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3TIX
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BU of 3tix by Molmil
Crystal structure of the Chp1-Tas3 complex core
Descriptor: CHLORIDE ION, Chromo domain-containing protein 1, POTASSIUM ION, ...
Authors:Schalch, T, Joshua-Tor, L.
Deposit date:2011-08-22
Release date:2011-11-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9001 Å)
Cite:The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS.
Nat.Struct.Mol.Biol., 18, 2011
3V2U
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BU of 3v2u by Molmil
Crystal structure of the yeast GAL regulon complex of the repressor, Gal80p, and the transducer, Gal3p, with galactose and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Galactose/lactose metabolism regulatory protein GAL80, ...
Authors:Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L.
Deposit date:2011-12-12
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.
Genes Dev., 26, 2012
3V5R
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BU of 3v5r by Molmil
Crystal structure of the unliganded form of Gal3p
Descriptor: Protein GAL3, SULFATE ION
Authors:Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L.
Deposit date:2011-12-16
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.
Genes Dev., 26, 2012
3BTV
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BU of 3btv by Molmil
Crystal structure of the super-repressor mutant of Gal80p from Saccharomyces cerevisiae; Gal80(S0)-[G301R]
Descriptor: Galactose/lactose metabolism regulatory protein GAL80
Authors:Kumar, P.R, Joshua-Tor, L.
Deposit date:2007-12-31
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NADP regulates the yeast GAL induction system.
Science, 319, 2008
3BTU
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BU of 3btu by Molmil
Crystal structure of the super-repressor mutant of Gal80p from Saccharomyces cerevisiae; Gal80(S2) [E351K]
Descriptor: Galactose/lactose metabolism regulatory protein GAL80
Authors:Kumar, P.R, Joshua-Tor, L.
Deposit date:2007-12-30
Release date:2008-03-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:NADP regulates the yeast GAL induction system.
Science, 319, 2008
3BTS
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BU of 3bts by Molmil
Crystal structure of a ternary complex of the transcriptional repressor Gal80p (Gal80S0 [G301R]) and the acidic activation domain of Gal4p (aa 854-874) from Saccharomyces cerevisiae with NAD
Descriptor: Galactose/lactose metabolism regulatory protein GAL80, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Regulatory protein GAL4
Authors:Kumar, P.R, Joshua-Tor, L.
Deposit date:2007-12-30
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:NADP regulates the yeast GAL induction system.
Science, 319, 2008
4F3T
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BU of 4f3t by Molmil
Human Argonaute-2 - miR-20a complex
Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*UP*AP*GP*UP*G*CP*AP*GP*G)-3')
Authors:Elkayam, E, Kuhn, C.-D, Tocilj, A, Joshua-Tor, L.
Deposit date:2012-05-09
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Structure of Human Argonaute-2 in Complex with miR-20a.
Cell(Cambridge,Mass.), 150, 2012
4GGJ
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BU of 4ggj by Molmil
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD)
Descriptor: Mitochondrial cardiolipin hydrolase, ZINC ION
Authors:Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L.
Deposit date:2012-08-06
Release date:2012-10-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491, 2012
4GGK
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BU of 4ggk by Molmil
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate
Descriptor: Mitochondrial cardiolipin hydrolase, TUNGSTATE(VI)ION, ZINC ION
Authors:Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L.
Deposit date:2012-08-06
Release date:2012-10-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491, 2012
4KRE
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BU of 4kre by Molmil
Structure of Human Argonaute-1 bound to endogenous Sf9 RNA
Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*A*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
4KRF
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BU of 4krf by Molmil
Structure of Human Argonaute-1 let-7 complex
Descriptor: Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
4O9D
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BU of 4o9d by Molmil
Structure of Dos1 propeller
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Rik1-associated factor 1
Authors:Kuscu, C, Schalch, T, Joshua-Tor, L.
Deposit date:2014-01-02
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PMW
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BU of 4pmw by Molmil
Structure of mouse Dis3L2 in complex with oligoU RNA substrate
Descriptor: DIS3-like exonuclease 2, MAGNESIUM ION, U-U-U-U-U-U-U-U-U-U-U-U-U-U
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2014-05-22
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.
Nature, 514, 2014
4X4P
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BU of 4x4p by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCAC
Descriptor: CCA-adding enzyme, G70A tRNA minihelix ending in CCAC, SULFATE ION
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
4X4S
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BU of 4x4s by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACC and CTP
Descriptor: CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, D(-)-TARTARIC ACID, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme.
Cell, 160, 2015
4X4O
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BU of 4x4o by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix and CTP
Descriptor: CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, G70A tRNA minihelix, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
4X4U
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BU of 4x4u by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a human MenBeta minihelix ending in CCACC
Descriptor: CCA-adding enzyme, DI(HYDROXYETHYL)ETHER, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
1GSV
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BU of 1gsv by Molmil
Crystal structure of the P65 crystal form of photoactive yellow protein G47S mutant
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2002-01-08
Release date:2002-02-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSX
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BU of 1gsx by Molmil
CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S/G51S MUTANT
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
4X4R
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BU of 4x4r by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACC and AMPcPP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CCA-adding enzyme, D(-)-TARTARIC ACID, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.202 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
4X4V
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BU of 4x4v by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a human MenBeta minihelix ending in CCACC and AMPcPP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CCA-adding enzyme, D(-)-TARTARIC ACID, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
1GSW
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BU of 1gsw by Molmil
CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G51S MUTANT
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
4X4W
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BU of 4x4w by Molmil
Crystal structure of the full-length human mitochondrial CCA-adding enzyme
Descriptor: CCA tRNA nucleotidyltransferase 1, mitochondrial, CHLORIDE ION, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
4X4N
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BU of 4x4n by Molmil
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix
Descriptor: CCA-adding enzyme, G70A tRNA minihelix, GLYCEROL, ...
Authors:Kuhn, C.-D, Joshua-Tor, L.
Deposit date:2014-12-03
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.953 Å)
Cite:On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell, 160, 2015
1KQJ
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BU of 1kqj by Molmil
Crystal Structure of a Mutant of MutY Catalytic Domain
Descriptor: A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L.
Deposit date:2002-01-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002

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