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6XB7
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BU of 6xb7 by Molmil
IRES-targeting Small Molecule Inhibits Enterovirus 71 Replication via Allosteric Stabilization of a Ternary Complex
Descriptor: 3-amino-N-(diaminomethylidene)-5-(dimethylamino)-6-(phenylethynyl)pyrazine-2-carboxamide, RNA (41-MER)
Authors:Tolbert, B.S, Davila, J, Sugarman, A.L, Chiu, L.Y.
Deposit date:2020-06-05
Release date:2020-09-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex.
Nat Commun, 11, 2020
5V16
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BU of 5v16 by Molmil
HnRNP A1 Alters the Conformation of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation
Descriptor: RNA (41-MER)
Authors:Tolbert, M, Morgan, C.E, Tolbert, B.S.
Deposit date:2017-03-01
Release date:2017-07-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation.
J. Mol. Biol., 429, 2017
8YV9
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BU of 8yv9 by Molmil
Crystal structure of Caenorhabditis elegans HIM-8 ZF1-2-CTD domain in complex with Chromosome X pairing center
Descriptor: C2H2-type domain-containing protein, DNA (5'-D(*TP*GP*CP*AP*CP*TP*GP*AP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*TP*CP*AP*GP*TP*GP*CP*A)-3'), ...
Authors:Li, F.D, Li, M.L.
Deposit date:2024-03-28
Release date:2024-12-11
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural basis for C. elegans pairing center DNA binding specificity by the ZIM/HIM-8 family proteins.
Nat Commun, 15, 2024
8YVA
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BU of 8yva by Molmil
Crystal structure of Caenorhabditis elegans ZIM-2 ZF1-2-CTD domain in complex with Chromosome V pairing center
Descriptor: C2H2-type domain-containing protein, DNA (5'-D(*AP*GP*CP*AP*GP*CP*GP*CP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*GP*CP*GP*CP*TP*GP*CP*T)-3'), ...
Authors:Li, F.D, Li, M.L.
Deposit date:2024-03-28
Release date:2024-12-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for C. elegans pairing center DNA binding specificity by the ZIM/HIM-8 family proteins.
Nat Commun, 15, 2024
8YVB
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BU of 8yvb by Molmil
Crystal structure of Caenorhabditis elegans ZIM-1 ZF1-2-CTD domain in complex with Chromosome II/III pairing center
Descriptor: C2H2-type domain-containing protein, DNA (5'-D(*TP*TP*GP*GP*TP*CP*TP*GP*CP*TP*A)-3'), DNA (5'-D(P*AP*GP*CP*AP*GP*AP*CP*CP*AP*A)-3'), ...
Authors:Li, F.D, Li, M.L.
Deposit date:2024-03-28
Release date:2024-12-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for C. elegans pairing center DNA binding specificity by the ZIM/HIM-8 family proteins.
Nat Commun, 15, 2024
6M1K
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BU of 6m1k by Molmil
USP7 in complex with a novel inhibitor
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate
Authors:Liu, S.J, Zhou, X.Y, Li, M.L, Sun, H.B, Wen, X.A.
Deposit date:2020-02-26
Release date:2021-03-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.255 Å)
Cite:N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies.
Eur.J.Med.Chem., 199, 2020
5V17
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BU of 5v17 by Molmil
HnRNP A1 Alters the Conformation of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation
Descriptor: RNA (41-MER)
Authors:Tolbert, M, Morgan, C.E, Tolbert, B.S.
Deposit date:2017-03-01
Release date:2017-07-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation.
J. Mol. Biol., 429, 2017

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