5X5X
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![BU of 5x5x by Molmil](/molmil-images/mine/5x5x) | Crystal structure of the Fab fragment of anti-osteocalcin C-terminal peptide antibody KTM219 | Descriptor: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, Fd chain of anti-osteocalcin antibody KTM219, ... | Authors: | Komatsu, M, Dong, J, Ueda, H, Arai, R. | Deposit date: | 2017-02-18 | Release date: | 2018-02-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the Fab fragment of anti-osteocalcin C-terminal peptide antibody KTM219 To be published
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4ZY3
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![BU of 4zy3 by Molmil](/molmil-images/mine/4zy3) | Crystal Structure of Keap1 in Complex with a small chemical compound, K67 | Descriptor: | FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide) | Authors: | Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M. | Deposit date: | 2015-05-21 | Release date: | 2016-05-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming Nat Commun, 7, 2016
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2RRU
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![BU of 2rru by Molmil](/molmil-images/mine/2rru) | Solution structure of the UBA omain of p62 and its interaction with ubiquitin | Descriptor: | Sequestosome-1 | Authors: | Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H. | Deposit date: | 2011-06-09 | Release date: | 2011-06-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Crystal structure of the UBA omain of p62 and its interaction with ubiquitin To be Published
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1WXS
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![BU of 1wxs by Molmil](/molmil-images/mine/1wxs) | Solution Structure of Ufm1, a ubiquitin-fold modifier | Descriptor: | Ubiquitin-fold Modifier 1 | Authors: | Sasakawa, H, Sakata, E, Yamaguchi, Y, Komatsu, M, Tatsumi, K, Kominami, E, Tanaka, K, Kato, K. | Deposit date: | 2005-02-01 | Release date: | 2006-04-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1 Biochem.Biophys.Res.Commun., 343, 2006
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3WDZ
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![BU of 3wdz by Molmil](/molmil-images/mine/3wdz) | Crystal Structure of Keap1 in Complex with phosphorylated p62 | Descriptor: | Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1 | Authors: | Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M. | Deposit date: | 2013-06-26 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol.Cell, 51, 2013
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3WIM
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![BU of 3wim by Molmil](/molmil-images/mine/3wim) | GABARAP-LIR peptide complex | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, WD repeat and FYVE domain-containing protein 3 | Authors: | Lystad, A, Ichimura, Y, Takagi, K, Yang, Y, Pankiv, S, Mizushima, T, Komatsu, M, Simonsen, A. | Deposit date: | 2013-09-19 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | GABARAP-LIR peptide complex To be Published, 2014
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2D1I
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![BU of 2d1i by Molmil](/molmil-images/mine/2d1i) | Structure of human Atg4b | Descriptor: | Cysteine protease APG4B | Authors: | Kumanomidou, T, Mizushima, T, Komatsu, M, Suzuki, A, Tanida, I, Sou, Y.S, Ueno, T, Kominami, E, Tanaka, K, Yamane, T. | Deposit date: | 2005-08-24 | Release date: | 2006-01-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of Human Atg4b, a Processing and De-conjugating Enzyme for Autophagosome-forming Modifiers J.Mol.Biol., 355, 2006
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3B0F
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![BU of 3b0f by Molmil](/molmil-images/mine/3b0f) | Crystal structure of the UBA domain of p62 and its interaction with ubiquitin | Descriptor: | SULFATE ION, Sequestosome-1 | Authors: | Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H. | Deposit date: | 2011-06-09 | Release date: | 2011-06-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin. J.Biol.Chem., 286, 2011
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2Z6P
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![BU of 2z6p by Molmil](/molmil-images/mine/2z6p) | Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 | Descriptor: | Ufm1-conjugating enzyme 1 | Authors: | Mizushima , T, Tatsumi, K, Ozaki, Y, Kawakami, T, Suzuki, A, Ogasahara, K, Komatsu, M, Kominami, E, Tanaka, K, Yamane, T. | Deposit date: | 2007-08-06 | Release date: | 2007-09-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Ufc1, the Ufm1-conjugating enzyme Biochem.Biophys.Res.Commun., 362, 2007
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2Z6O
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![BU of 2z6o by Molmil](/molmil-images/mine/2z6o) | Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 | Descriptor: | MAGNESIUM ION, Ufm1-conjugating enzyme 1 | Authors: | Mizushima , T, Tatsumi, K, Ozaki, Y, Kawakami, T, Suzuki, A, Ogasahara, K, Komatsu, M, Kominami, E, Tanaka, K, Yamane, T. | Deposit date: | 2007-08-06 | Release date: | 2007-09-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of Ufc1, the Ufm1-conjugating enzyme Biochem.Biophys.Res.Commun., 362, 2007
