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6N7T
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BU of 6n7t by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III)
Descriptor: DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N7S
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BU of 6n7s by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II)
Descriptor: DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N7V
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BU of 6n7v by Molmil
Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)
Descriptor: DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N7N
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BU of 6n7n by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I)
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-11-27
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N9W
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BU of 6n9w by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)
Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-12-04
Release date:2019-03-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
5W84
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BU of 5w84 by Molmil
CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 4)
Descriptor: 4-(benzylamino)-6-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]pyridine-3-carboxamide, Interleukin-1 receptor-associated kinase 4
Authors:Sack, J.S.
Deposit date:2017-06-21
Release date:2017-10-11
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5XWW
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BU of 5xww by Molmil
Substrate-bound Structure of G355T/Q364H mutant of a Ketoreductase from amphotericin Polyketide Synthases
Descriptor: AmphB, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl] (2R)-2-methyl-3-oxidanylidene-pentanethioate
Authors:Liu, C, Zheng, J.
Deposit date:2017-06-30
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.
J. Struct. Biol., 203, 2018
5XWV
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BU of 5xwv by Molmil
Substrate-bound Structure of a Ketoreductase from the Second Module of the amphotericin Polyketide Synthases
Descriptor: AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl] (2R)-2-methyl-3-oxidanylidene-pentanethioate
Authors:Liu, C, Zheng, J.
Deposit date:2017-06-30
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.
J. Struct. Biol., 203, 2018
6BJJ
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BU of 6bjj by Molmil
Human ABO(H) blood group glycosyltransferase GTB D302A mutant
Descriptor: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase)
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
6BJI
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BU of 6bji by Molmil
Human ABO(H) blood group glycosyltransferase GTA D302C mutant
Descriptor: GLYCEROL, Histo-blood group ABO system transferase
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
6BJK
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BU of 6bjk by Molmil
Human ABO(H) blood group glycosyltransferase GTB D302C mutant
Descriptor: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
6BJL
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BU of 6bjl by Molmil
Human ABO(H) blood group glycosyltransferase GTB D302L mutant
Descriptor: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
6BJM
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BU of 6bjm by Molmil
Human ABO(H) blood group glycosyltransferase GTB R188K mutant
Descriptor: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
7CM3
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BU of 7cm3 by Molmil
Cryo-EM structure of human NALCN in complex with FAM155A
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wu, J, Yan, Z, Ke, M.
Deposit date:2020-07-24
Release date:2020-11-11
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the human sodium leak channel NALCN in complex with FAM155A.
Nat Commun, 11, 2020
7CE2
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BU of 7ce2 by Molmil
The Crystal structure of TeNT Hc complexed with neutralizing antibody
Descriptor: Tetanus toxin, neutralizing antibody heavy chain, neutralizing antibody light chain
Authors:Wang, X, Wang, Y, Wu, C, Yu, J, Liao, H.
Deposit date:2020-06-21
Release date:2021-04-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural basis of tetanus toxin neutralization by native human monoclonal antibodies.
Cell Rep, 35, 2021
7VPD
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BU of 7vpd by Molmil
Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with one Zur dimers
Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, X, Zheng, J.
Deposit date:2021-10-15
Release date:2022-08-03
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
7VO0
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BU of 7vo0 by Molmil
Streptomyces coelicolor zinc uptake regulator complexed with zinc and DNA (trimer of dimers)
Descriptor: DNA_NT (84-MER), DNA_T (84-MER), Putative metal uptake regulation protein, ...
Authors:Yang, X, Zheng, J.
Deposit date:2021-10-12
Release date:2022-08-03
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
7VO9
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BU of 7vo9 by Molmil
Streptomyces coelicolor zinc uptake regulator complexed with zinc and DNA (dimer of dimers)
Descriptor: DNA (84-MER), Putative metal uptake regulation protein, ZINC ION
Authors:Yang, X, Zheng, J.
Deposit date:2021-10-13
Release date:2022-08-03
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
7VPZ
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BU of 7vpz by Molmil
Cryo-EM structure of Streptomyces coelicolor transcription initial complex with one Zur dimer
Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, X, Zheng, J.
Deposit date:2021-10-18
Release date:2022-08-03
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
7VWK
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BU of 7vwk by Molmil
The product template domain of AviM
Descriptor: Polyketide synthase
Authors:Feng, Y, Yang, X, Zheng, J.
Deposit date:2021-11-10
Release date:2022-06-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases.
Commun Biol, 5, 2022
7WVZ
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BU of 7wvz by Molmil
CalA3_modular PKS_KS-AT-DH-KR
Descriptor: Beta-ketoacyl-acyl-carrier-protein synthase I
Authors:Wang, J, Wang, Z.
Deposit date:2022-02-12
Release date:2023-02-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:C-N bond formation by a polyketide synthase.
Nat Commun, 14, 2023
7X76
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BU of 7x76 by Molmil
Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with two Zur dimers
Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, X, Zheng, J.
Deposit date:2022-03-09
Release date:2022-08-03
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
7X74
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BU of 7x74 by Molmil
Cryo-EM structure of Streptomyces coelicolor transcription initial complex with two Zur dimers.
Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, X, Zheng, J.
Deposit date:2022-03-09
Release date:2022-08-03
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022
7X75
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BU of 7x75 by Molmil
Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with three Zur dimers
Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, X, Zheng, J.
Deposit date:2022-03-09
Release date:2022-08-03
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Nucleic Acids Res., 50, 2022

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數據於2024-05-22公開中

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