1M22
 
 | | X-ray structure of native peptide amidase from Stenotrophomonas maltophilia at 1.4 A | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, peptide amidase | | Authors: | Labahn, J, Neumann, S, Buldt, G, Kula, M.-R, Granzin, J. | | Deposit date: | 2002-06-21 | | Release date: | 2002-10-16 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | An alternative mechanism for amidase signature enzymes
J.MOL.BIOL., 322, 2002
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1M21
 | | Crystal structure analysis of the peptide amidase PAM in complex with the competitive inhibitor chymostatin | | Descriptor: | CHYMOSTATIN, Peptide Amidase | | Authors: | Labahn, J, Neumann, S, Buldt, G, Kula, M.-R, Granzin, J. | | Deposit date: | 2002-06-21 | | Release date: | 2002-10-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | An alternative mechanism for amidase signature enzymes
J.MOL.BIOL., 322, 2002
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1MPG
 | | 3-METHYLADENINE DNA GLYCOSYLASE II FROM ESCHERICHIA COLI | | Descriptor: | 3-METHYLADENINE DNA GLYCOSYLASE II, GLYCEROL | | Authors: | Labahn, J, Schaerer, O.D, Long, A, Ezaz-Nikpay, K, Verdine, G.L, Ellenberger, T.E. | | Deposit date: | 1997-10-28 | | Release date: | 1998-01-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the excision repair of alkylation-damaged DNA.
Cell(Cambridge,Mass.), 86, 1996
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4QCJ
 | | Crystal Structure of OdhI from Corynebacterium glutamicum | | Descriptor: | Oxoglutarate dehydrogenase inhibitor | | Authors: | Labahn, J, Raasch, K, Eggeling, L, Bocola, M, Leitner, A, Bott, M. | | Deposit date: | 2014-05-12 | | Release date: | 2014-07-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model.
J.Biotechnol., 191, 2014
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1FIA
 | | CRYSTAL STRUCTURE OF THE FACTOR FOR INVERSION STIMULATION FIS AT 2.0 ANGSTROMS RESOLUTION | | Descriptor: | FACTOR FOR INVERSION STIMULATION (FIS) | | Authors: | Kostrewa, D, Granzin, J, Choe, H.-W, Labahn, J, Saenger, W. | | Deposit date: | 1991-12-18 | | Release date: | 1993-10-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the factor for inversion stimulation FIS at 2.0 A resolution.
J.Mol.Biol., 226, 1992
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2F93
 | | K Intermediate Structure of Sensory Rhodopsin II/Transducer Complex in Combination with the Ground State Structure | | Descriptor: | RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ... | | Authors: | Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I. | | Deposit date: | 2005-12-05 | | Release date: | 2006-03-07 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
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2F95
 | | M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure | | Descriptor: | RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ... | | Authors: | Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I. | | Deposit date: | 2005-12-05 | | Release date: | 2006-03-07 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
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7PYR
 | | Crystal structure of the adenosine A2A receptor (A2A-PSB1-bRIL) in complex with preladenant conjugate PSB-2115 | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[2-[2-[2-[2-[2-[4-[4-[2-[7-azanyl-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-10-yl]ethyl]piperazin-1-yl]phenoxy]ethanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]-~{N}-[5-[2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-8-yl]pentyl]ethanamide, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, ... | | Authors: | Claff, T, Klapschinski, T.A, Tiruttani Subhramanyam, U.K, Vaassen, V.J, Schlegel, J.G, Vielmuth, C, Voss, J.H, Labahn, J, Muller, C.E. | | Deposit date: | 2021-10-11 | | Release date: | 2022-03-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Single Stabilizing Point Mutation Enables High-Resolution Co-Crystal Structures of the Adenosine A 2A Receptor with Preladenant Conjugates.
Angew.Chem.Int.Ed.Engl., 61, 2022
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7PX4
 | | Crystal structure of the adenosine A2A receptor (A2A-PSB1-bRIL) in complex with preladenant conjugate PSB-2113 | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, CHOLESTEROL, ... | | Authors: | Claff, T, Klapschinski, T.A, Tiruttani Subhramanyam, U.K, Vaassen, V.J, Schlegel, J.G, Vielmuth, C, Voss, J.H, Labahn, J, Muller, C.E. | | Deposit date: | 2021-10-07 | | Release date: | 2022-03-02 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Single Stabilizing Point Mutation Enables High-Resolution Co-Crystal Structures of the Adenosine A 2A Receptor with Preladenant Conjugates.
