8PRK
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![BU of 8prk by Molmil](/molmil-images/mine/8prk) | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | Authors: | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | Deposit date: | 1998-09-16 | Release date: | 1998-12-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications. J.Mol.Biol., 284, 1998
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3L31
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![BU of 3l31 by Molmil](/molmil-images/mine/3l31) | Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with the inhibitor, AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Probable manganase-dependent inorganic pyrophosphatase | Authors: | Tuominen, H, Salminen, A, Oksanen, E, Jamsen, J, Heikkila, O, Lehtio, L, Magretova, N.N, Goldman, A, Baykov, A.A, Lahti, R. | Deposit date: | 2009-12-16 | Release date: | 2010-04-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate. J.Mol.Biol., 2010
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117E
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![BU of 117e by Molmil](/molmil-images/mine/117e) | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | Authors: | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | Deposit date: | 1998-09-15 | Release date: | 1998-12-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications. J.Mol.Biol., 284, 1998
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3L2B
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![BU of 3l2b by Molmil](/molmil-images/mine/3l2b) | Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with activator, diadenosine tetraphosphate | Descriptor: | BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Probable manganase-dependent inorganic pyrophosphatase | Authors: | Tuominen, H, Salminen, A, Oksanen, E, Jamsen, J, Heikkila, O, Lehtio, L, Magretova, N.N, Goldman, A, Baykov, A.A, Lahti, R. | Deposit date: | 2009-12-15 | Release date: | 2010-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate. J.Mol.Biol., 2010
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1QEZ
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![BU of 1qez by Molmil](/molmil-images/mine/1qez) | SULFOLOBUS ACIDOCALDARIUS INORGANIC PYROPHOSPHATASE: AN ARCHAEL PYROPHOSPHATASE. | Descriptor: | MAGNESIUM ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | Authors: | Leppanen, V.-M, Nummelin, H, Hansen, T, Lahti, R, Schafer, G, Goldman, A. | Deposit date: | 1999-04-06 | Release date: | 1999-04-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Sulfolobus acidocaldarius inorganic pyrophosphatase: structure, thermostability, and effect of metal ion in an archael pyrophosphatase. Protein Sci., 8, 1999
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1E9G
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![BU of 1e9g by Molmil](/molmil-images/mine/1e9g) | STRUCTURE OF INORGANIC PYROPHOSPHATASE | Descriptor: | INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION | Authors: | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2000-10-12 | Release date: | 2001-03-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase Proc.Natl.Acad.Sci.USA, 98, 2001
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1E6A
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![BU of 1e6a by Molmil](/molmil-images/mine/1e6a) | Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase | Descriptor: | FLUORIDE ION, INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, ... | Authors: | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2000-08-09 | Release date: | 2001-03-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase. Proc. Natl. Acad. Sci. U.S.A., 98, 2001
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1HUJ
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![BU of 1huj by Molmil](/molmil-images/mine/1huj) | |
1I74
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![BU of 1i74 by Molmil](/molmil-images/mine/1i74) | STREPTOCOCCUS MUTANS INORGANIC PYROPHOSPHATASE | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, PROBABLE MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE, ... | Authors: | Merckel, M.C, Fabrichniy, I.P, Goldman, A, Lahti, R, Salminen, A. | Deposit date: | 2001-03-07 | Release date: | 2001-06-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Streptococcus mutans pyrophosphatase: a new fold for an old mechanism. Structure, 9, 2001
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1HUK
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![BU of 1huk by Molmil](/molmil-images/mine/1huk) | |
1WPP
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![BU of 1wpp by Molmil](/molmil-images/mine/1wpp) | Structure of Streptococcus gordonii inorganic pyrophosphatase | Descriptor: | CHLORIDE ION, Probable manganese-dependent inorganic pyrophosphatase, SULFATE ION, ... | Authors: | Fabrichniy, I.P, Lehtio, L, Salminen, A, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2004-09-09 | Release date: | 2004-11-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion Biochemistry, 43, 2004
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1WPN
