3VQH
 
 | | Bromine SAD partially resolves multiple binding modes for PKA inhibitor H-89 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, cAMP-dependent protein kinase catalytic subunit alpha, ... | | Authors: | Pflug, A, Johnson, K.A, Engh, R.A. | | Deposit date: | 2012-03-23 | | Release date: | 2012-08-15 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Anomalous dispersion analysis of inhibitor flexibility: a case study of the kinase inhibitor H-89
Acta Crystallogr.,Sect.F, 68, 2012
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4AO6
 | | Native structure of a novel cold-adapted esterase from an Arctic intertidal metagenomic library | | Descriptor: | ESTERASE | | Authors: | Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B. | | Deposit date: | 2012-03-23 | | Release date: | 2012-08-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library.
Appl.Microbiol.Biotechnol., 97, 2013
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4AO7
 | | Zinc bound structure of a novel cold-adapted esterase from an Arctic intertidal metagenomic library | | Descriptor: | ESTERASE, ZINC ION | | Authors: | Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B. | | Deposit date: | 2012-03-23 | | Release date: | 2012-08-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library.
Appl.Microbiol.Biotechnol., 97, 2013
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4AO8
 | | PEG-bound complex of a novel cold-adapted esterase from an Arctic intertidal metagenomic library | | Descriptor: | DI(HYDROXYETHYL)ETHER, ESTERASE | | Authors: | Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B. | | Deposit date: | 2012-03-23 | | Release date: | 2012-08-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library.
Appl.Microbiol.Biotechnol., 97, 2013
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3FFE
 | | Structure of Achromobactin Synthetase Protein D, (AcsD) | | Descriptor: | AcsD | | Authors: | McMahon, S.A, Liu, H, Carter, L, Oke, M, Johnson, K.A, Schmelz, S, Challis, G.L, White, M.F, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF) | | Deposit date: | 2008-12-03 | | Release date: | 2009-02-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis
Nat.Chem.Biol., 5, 2009
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4TRT
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2X3F
 | | Crystal Structure of the Methicillin-Resistant Staphylococcus aureus Sar2676, a Pantothenate Synthetase. | | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, PANTHOTHENATE SYNTHETASE, SULFATE ION | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | | Deposit date: | 2010-01-24 | | Release date: | 2010-07-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genom., 11, 2010
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2X5F
 | | Crystal structure of the methicillin-resistant Staphylococcus aureus Sar2028, an aspartate_tyrosine_phenylalanine pyridoxal-5'-phosphate dependent aminotransferase | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ASPARTATE_TYROSINE_PHENYLALANINE PYRIDOXAL-5' PHOSPHATE-DEPENDENT AMINOTRANSFERASE, MAGNESIUM ION, ... | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | | Deposit date: | 2010-02-08 | | Release date: | 2010-07-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genom., 11, 2010
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7S4X
 | | Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | | Authors: | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | | Deposit date: | 2021-09-09 | | Release date: | 2022-03-02 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
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7S4U
 | | Cryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-point | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, Target strand, ... | | Authors: | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | | Deposit date: | 2021-09-09 | | Release date: | 2022-03-02 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
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7S4V
 | | Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | | Deposit date: | 2021-09-09 | | Release date: | 2022-03-02 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
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4LYL
 | | Crystal structure of uracil-DNA glycosylase from cod (Gadus morhua) in complex with the proteinaceous inhibitor UGI | | Descriptor: | Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor | | Authors: | Assefa, N.G, Niiranen, L.M.K, Johnson, K.A, Leiros, H.-K.S, Smalas, A.O, Willassen, N.P, Moe, E. | | Deposit date: | 2013-07-31 | | Release date: | 2014-08-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structural and biophysical analysis of interactions between cod and human uracil-DNA N-glycosylase (UNG) and UNG inhibitor (Ugi).
Acta Crystallogr.,Sect.D, 70, 2014
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1GVH
 | | The X-ray structure of ferric Escherichia coli flavohemoglobin reveals an unespected geometry of the distal heme pocket | | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, FLAVOHEMOPROTEIN, ... | | Authors: | Ilari, A, Johnson, K.A, Bonamore, A, Farina, A, Boffi, A. | | Deposit date: | 2002-02-13 | | Release date: | 2002-08-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | The X-Ray Structure of Ferric Escherichia Coli Flavohemoglobin Reveals an Unexpected Geometry of the Distal Heme Pocket
J.Biol.Chem., 277, 2002
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1IL1
 | | Crystal structure of G3-519, an anti-HIV monoclonal antibody | | Descriptor: | monoclonal antibody G3-519 (heavy chain), monoclonal antibody G3-519 (light chain) | | Authors: | Berry, M.B, Johnson, K.A, Radding, W, Fung, M, Liou, R, Phillips Jr, G.N. | | Deposit date: | 2001-05-07 | | Release date: | 2001-05-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of an anti-HIV monoclonal Fab antibody fragment specific to a gp120 C-4 region peptide.
