1I74

STREPTOCOCCUS MUTANS INORGANIC PYROPHOSPHATASE

Summary for 1I74

• Entry DOI: 10.2210/pdb1i74/pdb
• Descriptor: PROBABLE MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Streptococcus mutans
• Cellular location: Cytoplasm (By similarity): O68579
• Total number of polymer chains: 2
• Total formula weight: 67724.34

Authors

Merckel, M.C.,Fabrichniy, I.P.,Goldman, A.,Lahti, R.,Salminen, A. (deposition date: 2001-03-07, release date: 2001-06-06, Last modification date: 2024-11-06)

Primary citation

Merckel, M.C.,Fabrichniy, I.P.,Salminen, A.,Kalkkinen, N.,Baykov, A.A.,Lahti, R.,Goldman, A.
Crystal structure of Streptococcus mutans pyrophosphatase: a new fold for an old mechanism.
Structure, 9:289-297, 2001

PubMed Abstract: Streptococcus mutans pyrophosphatase (Sm-PPase) is a member of a relatively uncommon but widely dispersed sequence family (family II) of inorganic pyrophosphatases. A structure will answer two main questions: is it structurally similar to the family I PPases, and is the mechanism similar?

PubMed: 11525166
DOI: 10.1016/S0969-2126(01)00587-1

Experimental method

X-RAY DIFFRACTION (2.2 Å)