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![BU of 1wpn by Molmil](/molmil-images/mine/1wpn) | Crystal structure of the N-terminal core of Bacillus subtilis inorganic pyrophosphatase | Descriptor: | MANGANESE (II) ION, Manganese-dependent inorganic pyrophosphatase, SULFATE ION | Authors: | Fabrichniy, I.P, Lehtio, L, Salminen, A, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2004-09-09 | Release date: | 2004-11-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion Biochemistry, 43, 2004
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1WPM
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![BU of 1wpm by Molmil](/molmil-images/mine/1wpm) | Structure of Bacillus subtilis inorganic pyrophosphatase | Descriptor: | Manganese-dependent inorganic pyrophosphatase, SULFATE ION, TETRAETHYLENE GLYCOL | Authors: | Fabrichniy, I.P, Lehtio, L, Salminen, A, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2004-09-09 | Release date: | 2004-11-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion Biochemistry, 43, 2004
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2IHP
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![BU of 2ihp by Molmil](/molmil-images/mine/2ihp) | Yeast inorganic pyrophosphatase with magnesium and phosphate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Inorganic pyrophosphatase, MAGNESIUM ION, ... | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-09-27 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2IK0
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![BU of 2ik0 by Molmil](/molmil-images/mine/2ik0) | Yeast inorganic pyrophosphatase variant E48D with magnesium and phosphate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Inorganic pyrophosphatase, MAGNESIUM ION, ... | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-10-02 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2IK4
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![BU of 2ik4 by Molmil](/molmil-images/mine/2ik4) | Yeast inorganic pyrophosphatase variant D117E with magnesium and phosphate | Descriptor: | Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-10-02 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2IK7
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![BU of 2ik7 by Molmil](/molmil-images/mine/2ik7) | Yeast inorganic pyrophosphatase variant D120N with magnesium and phosphate | Descriptor: | Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-10-02 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2IK2
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![BU of 2ik2 by Molmil](/molmil-images/mine/2ik2) | Yeast inorganic pyrophosphatase variant D115E with magnesium and phosphate | Descriptor: | Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-10-02 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2IK6
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![BU of 2ik6 by Molmil](/molmil-images/mine/2ik6) | Yeast inorganic pyrophosphatase variant D120E with magnesium and phosphate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Inorganic pyrophosphatase, MAGNESIUM ION, ... | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-10-02 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2IK9
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![BU of 2ik9 by Molmil](/molmil-images/mine/2ik9) | Yeast inorganic pyrophosphatase variant D152E with magnesium and phosphate | Descriptor: | Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-10-02 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2IK1
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![BU of 2ik1 by Molmil](/molmil-images/mine/2ik1) | Yeast inorganic pyrophosphatase variant Y93F with magnesium and phosphate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Inorganic pyrophosphatase, MAGNESIUM ION | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | Deposit date: | 2006-10-02 | Release date: | 2007-02-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase. Biochemistry, 46, 2007
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2EIP
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![BU of 2eip by Molmil](/molmil-images/mine/2eip) | INORGANIC PYROPHOSPHATASE | Descriptor: | SOLUBLE INORGANIC PYROPHOSPHATASE | Authors: | Kankare, J.A, Salminen, T, Goldman, A. | Deposit date: | 1996-01-10 | Release date: | 1996-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Escherichia coli inorganic pyrophosphatase at 2.2 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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1IPW
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![BU of 1ipw by Molmil](/molmil-images/mine/1ipw) | |
1FAJ
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![BU of 1faj by Molmil](/molmil-images/mine/1faj) | INORGANIC PYROPHOSPHATASE | Descriptor: | SOLUBLE INORGANIC PYROPHOSPHATASE | Authors: | Kankare, J.A, Salminen, T, Goldman, A. | Deposit date: | 1996-01-10 | Release date: | 1996-11-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of Escherichia coli inorganic pyrophosphatase at 2.2 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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1WGI
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![BU of 1wgi by Molmil](/molmil-images/mine/1wgi) | |