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2ZJD
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![BU of 2zjd by Molmil](/molmil-images/mine/2zjd) | Crystal Structure of LC3-p62 complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B precursor, undecameric peptide from Sequestosome-1 | Authors: | Ichimura, Y, Kumanomidou, T, Sou, Y, Mizushima, T, Ezaki, J, Ueno, T, Kominami, E, Yamane, T, Tanaka, K, Komatsu, M. | Deposit date: | 2008-03-05 | Release date: | 2008-06-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structural Basis for Sorting Mechanism of p62 in Selective Autophagy J.Biol.Chem., 283, 2008
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3ADE
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![BU of 3ade by Molmil](/molmil-images/mine/3ade) | Crystal Structure of Keap1 in Complex with Sequestosome-1/p62 | Descriptor: | Kelch-like ECH-associated protein 1, SULFATE ION, Sequestosome-1 | Authors: | Kurokawa, H, Yamamoto, M. | Deposit date: | 2010-01-19 | Release date: | 2010-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 Nat.Cell Biol., 12, 2010
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7W3O
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![BU of 7w3o by Molmil](/molmil-images/mine/7w3o) | Crystal structure of human CYB5R3 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3 soluble form | Authors: | Noda, N.N. | Deposit date: | 2021-11-25 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3. Nat Commun, 13, 2022
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7W3N
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![BU of 7w3n by Molmil](/molmil-images/mine/7w3n) | Crystal structure of Ufm1 fused to UFBP1 UFIM | Descriptor: | UFBP1 peptide,Ubiquitin-fold modifier 1 | Authors: | Noda, N.N. | Deposit date: | 2021-11-25 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3. Nat Commun, 13, 2022
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5HKH
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![BU of 5hkh by Molmil](/molmil-images/mine/5hkh) | Crystal structure of Ufm1 in complex with UBA5 | Descriptor: | ASP-ASN-GLU-TRP-GLY-ILE-GLU-LEU-VAL, Ubiquitin-fold modifier 1 | Authors: | Huber, J, Doetsch, V, Rogov, V.V, Akutsu, M. | Deposit date: | 2016-01-14 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation. J.Biol.Chem., 291, 2016
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3OQC
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![BU of 3oqc by Molmil](/molmil-images/mine/3oqc) | |
7YO8
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![BU of 7yo8 by Molmil](/molmil-images/mine/7yo8) | |
7YO9
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![BU of 7yo9 by Molmil](/molmil-images/mine/7yo9) | |
6HB9
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![BU of 6hb9 by Molmil](/molmil-images/mine/6hb9) | |
6H8C
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![BU of 6h8c by Molmil](/molmil-images/mine/6h8c) | Structure of the human GABARAPL2 protein in complex with the UBA5 LIR motif | Descriptor: | Gamma-aminobutyric acid receptor-associated protein-like 2, Ubiquitin-like modifier-activating enzyme 5 | Authors: | Huber, J, Loehr, F, Gruber, J, Akutsu, M, Guentert, P, Doetsch, V, Rogov, V.V. | Deposit date: | 2018-08-02 | Release date: | 2019-05-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy, 16, 2020
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2MGW
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![BU of 2mgw by Molmil](/molmil-images/mine/2mgw) | Solution Structure of the UBA Domain of Human NBR1 | Descriptor: | Next to BRCA1 gene 1 protein | Authors: | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | Deposit date: | 2013-11-09 | Release date: | 2014-04-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin. J.Biol.Chem., 289, 2014
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2MJ5
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![BU of 2mj5 by Molmil](/molmil-images/mine/2mj5) | Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin | Descriptor: | Next to BRCA1 gene 1 protein, Polyubiquitin-C | Authors: | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | Deposit date: | 2013-12-25 | Release date: | 2014-04-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin. J.Biol.Chem., 289, 2014
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2ZJ3
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![BU of 2zj3 by Molmil](/molmil-images/mine/2zj3) | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | Authors: | Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H. | Deposit date: | 2008-02-29 | Release date: | 2009-01-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes Febs Lett., 583, 2009
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2ZJ4
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![BU of 2zj4 by Molmil](/molmil-images/mine/2zj4) | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | Descriptor: | 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | Authors: | Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H. | Deposit date: | 2008-02-29 | Release date: | 2009-01-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes Febs Lett., 583, 2009
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