7VMM
 
 | | Structure of recombinant RyR2 (EGTA dataset, class 1, closed state) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMQ
 | | Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
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7VMR
 | | Structure of recombinant RyR2 mutant K4593A (EGTA dataset) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMO
 | | Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMN
 | | Structure of recombinant RyR2 (EGTA dataset, class 2, closed state) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMP
 | | Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMS
 | | Structure of recombinant RyR2 mutant K4593A (Ca2+ dataset) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
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6KIQ
 | | Complex of yeast cytoplasmic dynein MTBD-High and MT with DTT | | Descriptor: | Alpha tubulin, Dynein heavy chain, cytoplasmic, ... | | Authors: | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | | Deposit date: | 2019-07-19 | | Release date: | 2020-03-04 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.62 Å) | | Cite: | Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
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6KJN
 | | The microtubule-binding domains of yeast cytoplasmic dynein in the high affinity state | | Descriptor: | Dynein heavy chain, cytoplasmic | | Authors: | Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M. | | Deposit date: | 2019-07-22 | | Release date: | 2020-03-18 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
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6KIO
 | | Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT | | Descriptor: | Dynein heavy chain, cytoplasmic, Tubulin alpha-1A chain, ... | | Authors: | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | | Deposit date: | 2019-07-19 | | Release date: | 2020-03-04 | | Last modified: | 2020-03-11 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
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6KJO
 | | The microtubule-binding domains of yeast cytoplasmic dynein in the low affinity state | | Descriptor: | Dynein heavy chain, cytoplasmic | | Authors: | Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M. | | Deposit date: | 2019-07-22 | | Release date: | 2020-03-18 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
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7VKU
 | | Cryo-EM structure of SAM-Tom40 intermediate complex | | Descriptor: | Mitochondrial import receptor subunit TOM40, Sorting assembly machinery 35 kDa subunit, Sorting assembly machinery 37 kDa subunit, ... | | Authors: | Takeda, H, Tsutsumi, A, Kikkawa, M, Endo, T. | | Deposit date: | 2021-10-01 | | Release date: | 2023-01-04 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structure of SAM-Tom40 intermediate complex
To Be Published
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8XEJ
 | | Cryo-EM structure of human XKR8-basigin complex in lipid nanodisc | | Descriptor: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab heavy chain, Fab light chain, ... | | Authors: | Sakuragi, T.S, Kanai, R.K, Kikkawa, M.K, Toyoshima, C.T, Nagata, S.N. | | Deposit date: | 2023-12-12 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase.
J.Biol.Chem., 300, 2024
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5ZSU
 | | Structure of the human homo-hexameric LRRC8A channel at 4.25 Angstroms | | Descriptor: | Volume-regulated anion channel subunit LRRC8A | | Authors: | Kasuya, G, Nakane, T, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | | Deposit date: | 2018-04-29 | | Release date: | 2018-08-15 | | Last modified: | 2018-09-26 | | Method: | ELECTRON MICROSCOPY (4.25 Å) | | Cite: | Cryo-EM structures of the human volume-regulated anion channel LRRC8.
Nat. Struct. Mol. Biol., 25, 2018
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3VSY
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5HLE
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8J80
 | | Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-unbound conformation | | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | Authors: | Han, B.B, Inaba, K, Watanabe, S. | | Deposit date: | 2023-04-28 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
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8J7V
 | | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation | | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | | Authors: | Han, B.B, Inaba, K, Watanabe, S. | | Deposit date: | 2023-04-28 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
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8J7U
 | | Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing conformation | | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | Authors: | Han, B.B, Inaba, K, Watanabe, S. | | Deposit date: | 2023-04-28 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
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8J7W
 | | Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-bound conformation | | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | Authors: | Han, B.B, Inaba, K, Watanabe, S. | | Deposit date: | 2023-04-28 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
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8J7X
 | | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation | | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | | Authors: | Han, B.B, Inaba, K, Watanabe, S. | | Deposit date: | 2023-04-28 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
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8J7Y
 | | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in outward-facing conformation | | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | Authors: | Han, B.B, Inaba, K, Watanabe, S. | | Deposit date: | 2023-04-28 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
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8J7T
 | | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation | | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | | Authors: | Han, B.B, Inaba, K, Watanabe, S. | | Deposit date: | 2023-04-28 | | Release date: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
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6LVY
 | | Crystal structure of TLR7/Cpd-2 (SM-360320) complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-2-(2-methoxyethoxy)-9-(phenylmethyl)-7H-purin-8-one, ... | | Authors: | Zhang, Z, Ohto, U, Shimizu, T. | | Deposit date: | 2020-02-06 | | Release date: | 2020-11-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
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6LW0
 | | Crystal structure of TLR7/Cpd-6 (DSR-139293) complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-ethoxy-8-(5-fluoranylpyridin-3-yl)-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purin-6-amine, ... | | Authors: | Zhang, Z, Ohto, U, Shimizu, T. | | Deposit date: | 2020-02-06 | | Release date: | 2020-11-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
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