1E96
 
 | | Structure of the Rac/p67phox complex | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ... | | 著者 | Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K. | | 登録日 | 2000-10-10 | | 公開日 | 2000-11-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the TPR domain of p67phox in complex with Rac.GTP.
Mol.Cell, 6, 2000
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5TKY
 | | Crystal structure of the co-translational Hsp70 chaperone Ssb in the ATP-bound, open conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein | | 著者 | Gumiero, A, Gese, G.V, Weyer, F.A, Lapouge, K, Sinning, I. | | 登録日 | 2016-10-10 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain.
Nat Commun, 7, 2016
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1NG2
 | | Structure of autoinhibited p47phox | | 分子名称: | Neutrophil cytosolic factor 1 | | 著者 | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | | 登録日 | 2002-12-16 | | 公開日 | 2003-05-20 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
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1OV3
 | | Structure of the p22phox-p47phox complex | | 分子名称: | Flavocytochrome b558 alpha polypeptide, Neutrophil cytosol factor 1 | | 著者 | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | | 登録日 | 2003-03-25 | | 公開日 | 2003-05-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
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2JPP
 | | Structural basis of RsmA/CsrA RNA recognition: Structure of RsmE bound to the Shine-Dalgarno sequence of hcnA mRNA | | 分子名称: | RNA (5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*CP*GP*GP*AP*UP*GP*AP*AP*GP*CP*CP*C)-3'), Translational repressor | | 著者 | Schubert, M, Lapouge, K, Duss, O, Oberstrass, F.C, Jelesarov, I, Haas, D, Allain, F.H.-T. | | 登録日 | 2007-05-21 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA
Nat.Struct.Mol.Biol., 14, 2007
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6Y31
 | | NG domain of human SRP54 T117 deletion mutant | | 分子名称: | Signal recognition particle 54 kDa protein | | 著者 | Juaire, K.D, Lapouge, K, Becker, M.M.M, Kotova, I, Haas, M, Carapito, R, Wild, K, Bahram, S, Sinning, I. | | 登録日 | 2020-02-17 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (4.001 Å) | | 主引用文献 | Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
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6SR6
 | | Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ... | | 著者 | Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I. | | 登録日 | 2019-09-05 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Nat Commun, 11, 2020
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6TGX
 | | Crystal structure of Arabidopsis thaliana NAA60 in complex with a bisubstrate analogue | | 分子名称: | Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA | | 著者 | Layer, D, Kopp, J, Lapouge, K, Sinning, I. | | 登録日 | 2019-11-18 | | 公開日 | 2020-06-24 | | 最終更新日 | 2020-12-16 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response.
New Phytol., 228, 2020
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6TH0
 | | Crystal structure of Arabidopsis thaliana NAA60 in complex with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, Acyl-CoA N-acyltransferases (NAT) superfamily protein | | 著者 | Layer, D, Kopp, J, Lapouge, K, Sinning, I. | | 登録日 | 2019-11-18 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response.
New Phytol., 228, 2020
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5MB9
 | | Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Gumiero, A, Weyer, F.A, Valentin Gese, G, Lapouge, K, Sinning, I. | | 登録日 | 2016-11-07 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex.
Nat. Struct. Mol. Biol., 24, 2017
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5NIY
 | | Signal recognition particle-docking protein FtsY | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Signal recognition particle-docking protein FtsY | | 著者 | Kempf, G, Stjepanovic, G, Lapouge, K, Sinning, I. | | 登録日 | 2017-03-27 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane.
Structure, 26, 2018
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6Z00
 | | Arabidopsis thaliana Naa50 in complex with bisubstrate analogue CoA-Ac-MVNAL | | 分子名称: | Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA-LEU | | 著者 | Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I. | | 登録日 | 2020-05-07 | | 公開日 | 2020-12-30 | | 最終更新日 | 2021-05-19 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Structural and functional characterization of the N-terminal acetyltransferase Naa50.
Structure, 29, 2021
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6YZZ
 | | Arabidopsis thaliana Naa50 in complex with AcCoA | | 分子名称: | ACETYL COENZYME *A, N-alpha-acetyltransferase 50 | | 著者 | Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I. | | 登録日 | 2020-05-07 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural and functional characterization of the N-terminal acetyltransferase Naa50.
Structure, 29, 2021
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7OLC
 | | Thermophilic eukaryotic 80S ribosome at idle POST state | | 分子名称: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | 著者 | Kisonaite, M, Wild, K, Sinning, I. | | 登録日 | 2021-05-19 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
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7OLD
 | | Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | | 分子名称: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | 著者 | Kisonaite, M, Wild, K, Sinning, I. | | 登録日 | 2021-05-19 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
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7Z3N
 | | Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-1 conformation | | 分子名称: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | 著者 | Kisonaite, M, Wild, K, Sinning, I. | | 登録日 | 2022-03-02 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
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7Z3O
 | | Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-2 conformation | | 分子名称: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | 著者 | Kisonaite, M, Wild, K, Sinning, I. | | 登録日 | 2022-03-02 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
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5NNP
 | | Structure of Naa15/Naa10 bound to HypK-THB | | 分子名称: | CARBOXYMETHYL COENZYME *A, GLYCEROL, N-terminal acetyltransferase-like protein, ... | | 著者 | Weyer, F.A, Gumiero, A, Kopp, J, Sinning, I. | | 登録日 | 2017-04-10 | | 公開日 | 2017-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | Structural basis of HypK regulating N-terminal acetylation by the NatA complex.
Nat Commun, 8, 2017
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6SXO
 | | Cryo-EM structure of the human Ebp1-ribosome complex | | 分子名称: | 28S ribosomal RNA including ES27L-B (2839-3265), 5.8S ribosomal RNA, 60S ribosomal protein L19, ... | | 著者 | Wild, K, Aleksic, M, Pfeffer, M, Sinning, I. | | 登録日 | 2019-09-26 | | 公開日 | 2020-02-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments.
Nat Commun, 11, 2020
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7BJS
 | | Crystal structure of Khc/atypical Tm1 complex | | 分子名称: | Kinesin heavy chain, SD21996p | | 著者 | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | | 登録日 | 2021-01-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021
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7BJN
 | | Crystal structure of atypical Tm1 (Tm1-I/C), residues 270-334 | | 分子名称: | SD21996p | | 著者 | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | | 登録日 | 2021-01-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021
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7BJG
 | | Crystal structure of atypical Tm1 (Tm1-I/C), residues 262-363 | | 分子名称: | SD21996p | | 著者 | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | | 登録日 | 2021-01-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021
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5M72
 | | Structure of the human SRP68-72 protein-binding domain complex | | 分子名称: | GLYCEROL, POTASSIUM ION, SULFATE ION, ... | | 著者 | Becker, M.M.M, Wild, K, Sinning, I. | | 登録日 | 2016-10-26 | | 公開日 | 2016-12-07 | | 最終更新日 | 2017-01-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
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5M73
 | | Structure of the human SRP S domain with SRP72 RNA-binding domain | | 分子名称: | GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ... | | 著者 | Becker, M.M.M, Wild, K, Sinning, I. | | 登録日 | 2016-10-26 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
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6Y32
 | | Structure of the GTPase heterodimer of human SRP54 and SRalpha | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SULFATE ION, ... | | 著者 | Juaire, K.D, Becker, M.M.M, Wild, K, Sinning, I. | | 登録日 | 2020-02-17 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
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