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3ZYS
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BU of 3zys by Molmil
Human dynamin 1 deltaPRD polymer stabilized with GMPPCP
分子名称: DYNAMIN-1, INTERFERON-INDUCED GTP-BINDING PROTEIN MX1
著者Chappie, J.S, Mears, J.A, Fang, S, Leonard, M, Schmid, S.L, Milligan, R.A, Hinshaw, J.E, Dyda, F.
登録日2011-08-24
公開日2011-10-12
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (12.2 Å)
主引用文献A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke.
Cell(Cambridge,Mass.), 147, 2011
3ZYC
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BU of 3zyc by Molmil
DYNAMIN 1 GTPASE GED FUSION DIMER COMPLEXED WITH GMPPCP
分子名称: DYNAMIN-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Chappie, J.S, Mears, J.A, Fang, S, Leonard, M, Schmid, S.L, Milligan, R.A, Hinshaw, J.E, Dyda, F.
登録日2011-08-22
公開日2011-10-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke.
Cell(Cambridge,Mass.), 147, 2011
2X2F
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BU of 2x2f by Molmil
Dynamin 1 GTPase dimer, short axis form
分子名称: DYNAMIN-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Chappie, J.S, Acharya, S, Leonard, M, Schmid, S.L, Dyda, F.
登録日2010-01-13
公開日2010-04-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献G Domain Dimerization Controls Dynamin'S Assembly-Stimulated Gtpase Activity.
Nature, 465, 2010
1P45
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BU of 1p45 by Molmil
Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN
著者Kuo, M.R, Morbidoni, H.R, Alland, D, Sneddon, S.F, Gourlie, B.B, Staveski, M.M, Leonard, M, Gregory, J.S, Janjigian, A.D, Yee, C, Musser, J.M, Kreiswirth, B.N, Iwamoto, H, Perozzo, R, Jacobs Jr, W.R, Sacchettini, J.C, Fidock, D.A, TB Structural Genomics Consortium (TBSGC)
登録日2003-04-21
公開日2003-09-16
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data.
J.Biol.Chem., 278, 2003
1P44
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BU of 1p44 by Molmil
Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data
分子名称: 5-{[4-(9H-FLUOREN-9-YL)PIPERAZIN-1-YL]CARBONYL}-1H-INDOLE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kuo, M.R, Morbidoni, H.R, Alland, D, Sneddon, S.F, Gourlie, B.B, Staveski, M.M, Leonard, M, Gregory, J.S, Janjigian, A.D, Yee, C, Musser, J.M, Kreiswirth, B, Iwamoto, H, Perozzo, R, Jacobs Jr, W.R, Sacchettini, J.C, Fidock, D.A, TB Structural Genomics Consortium (TBSGC)
登録日2003-04-21
公開日2003-09-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data.
J.Biol.Chem., 278, 2003
2X2E
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BU of 2x2e by Molmil
Dynamin GTPase dimer, long axis form
分子名称: DYNAMIN-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Chappie, J.S, Acharya, S, Leonard, M, Schmid, S.L, Dyda, F.
登録日2010-01-12
公開日2010-04-28
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献G Domain Dimerization Controls Dynamin'S Assembly-Stimulated Gtpase Activity.
Nature, 465, 2010
2AKA
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BU of 2aka by Molmil
Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus
分子名称: Dynamin-1, LINKER, myosin II heavy chain
著者Reubold, T.F, Eschenburg, S, Becker, A, Leonard, M, Schmid, S.L, Vallee, R.B, Kull, F.J, Manstein, D.J.
登録日2005-08-03
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the GTPase domain of rat dynamin 1.
Proc.Natl.Acad.Sci.Usa, 102, 2005
4ZYF
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BU of 4zyf by Molmil
Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: Hdm2 (MDM2) complexed with NVP-CGM097
分子名称: (S)-1-(4-chlorophenyl)-7-isopropoxy-6-methoxy-2-(4-(methyl(((1r,4S)-4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl)methyl)amino)phenyl)-1,2-dihydroisoquinolin-3(4H)-one, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2
著者Kallen, J.
登録日2015-05-21
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors.
J.Med.Chem., 58, 2015
4ZYI
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BU of 4zyi by Molmil
Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: Hdm2 (MDM2) complexed with cpd2
分子名称: (S)-7-((R)-sec-butoxy)-1-(4-chlorophenyl)-6-methoxy-2-(4-(methyl(pyridin-4-ylmethyl)amino)phenyl)-1,2-dihydroisoquinolin-3(4H)-one, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2
著者Kallen, J.
登録日2015-05-21
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors.
J.Med.Chem., 58, 2015
5FG1
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BU of 5fg1 by Molmil
Structure of the conserved yeast listerin (Ltn1) selenomethionine-substituted N-terminal domain, TRIGONAL FORM
分子名称: E3 ubiquitin-protein ligase listerin, POTASSIUM ION
著者Doamekpor, S.K, Lima, C.D.
登録日2015-12-19
公開日2016-07-06
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits.
Proc.Natl.Acad.Sci.USA, 113, 2016
5FG0
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BU of 5fg0 by Molmil
Structure of the conserved yeast listerin (Ltn1) N-terminal domain, MONOCLINIC FORM
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase listerin, POTASSIUM ION
著者Doamekpor, S.K, Lima, C.D.
登録日2015-12-19
公開日2016-07-06
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits.
Proc.Natl.Acad.Sci.USA, 113, 2016

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件を2024-05-08に公開中

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