2N0Y
 
 | | NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH | | Descriptor: | Non-structural protein NS-S, RNA polymerase II transcription factor B subunit 1 | | Authors: | Cyr, N, de la Fuente, C, Lecoq, L, Guendel, I, Chabot, P.R, Kehn-Hall, K, Omichinski, J.G. | | Deposit date: | 2015-03-18 | | Release date: | 2015-04-22 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | A Omega XaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence.
Proc.Natl.Acad.Sci.USA, 112, 2015
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8T2L
 | | Crystal structure of LC3A in complex with the LIR of NSs4 | | Descriptor: | Non-structural protein S,Microtubule-associated proteins 1A/1B light chain 3A chimera | | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | | Deposit date: | 2023-06-06 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
Plos Pathog., 20, 2024
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8T2N
 | | Crystal structure of GABARAP in complex with the LIR of NSs3 | | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, Non-structural protein S | | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | | Deposit date: | 2023-06-06 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
Plos Pathog., 20, 2024
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8T2M
 | | Crystal structure of GABARAP in complex with the LIR of NSs4 | | Descriptor: | Non-structural protein S,Gamma-aminobutyric acid receptor-associated protein chimera | | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | | Deposit date: | 2023-06-06 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
Plos Pathog., 20, 2024
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8IV3
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8IQJ
 | | Crystal structure of SARS-CoV2 N-NTD | | Descriptor: | Nucleoprotein | | Authors: | Hong, J.Y, Hou, M.H. | | Deposit date: | 2023-03-16 | | Release date: | 2024-02-07 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Targeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2.
Biophys.J., 123, 2024
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8J6X
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6KL5
 | | Structure of The N-terminal domain of Middle East respiratory syndrome coronavirus Nucleocapsid Protein complexed with Benzyl 2-(Hydroxymethyl)-1-Indolinecarboxylate | | Descriptor: | (phenylmethyl) (2S)-2-(hydroxymethyl)-2,3-dihydroindole-1-carboxylate, Nucleoprotein | | Authors: | Hou, M.H, Lin, S.M, Hsu, J.N, Wang, Y.S. | | Deposit date: | 2019-07-29 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.
J.Med.Chem., 63, 2020
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6KL6
 | | Crystal structure of MERS-CoV N-NTD complexed with 5-Benzyloxygramine | | Descriptor: | N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine, Nucleoprotein | | Authors: | Hou, M.H, Lin, S.M, Wang, Y.S, Hsu, J.N. | | Deposit date: | 2019-07-29 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.
J.Med.Chem., 63, 2020
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6KL2
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