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4X3H
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BU of 4x3h by Molmil
CRYSTAL STRUCTURE OF ARC N-LOBE COMPLEXED WITH STARGAZIN PEPTIDE
Descriptor: Activity-regulated cytoskeleton-associated protein, VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT
Authors:zhang, W, ward, m, leahy, d, worley, p.
Deposit date:2014-11-30
Release date:2015-06-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
Neuron, 86, 2015
4X3I
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BU of 4x3i by Molmil
The crystal structure of Arc N-lobe complexed with CAMK2A fragment
Descriptor: Activity-regulated cytoskeleton-associated protein, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA
Authors:Zhang, W, Ward, M, Leahy, D, Worley, P.
Deposit date:2014-11-30
Release date:2015-06-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
Neuron, 86, 2015
5WB7
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BU of 5wb7 by Molmil
Crystal structure of the epidermal growth factor receptor extracellular region in complex with epiregulin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Freed, D.M, Bessman, N.J, Ferguson, K.M, Lemmon, M.A.
Deposit date:2017-06-28
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.941 Å)
Cite:EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics.
Cell, 171, 2017
5WB8
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BU of 5wb8 by Molmil
Crystal structure of the epidermal growth factor receptor extracellular region in complex with epigen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Epigen, ...
Authors:Bessman, N.J, Freed, D.M, Moore, J.O, Ferguson, K.M, Lemmon, M.A.
Deposit date:2017-06-28
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics.
Cell, 171, 2017
1NQL
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BU of 1nql by Molmil
Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ferguson, K.M, Lemmon, M.A.
Deposit date:2003-01-21
Release date:2003-03-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:EGF activates its receptor by removing interactions that auto-inhibit ectodomain dimerization
Mol.Cell, 11, 2003
3BCE
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BU of 3bce by Molmil
Crystal structure of the ErbB4 kinase
Descriptor: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Receptor tyrosine-protein kinase erbB-4, ...
Authors:Qiu, C.
Deposit date:2007-11-12
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3BCZ
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BU of 3bcz by Molmil
Crystal structure of Memo
Descriptor: GLYCEROL, Protein MEMO1
Authors:Qiu, C.
Deposit date:2007-11-13
Release date:2007-11-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Memo Is Homologous to Nonheme Iron Dioxygenases and Binds an ErbB2-derived Phosphopeptide in Its Vestigial Active Site.
J.Biol.Chem., 283, 2008
3BBW
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BU of 3bbw by Molmil
crystal structure of the ErbB4 kinase in its inactive conformation
Descriptor: Receptor tyrosine-protein kinase erbB-4
Authors:Qiu, C.
Deposit date:2007-11-11
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3BD0
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BU of 3bd0 by Molmil
Crystal structure of Memo, form II
Descriptor: DI(HYDROXYETHYL)ETHER, Protein MEMO1
Authors:Qiu, C.
Deposit date:2007-11-13
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Memo Is Homologous to Nonheme Iron Dioxygenases and Binds an ErbB2-derived Phosphopeptide in Its Vestigial Active Site.
J.Biol.Chem., 283, 2008
3BBT
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BU of 3bbt by Molmil
crystal structure of the ErbB4 kinase in complex with lapatinib
Descriptor: N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE, Receptor tyrosine-protein kinase erbB-4
Authors:Qiu, C.
Deposit date:2007-11-11
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
1LZ5
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BU of 1lz5 by Molmil
STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME
Descriptor: CHLORIDE ION, HUMAN LYSOZYME
Authors:Matsushima, M, Inaka, K, Yamada, T, Sekiguchi, K, Kikuchi, M.
Deposit date:1993-02-03
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme.
J.Biol.Chem., 268, 1993
1LZ6
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BU of 1lz6 by Molmil
STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME
Descriptor: CHLORIDE ION, HUMAN LYSOZYME
Authors:Matsushima, M, Inaka, K, Yamada, T, Sekiguchi, K, Kikuchi, M.
Deposit date:1993-02-03
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analyses of the Arg-Gly-Asp sequence introduced into human lysozyme.
J.Biol.Chem., 268, 1993
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