Angew.Chem.Int.Ed.Engl., 61, 2022
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5FIY
 | | crystal structure of coiled coil domain of PAWR | | Descriptor: | POTASSIUM ION, PRKC APOPTOSIS WT1 REGULATOR PROTEIN | | Authors: | Tiruttani Subhramanyam, U.K, Kubicek, J, Eidhoff, U.B, Labahn, J. | | Deposit date: | 2015-10-03 | | Release date: | 2016-11-16 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the regulatory interactions of proapoptotic Par-4.
Cell Death Differ., 24, 2017
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1H2S
 | | Molecular basis of transmenbrane signalling by sensory rhodopsin II-transducer complex | | Descriptor: | RETINAL, SENSORY RHODOPSIN II, SENSORY RHODOPSIN II TRANSDUCER, ... | | Authors: | Gordeliy, V.I, Labahn, J, Moukhametzianov, R, Efremov, R, Granzin, J, Schlesinger, R, Bueldt, G, Savopol, T, Scheidig, A, Klare, J.P, Engelhard, M. | | Deposit date: | 2002-08-15 | | Release date: | 2002-10-10 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Molecular Basis of Transmembrane Signalling by Sensory Rhodopsin II-Transducer Complex
Nature, 419, 2002
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5OQV
 | | Near-atomic resolution fibril structure of complete amyloid-beta(1-42) by cryo-EM | | Descriptor: | Amyloid beta A4 protein | | Authors: | Gremer, L, Schoelzel, D, Schenk, C, Reinartz, E, Labahn, J, Ravelli, R, Tusche, M, Lopez-Iglesias, C, Hoyer, W, Heise, H, Willbold, D, Schroeder, G.F. | | Deposit date: | 2017-08-14 | | Release date: | 2017-09-13 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Fibril structure of amyloid-beta (1-42) by cryo-electron microscopy.
Science, 358, 2017
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1AYR
 | | ARRESTIN FROM BOVINE ROD OUTER SEGMENTS | | Descriptor: | ARRESTIN | | Authors: | Granzin, J, Wilden, U, Choe, H.-W, Labahn, J, Krafft, B, Bueldt, G. | | Deposit date: | 1997-11-10 | | Release date: | 1998-11-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | X-ray crystal structure of arrestin from bovine rod outer segments.
Nature, 391, 1998
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9HH5
 | | Crystal Structure of nsp15 Endoribonuclease from SARS CoV-2 in Complex with Sepantronium (YM-155) | | Descriptor: | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nsp15 - Uridylate-specific endoribonuclease, ... | | Authors: | Chatziefthymiou, S.D, Kolbe, M, Hakanpaeae, J, Labahn, J, Windshuegel, B. | | Deposit date: | 2024-11-21 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Identification, validation, and characterization of approved and investigational drugs interfering with the SARS-CoV-2 endoribonuclease Nsp15.
Protein Sci., 34, 2025
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9HH6
 | | Crystal Structure of Nsp15 Endoribonuclease from SARS CoV-2 in Complex with TAS-103 | | Descriptor: | 1,2-ETHANEDIOL, 6-[2-(dimethylamino)ethylamino]-3-oxidanyl-indeno[2,1-c]quinolin-7-one, ORF1ab polyprotein, ... | | Authors: | Chatziefthymiou, S.D, Kolbe, M, Hakanpaeae, J, Labahn, J, Windshuegel, B. | | Deposit date: | 2024-11-21 | | Release date: | 2025-05-28 | | Method: | SOLUTION SCATTERING (2 Å), X-RAY DIFFRACTION | | Cite: | Identification, validation, and characterization of approved and investigational drugs interfering with the SARS-CoV-2 endoribonuclease Nsp15.
Protein Sci., 34, 2025
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2ADM
 | | ADENINE-N6-DNA-METHYLTRANSFERASE TAQI | | Descriptor: | ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYLMETHIONINE | | Authors: | Schluckebier, G, Saenger, W. | | Deposit date: | 1996-07-15 | | Release date: | 1997-01-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
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1AQJ
 | | STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI | | Descriptor: | ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, SINEFUNGIN | | Authors: | Schluckebier, G, Saenger, W. | | Deposit date: | 1996-07-25 | | Release date: | 1997-02-12 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
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1AQI
 | | STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI | | Descriptor: | ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Schluckebier, G, Saenger, W. | | Deposit date: | 1996-07-25 | | Release date: | 1997-02-12 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
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