II) ION, CONCANAVALIN A | | Authors: | Bouckaert, J, Loris, R, Poortmans, F, Wyns, L. | | Deposit date: | 1996-03-20 | | Release date: | 1996-08-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
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1ENQ
 | | CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC HAVING A ZINC ION BOUND IN THE S1 SITE | | Descriptor: | CONCANAVALIN A, ZINC ION | | Authors: | Bouckaert, J, Loris, R, Poortmans, F, Wyns, L. | | Deposit date: | 1996-03-20 | | Release date: | 1996-08-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A.
J.Biol.Chem., 271, 1996
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3DIE
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3EAK
 | | NbBCII10 humanized (FGLA mutant) | | Descriptor: | NbBCII10-FGLA, SULFATE ION | | Authors: | Vincke, C, Loris, R, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | | Deposit date: | 2008-08-26 | | Release date: | 2008-12-02 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.
J.Biol.Chem., 2008
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3DWT
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3ENR
 | | ZINC-CALCIUM CONCANAVALIN A AT PH 6.15 | | Descriptor: | CALCIUM ION, Concanavalin-A, ZINC ION | | Authors: | Bouckaert, J, Loris, R, Wyns, L. | | Deposit date: | 1999-02-11 | | Release date: | 2000-09-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Zinc/calcium- and cadmium/cadmium-substituted concanavalin A: interplay of metal binding, pH and molecular packing.
Acta Crystallogr.,Sect.D, 56, 2000
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