Proteins, 45, 2001
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1OGQ
 | | The crystal structure of PGIP (polygalacturonase inhibiting protein), a leucine rich repeat protein involved in plant defense | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, POLYGALACTURONASE INHIBITING PROTEIN | | Authors: | Di Matteo, A, Federici, L, Mattei, B, Salvi, G, Johnson, K.A, Savino, C, De Lorenzo, G, Tsernoglou, D, Cervone, F. | | Deposit date: | 2003-05-08 | | Release date: | 2003-07-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of Polygalacturonase-Inhibiting Protein (Pgip), a Leucine-Rich Repeat Protein Involved in Plant Defense
Proc.Natl.Acad.Sci.USA, 100, 2003
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2X5G
 | | Crystal structure of the ORF131L51M mutant from Sulfolobus islandicus rudivirus 1 | | Descriptor: | CHLORIDE ION, MALONATE ION, ORF 131 | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Naismith, J.H, White, M.F. | | Deposit date: | 2010-02-08 | | Release date: | 2010-07-21 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genom., 11, 2010
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2X7I
 | | Crystal structure of mevalonate kinase from methicillin-resistant Staphylococcus aureus MRSA252 | | Descriptor: | CHLORIDE ION, CITRIC ACID, MEVALONATE KINASE | | Authors: | Oke, M, Yan, X, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | | Deposit date: | 2010-02-27 | | Release date: | 2010-07-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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2X5T
 | | Crystal structure of ORF131 from Sulfolobus islandicus rudivirus 1 | | Descriptor: | MALONATE ION, ORF 131 | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Naismith, J.H, White, M.F. | | Deposit date: | 2010-02-10 | | Release date: | 2010-07-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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2X7B
 | | Crystal structure of the N-terminal acetylase Ard1 from Sulfolobus solfataricus P2 | | Descriptor: | CHLORIDE ION, COENZYME A, N-ACETYLTRANSFERASE SSO0209 | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Mackay, D, White, M.F, Taylor, G.L, Naismith, J.H. | | Deposit date: | 2010-02-25 | | Release date: | 2010-07-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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2X3D
 | | Crystal Structure of SSo6206 from Sulfolobus solfataricus P2 | | Descriptor: | SSO6206 | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, McMahon, S.A, McEwan, A.R, White, M.F, Naismith, J.H. | | Deposit date: | 2010-01-24 | | Release date: | 2010-07-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Scottish Structural Proteomics Facility: targets, methods and outputs.
J. Struct. Funct. Genomics, 11, 2010
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2X4I
 | | ORF 114a from Sulfolobus islandicus rudivirus 1 | | Descriptor: | UNCHARACTERIZED PROTEIN 114 | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Naismith, J.H, White, M.F. | | Deposit date: | 2010-01-31 | | Release date: | 2010-07-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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2X5H
 | | Crystal structure of the ORF131 L26M L51M double mutant from Sulfolobus islandicus rudivirus 1 | | Descriptor: | ORF 131, SULFATE ION | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Naismith, J.H, White, M.F. | | Deposit date: | 2010-02-08 | | Release date: | 2010-07-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genom., 11, 2010
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2X48
 | | ORF 55 from Sulfolobus islandicus rudivirus 1 | | Descriptor: | CAG38821, PHOSPHATE ION | | Authors: | Oke, M, Carter, L, Johnson, K.A, Liu, H, Mcmahon, S, Naismith, J.H, White, M.F. | | Deposit date: | 2010-01-28 | | Release date: | 2010-07-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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2X3M
 | | Crystal Structure of Hypothetical Protein ORF239 from Pyrobaculum Spherical Virus | | Descriptor: | HYPOTHETICAL PROTEIN ORF239 | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | | Deposit date: | 2010-01-25 | | Release date: | 2011-02-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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2X4G
 | | Crystal structure of PA4631, a nucleoside-diphosphate-sugar epimerase from Pseudomonas aeruginosa | | Descriptor: | NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE | | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | | Deposit date: | 2010-01-30 | | Release date: | 2010-07-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
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